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    Glossary Placebo

    substance with no therapeutic effect used in clinical trials

    A placebo is a substance or treatment with no therapeutic effect, often used in clinical trials as a control to test the efficacy of new medications. It is designed to look like the actual drug being tested but does not contain any active ingredients. The placebo effect occurs when patients experience real changes in their health after taking a placebo, due to their belief in the treatment's effectiveness. This phenomenon is crucial for distinguishing between the actual effects of a drug and the psychological impact of believing one is being treated.

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    1. A randomized clinical trial of 5% topical minoxidil versus 2% topical minoxidil and placebo in the treatment of androgenetic alopecia in men Journal of The American Academy of Dermatology · 2002 · 269 citations
    2. A randomized, placebo-controlled trial of 5% and 2% topical minoxidil solutions in the treatment of female pattern hair loss Journal of The American Academy of Dermatology · 2004 · 219 citations
    3. A placebo-controlled, double-blind crossover study of fluoxetine in trichotillomania American Journal of Psychiatry · 1991 · 180 citations
    4. Placebo-controlled oral pulse prednisolone therapy in alopecia areata Journal of the American Academy of Dermatology · 2005 · 141 citations
    5. Changes in hair weight and hair count in men with androgenetic alopecia, after application of 5% and 2% topical minoxidil, placebo, or no treatment Journal of The American Academy of Dermatology · 1999 · 115 citations
    6. Double-blind, placebo-controlled evaluation of topical minoxidil in extensive alopecia areata Journal of The American Academy of Dermatology · 1987 · 104 citations
    7. A randomized, active- and placebo-controlled study of the efficacy and safety of different doses of dutasteride versus placebo and finasteride in the treatment of male subjects with androgenetic alopecia Journal of The American Academy of Dermatology · 2014 · 97 citations
    8. Comparison of Spironolactone, Flutamide, and Finasteride Efficacy in the Treatment of Hirsutism: A Randomized, Double Blind, Placebo-Controlled Trial1 The Journal of Clinical Endocrinology and Metabolism · 2000 · 94 citations
    9. Efficacy, safety, and tolerability of dutasteride 0.5 mg once daily in male patients with male pattern hair loss: A randomized, double-blind, placebo-controlled, phase III study Journal of The American Academy of Dermatology · 2010 · 92 citations
    10. Effects of finasteride in patients with inflammatory chronic pelvic pain syndrome: a double-blind, placebo-controlled, pilot study Urology · 1999 · 65 citations
    11. Global photographic assessment of men aged 18 to 60 years with male pattern hair loss receiving finasteride 1 mg or placebo Journal of The American Academy of Dermatology · 2012 · 35 citations
    12. <i>Curcuma aeruginosa</i>, a novel botanically derived 5α-reductase inhibitor in the treatment of male-pattern baldness: a multicenter, randomized, double-blind, placebo-controlled study Journal of Dermatological Treatment · 2011 · 34 citations
    13. A spilt head study of efficacy of placebo versus platelet-rich plasma injections in the treatment of androgenic alopecia Journal of Cutaneous and Aesthetic Surgery · 2017 · 33 citations
    14. Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne 2003 · 32 citations
    15. A 6-month, randomized, double-blind, placebo-controlled study evaluating the ability of a marine complex supplement to promote hair growth in men with thinning hair Journal of Cosmetic Dermatology · 2016 · 25 citations
    16. A 3-Month, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Ability of an Extra-Strength Marine Protein Supplement to Promote Hair Growth and Decrease Shedding in Women with Self-Perceived Thinning Hair Dermatology Research and Practice · 2015 · 22 citations
    17. A Single-Centre, Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Investigate the Efficacy and Safety of Minoxidil Topical Foam in Frontotemporal and Vertex Androgenetic Alopecia in Men Skin Pharmacology and Physiology · 2015 · 19 citations
    18. A double-blind, placebo-controlled study of inositol in trichotillomania International clinical psychopharmacology · 2016 · 18 citations
    19. The German Double‐Blind Placebo‐Controlled Evaluation of Topical Minoxidil Solution in the Treatment of Early Male Pattern Baldness International Journal of Dermatology · 1988 · 17 citations
    20. Efficacy and safety of a new 10% topical minoxidil versus 5% topical minoxidil and placebo in the treatment of male androgenetic alopecia: a trichoscopic evaluation Journal of Dermatological Treatment · 2019 · 14 citations
    21. Minoxidil 2% lotion for eyebrow enhancement: A randomized, double-blind, placebo-controlled, spilt-face comparative study The Journal of Dermatology · 2013 · 13 citations
    22. AUSTRALIAN TRIAL OF TOPICAL MINOXIDIL AND PLACEBO IN EARLY MALE PATTERN BALDNESS Australasian Journal of Dermatology · 1990 · 11 citations
    23. A randomized, placebo-controlled trial of 1% topical minoxidil solution in the treatment of androgenetic alopecia in Japanese women. PubMed · 2007 · 10 citations
    24. Efficacy and safety of minoxidil 3% lotion for beard enhancement: A randomized, double‐masked, placebo‐controlled study The Journal of Dermatology · 2016 · 9 citations
    25. Intradermal injections with 0.5% minoxidil for the treatment of female androgenetic alopecia: A randomized, placebo‐controlled trial Dermatologic Therapy · 2020 · 7 citations
    26. The Effects of Lower vs Higher Cell Number of Platelet-Rich Plasma (PRP) on Hair Density and Diameter in Androgenetic Alopecia (AGA): A Randomized, Double-Blinded, Placebo, Parallel-Group Half-Scalp IRB-Approved Study. Aesthetic Surgery Journal · 2021 · 6 citations
    27. Safety and efficacy of ALRV5XR in women with androgenetic alopecia or telogen effluvium: A randomised, double-blinded, placebo-controlled clinical trial EClinicalMedicine · 2021 · 6 citations
    28. Sublingual minoxidil for the treatment of male and female pattern hair loss: a randomized, double‐blind, placebo‐controlled, phase 1B clinical trial Journal of The European Academy of Dermatology and Venereology · 2021 · 5 citations
    29. Sesquiterpene-Enriched Extract of <i>Curcuma aeruginosa</i> Roxb. Retards Axillary Hair Growth: A Randomised, Placebo-Controlled, Double-Blind Study Skin Pharmacology and Physiology · 2018 · 5 citations
    30. Efficacy and safety of Latilactobacillus curvatus LB-P9 on hair health: a randomized, double-blind, placebo-controlled clinical trial Frontiers in Nutrition · 2024 · 5 citations