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    Glossary Pluripotent Stem Cells

    cells that can develop into nearly any cell type

    Pluripotent Stem Cells (PSCs) are a type of stem cell that have the ability to develop into almost any cell type in the body, including skin, hair, and organ cells. This makes them incredibly valuable for medical research and regenerative medicine, as they can potentially be used to repair or replace damaged tissues and treat various conditions, including alopecia.

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    Research 30 of 1000+

    1. Hair follicle stem cell marker nestin expression in regenerating hair follicles of patients with alopecia areata European Journal of Dermatology · 2011 · 6 citations
    2. Dermal Microvascular Responses of Human Induced Pluripotent Stem Cell–Derived Skin Organoids to Inflammation and Injury American Journal Of Pathology · 2026
    3. Stem Cells in Regenerative Medicine: A Journey from Adult Stem Cells to Induced Pluripotent Cells International Journal of Molecular Sciences · 2025 · 3 citations
    4. Hair follicle associated pluripotent (HAP) stem cells jump from transplanted whiskers to pelage follicles and stimulate hair growth Scientific Reports · 2022
    5. The advantages of hair follicle pluripotent stem cells over embryonic stem cells and induced pluripotent stem cells for regenerative medicine Journal of Dermatological Science · 2010 · 33 citations
    6. Isolation of a Novel Population of Multipotent Adult Stem Cells from Human Hair Follicles American Journal Of Pathology · 2006 · 344 citations
    7. Pathogenesis and regenerative therapy in vitiligo and alopecia areata: focus on hair follicle Frontiers in Medicine · 2025
    8. Isoproterenol directs hair follicle-associated pluripotent (HAP) stem cells to differentiate <i>in vitro</i> to cardiac muscle cells which can be induced to form beating heart-muscle tissue sheets 2016 · 29 citations
    9. Epidermal Wnt/beta-catenin signalling promotes dermal adipocyte differentiation during hair follicle morphogenesis and regeneration Journal of Dermatological Science · 2012
    10. The potential of nestin-expressing hair follicle stem cells in regenerative medicine Expert Opinion on Biological Therapy · 2007 · 50 citations
    11. Hair-follicle-associated pluripotent (HAP) stem cells Journal of dermatological science · 2016
    12. Hair-follicle associated pluripotent (HAP) stem cells differentiate to beating cardiac tissue sheets Journal of Dermatological Science · 2016
    13. Multipotent nestin-positive, keratin-negative hair-follicle bulge stem cells can form neurons Proceedings of the National Academy of Sciences · 2005 · 419 citations
    14. Watching stem cells at work with a flexible multiphoton tomograph 2012
    15. Calcium regulation of stem cells EMBO reports · 2020 · 25 citations
    16. Applications of Mesenchymal Stem Cells in Skin Regeneration and Rejuvenation International Journal of Molecular Sciences · 2021 · 76 citations
    17. Bioengineered skin organoids: from development to applications Military Medical Research · 2023
    18. Pluripotent Stem Cell Technology: A Promising Remedy for Hypopigmentation Disorders Journal of Stem Cell Research & Therapeutics · 2017 · 1 citations
    19. Human pluripotent stem cell-derived skin organoids enabled pathophysiological model of Mycobacterium tuberculosis infection Nature Communications · 2025
    20. Generation of human-induced pluripotent stem cell-derived adherent 3-dimensional skin hair-follicle organoids Organoid · 2022 · 2 citations
    21. Hair Follicle Development in Mouse Pluripotent Stem Cell-Derived Skin Organoids Cell Reports · 2018 · 169 citations
    22. Isolation and Characterization of a Fetal-Maternal Microchimeric Stem Cell Population in Maternal Hair Follicles Long after Parturition Stem cell reviews · 2019 · 12 citations
    23. Body composition changes and inhibition of fat development in vivo implicates androgen in regulation of stem cell lineage allocation Journal of Cellular Biochemistry · 2011 · 37 citations
    24. Function of KLF4 in Stem Cell Biology InTech eBooks · 2013 · 5 citations
    25. The Developmental & Molecular Requirements for Ensuring that Human Pluripotent Stem Cell-Derived Hair Follicle Bulge Stem Cells Have Acquired Competence for Hair Follicle Generation Following Transplantation Cell transplantation · 2021 · 4 citations
    26. Hair-follicle-associated pluripotent (HAP) stem-cell-sheet implantation accelerates cutaneous wound closure and suppresses scar formation in a mouse model Cell Cycle · 2025 · 1 citations
    27. Development of pluripotent stem cell-derived epidermal organoids that generate effective extracellular vesicles in skin regeneration Biomaterials · 2024 · 25 citations
    28. TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network Advanced Science · 2026
    29. Hair regrowth in alopecia areata patients following Stem Cell Educator therapy BMC medicine · 2015 · 55 citations
    30. Highly Pluripotent Adipose-Derived Stem Cell–Enriched Nanofat: A Novel Translational System in Stem Cell Therapy Cell Transplantation · 2023 · 28 citations