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Glossary Postmenopausal

stage after 12 months without a menstrual period

Postmenopausal refers to the stage in a woman's life that occurs after she has experienced 12 consecutive months without a menstrual period, marking the end of her reproductive years. This phase typically begins in women between the ages of 45 and 55 and is characterized by a decrease in the production of hormones such as estrogen and progesterone, which can lead to various physiological changes and symptoms, including hot flashes, osteoporosis, and changes in hair and skin.

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research Post-menopausal frontal fibrosing alopecia

49 citations , January 2003 in “Clinical and Experimental Dermatology”

This report from the UK reviews the literature on post-menopausal frontal fibrosing alopecia and highlights its under-recognition and distinctive characteristics compared to lichen planopilaris, but does not provide new results.

research Bioidentical Hormone Replacement Therapy at a Hormone Clinic Causing Significant Virilization in a Post-Menopausal Women

May 2021 in “Journal of the Endocrine Society”

This case report highlights the adverse effects of unmonitored bioidentical hormone replacement therapy, emphasizing the need for patient education about its safety and efficacy compared to FDA-regulated hormones.

Examining the Etiology of Telogen Effluvium in Pre- and Postmenopausal Women: A Chart Review Study

research Examining the etiology telogen effluvium in pre- and postmenopausal women A chart review study

August 2003 in “Journal of Investigative Dermatology Symposium Proceedings”

The document did not provide enough information to summarize the causes of hair loss in pre- and postmenopausal women.

research Post Menopausal Hyperandrogenism: A Case of a Steroid Cell Tumor of the Ovary

May 2021 in “Journal of the Endocrine Society”

This case report describes a 48-year-old woman with a history of PCOS and chemotherapy-induced menopause who was found to have a rare ovarian steroid cell tumor causing postmenopausal hyperandrogenism.

research Postmenopausal frontal fibrosing alopecia. Scarring alopecia in a pattern distribution

332 citations , June 1994 in “Archives of Dermatology”

This study found that progressive frontal hairline recession in postmenopausal women may exhibit features similar to fibrosing alopecia, with histologic similarities to lichen planopilaris but lacking lesions of lichen planus.

research Postmenopausal frontal fibrosing alopecia: A frontal variant of lichen planopilaris

329 citations , January 1997 in “Journal of the American Academy of Dermatology”

This study reports that progressive frontal fibrosing alopecia, a distinct and gradually stabilizing form of lichen planopilaris affecting elderly women and often involving eyebrow hair loss, lacks effective treatments.

research Postmenopausal Frontal Fibrosing Alopecia

325 citations , June 1994 in “Archives of Dermatology”

This study observed that progressive frontal recession in postmenopausal women may exhibit features of fibrosing alopecia, suggesting a distinct reaction pattern from typical lichen planopilaris.

research Frontal fibrosing alopecia in postmenopausal women

179 citations , December 2004 in “Journal of The American Academy of Dermatology”

This study observed that frontal fibrosing alopecia in postmenopausal women involves selective follicular inflammation, and finasteride treatment may slow disease progression, suggesting a potential androgen-related component.

research Finasteride Treatment of Patterned Hair Loss in Normoandrogenic Postmenopausal Women

72 citations , January 2004 in “Dermatology”

This study found that oral finasteride, at a dosage of 2.5 mg/day or more, may improve hair growth and appearance in postmenopausal women with pattern hair loss, without adverse effects.

research How should postmenopausal androgen excess be evaluated?

63 citations , March 2011 in “Clinical Endocrinology”

This review examines the evaluation and management of hirsutism and hyperandrogenism in postmenopausal women and reports no new clinical findings.

research Postmenopausal frontal fibrosing alopecia

57 citations , January 2003 in “Clinical and experimental dermatology”

This study identified postmenopausal frontal fibrosing alopecia as a distinct form of scarring alopecia in postmenopausal women, noting a potential link with a history of bilateral oophorectomy.

research The safety of 52 weeks of oral DHEA therapy for postmenopausal women

46 citations , May 2009 in “Maturitas”

This study found that taking a daily oral dose of 50mg DHEA for one year had no significant impact on blood lipids, insulin sensitivity, or the endometrium in postmenopausal women with low libido.

research Finasteride 5 mg/day treatment of patterned hair loss in normo-androgenetic postmenopausal women

44 citations , January 2013 in “International Journal of Trichology”

This study found that 5 mg/day oral finasteride was effective and safe for improving hair outcomes in normoandrogenic postmenopausal women with androgenetic alopecia over 18 months.

research Expression of Snail1 in the fibrotic dermis of postmenopausal frontal fibrosing alopecia: possible involvement of an epithelial-mesenchymal transition and a review of the Japanese patients

29 citations , February 2010 in “British Journal of Dermatology”

This study explores the expression of Snail1 in the fibrotic dermis of postmenopausal women with frontal fibrosing alopecia, suggesting a possible link to epithelial-mesenchymal transition.

research Clinical Case Seminar: Postmenopausal androgen excess-challenges in diagnostic work-up and management of ovarian thecosis

20 citations , October 2017 in “Clinical Endocrinology”

This article reviews existing knowledge on postmenopausal hyperandrogenism and highlights diagnostic challenges, reporting no new clinical results.

research Postmenopausal virilization after spousal use of topical androgens

20 citations , January 2007 in “Fertility and Sterility”

This case report highlights that a postmenopausal woman experienced virilization due to unintentional transdermal absorption of testosterone from her spouse's topical androgen via shared washcloths, underscoring the importance of considering exogenous androgen exposure in similar diagnoses.

