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    Glossary Pregnenolone

    steroid hormone precursor to progesterone, estrogen, testosterone, and cortisol

    Pregnenolone is a steroid hormone that serves as a precursor to various other hormones, including progesterone, estrogen, testosterone, and cortisol. It is synthesized from cholesterol in the adrenal glands, liver, and brain, playing a crucial role in the body's hormonal balance and overall health.

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    Research 30 of 404

    1. Pregnenolone for the treatment of L-DOPA-induced dyskinesia in Parkinson's disease Experimental neurology · 2023 · 2 citations
    2. SERUM STEROIDS AND PITUITARY HORMONES IN FEMALE PUBERTY: A PARTLY LONGITUDINAL STUDY Clinical Endocrinology · 1980 · 186 citations
    3. ς<sub>1</sub>Receptor-Related Neuroactive Steroids Modulate Cocaine-Induced Reward Journal of Neuroscience · 2003 · 100 citations
    4. The significance of CYP11A1 expression in skin physiology and pathology Molecular and Cellular Endocrinology · 2021 · 91 citations
    5. Sigma 1 receptor-related neuroactive steroids modulate cocaine-induced reward. PubMed · 2003 · 91 citations
    6. Relationships between cerebrospinal fluid GABAergic neurosteroid levels and symptom severity in men with PTSD Psychoneuroendocrinology · 2018 · 59 citations
    7. GC-MS determination of steroids related to androgen biosynthesis in human hair with pentafluorophenyldimethylsilyl–trimethylsilyl derivatisation The Analyst · 1999 · 56 citations
    8. Sex steroid synthesis in human skin in situ: The roles of aromatase and steroidogenic acute regulatory protein in the homeostasis of human skin Molecular and Cellular Endocrinology · 2012 · 46 citations
    9. Targeting neurosteroid synthesis as a therapy for schizophrenia-related alterations induced by early psychosocial stress Schizophrenia Research · 2015 · 24 citations
    10. Alteration of neonatal Allopregnanolone levels affects exploration, anxiety, aversive learning and adult behavioural response to intrahippocampal neurosteroids Behavioural Brain Research · 2012 · 24 citations
    11. Isotope Dilution-Based Targeted and Nontargeted Carbonyl Neurosteroid/Steroid Profiling Analytical chemistry · 2018 · 12 citations
    12. Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases Current Medicinal Chemistry · 2016 · 11 citations
    13. Interaction between early postnatal neurosteroid manipulations and adult infusion of neurosteroids into CA1 hippocampal region on the open field behaviour Behavioural Brain Research · 2010 · 11 citations
    14. Hair Steroid Profiling Reveals Racial Differences in Male Pattern Baldness between Korean and Caucasian Populations 2012 · 10 citations
    15. The gut‐microbiota‐brain axis: Focus on gut steroids Journal of Neuroendocrinology · 2024 · 8 citations
    16. Testicular Steroidogenesis Endocrinology · 2017 · 5 citations
    17. Mitochondrial dysfunction in diabetic neuropathy may be involved in the development of neuropathic pain via a reduction in neurosteroid synthesis F1000Research · 2017 · 4 citations
    18. Effect of Topical Hormones Aging Human Skin 1967 · 3 citations
    19. The influence of low dose finasteride, a type II 5α-reductase inhibitor, on circulating neuroactive steroids Hormone Molecular Biology and Clinical Investigation · 2009 · 2 citations
    20. Cutaneous hydroxystereoid dehydrogenases and rat-hair-cycle Archives of Dermatological Research · 1975 · 2 citations
    21. [Neurosteroidogenesis and exploratory responses in rodents]. PubMed · 2014 · 1 citations
    22. New Synthesis of Finasteride Chinese Journal of Pharmaceuticals · 2003 · 1 citations
    23. Mitochondrial dysfunction in an animal model of diabetic neuropathy is associated with a reduction of neurosteroid synthesis. F1000Research · 2018 · 1 citations
    24. Serum and hair steroid profiles and their associations with body composition in adolescence. Open Access CRIS of the University of Bern · 2025
    25. Serum and hair steroid profiles and their associations with body composition in adolescence European Journal of Endocrinology · 2025
    26. Altered Hormone and Bioactive Lipid Plasma Profile in Rodent Models of Polycystic Ovarian Syndrome Revealed by Targeted Mass Spectrometry Journal of Endocrinology and Metabolism · 2025
    27. Altered Hormone and Bioactive Lipid Plasma Profile in Rodent Models of Polycystic Ovarian Syndrome Revealed by Targeted Mass Spectrometry bioRxiv (Cold Spring Harbor Laboratory) · 2024
    28. Study on Changes of 19 Steroids in Plasma From 9 Diagnosed Patients With P450 Oxidoreductase Deficiency Research Square (Research Square) · 2021
    29. SHORT-TERM DIABETES IN THE BRAIN: EFFECTS ON NEUROACTIVE STEROIDS, CHOLESTEROL HOMEOSTASIS, AND MITOCHONDRIAL FUNCTIONALITY Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) · 2017
    30. Unraveling the Complex: Changes in Secondary Science Preservice Teachers' Assessment Expertise ProQuest LLC eBooks · 2012