Effect of Red Clover Isoflavones on Skin, Appendages, and Mucosal Status in Postmenopausal Women

research Effect of Red Clover Isoflavones over Skin, Appendages, and Mucosal Status in Postmenopausal Women

19 citations , January 2011 in “Obstetrics and gynecology international”

The researchers reported that red clover extract supplementation in postmenopausal women improved subjective assessments of scalp hair, skin, libido, mood, sleep, and tiredness compared to placebo.

research Postmenopausal hyperandrogenism

15 citations , May 2021 in “Climacteric”

This review discusses the characteristics, diagnostic challenges, and management options for postmenopausal hyperandrogenism but reports no new clinical results; it highlights the importance of distinguishing potential androgen-producing tumors or hyperandrogenic disorders.

Methodology and Challenges to Recruitment to a Randomized, Double-Blind, Placebo-Controlled Trial of Oral DHEA in Postmenopausal Women

research Methodology and Challenges to Recruitment to a Randomized, Double-Blind, Placebo-Controlled Trial of Oral DHEA in Postmenopausal Women

9 citations , November 2008 in “Journal of Womens Health”

This study found that recruiting healthy naturally menopausal women for a DHEA therapy trial was challenged by concerns about hormonal treatments and time constraints, impacting study feasibility.

research Persistent Poor Metabolic Profile in Postmenopausal Women With Ovarian Hyperandrogenism After Testosterone Level Normalization

8 citations , April 2019 in “Journal of the Endocrine Society”

In this study, long-term normalization of testosterone levels in postmenopausal women with hyperandrogenism did not improve body mass index, glucose, or lipid metabolism.

research The ovariectomized mouse simulates the pathophysiology of postmenopausal female pattern hair loss

6 citations , April 2017 in “Journal of Dermatological Science”

This study aimed to evaluate the potential use of ovariectomized mice as a model for postmenopausal female pattern hair loss, but it reports no new results.

research An Occult Leydig Cell Tumour in a Postmenopausal Woman Presenting with Alopecia and Hirsutism: A Case Report

3 citations , January 2021 in “touchREVIEWS in Endocrinology”

This case report describes how a 68-year-old woman's hyperandrogenic symptoms improved and testosterone levels normalized after the surgical removal of an occult Leydig cell tumour.

research Hyperandrogenism in a postmenopausal woman: a rare case of ectopic adrenal cortical gland

3 citations , January 2017 in “Gynecological endocrinology”

This case report describes a 63-year-old woman with hyperandrogenism due to an ectopic adrenal gland adenoma on the ovaries, successfully treated with bilateral salpingo-oophorectomy.

research Preparatory work to support the risk assessment for peri‐ and postmenopausal women taking food supplements containing isolated isoflavones

3 citations , October 2015 in “EFSA supporting publications”

Isoflavones may help with menopause symptoms but could be risky for women with hormone-sensitive cancers.

research Frontotemporal hairline recession in a postmenopausal woman

3 citations , April 2015 in “Dermatology practical & conceptual”

Postmenopausal women can experience hairline recession, affecting their quality of life, and more research is needed for treatments.

research Prevalence of female pattern hair loss in postmenopausal women: a cross-sectional study

2 citations , February 2022 in “Menopause”

This study found that female pattern hair loss was common in postmenopausal women, with body mass index being a significant associated factor.

research Steven Kossards postmenopausal frontal fibrosing alopecia (PFFA)--a therapeutic dilemma.

2 citations , January 2010 in “PubMed”

This case report observed no hair regrowth after treating a woman with postmenopausal frontal fibrosing alopecia using systemic and local corticosteroids, suggesting the need for more innovative therapies.

research Leydig cell hyperplasia as a cause of virilization in a postmenopausal woman: A case report

1 citations , August 2023 in “Case Reports in Women s Health”

This case study in a 62-year-old postmenopausal woman highlights Leydig cell hyperplasia as a likely cause of hyperandrogenism of ovarian origin, where bilateral oophorectomy resolved the condition and confirmed the diagnosis through histopathological examination.

research Postmenopausal hyperandrogenism due to an ovarian sex cord-stromal tumour causing elevated dehydroepiandrosterone sulphate: a case report

1 citations , July 2022 in “BMC Women s Health”

This report describes a rare case of elevated serum DHEAS levels in a postmenopausal woman, linked to an ovarian sex cord-stromal tumor rather than the adrenal glands, challenging common assumptions about androgen sources.

research Postmenopausal Ovarian Hyperthecosis Associated with Rapid Testosterone Excess

1 citations , January 2018 in “Journal of Gynecologic Surgery”

This article reports two cases where ovarian hyperthecosis caused hyperandrogenism in postmenopausal women, confirmed by imaging and resolved after bilateral oophorectomy.