14 citations
,
January 2018 in “Endocrine” This report describes a three-generation family with Cantú syndrome linked to a novel ABCC9 gene variant, featuring acromegaloid appearance and hypertrichosis without growth hormone abnormalities, and suggests a potential association with pituitary adenomas.
2 citations
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December 2024 in “Clinical Endocrinology” This study suggests that persistent symptoms in patients with controlled functioning adenomas may indicate a coexisting PCOS diagnosis, highlighting the need for precise differentiation and timely management of these conditions.
October 2010 in “Reproductive Biomedicine Online” Women with pituitary adenomas often have reproductive issues, like irregular periods and trouble getting pregnant, but not always breast milk production without pregnancy.
October 2025 in “Journal of the Endocrine Society” This case report illustrates a rare instance of mixed germ cell tumor in the pituitary with hyperandrogenism, emphasizing the importance of thorough examination and hormone evaluation in identifying hormonal dysfunctions.
2 citations
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January 2025 in “Medicine” This study in Saudi female patients with hyperprolactinemia found that pituitary imaging is often indicated due to a high prevalence of pituitary anomalies, with prolactin levels showing moderate accuracy in predicting adenomas and a suggested cutoff level of >38.71 ng/mL for diagnosis.
29 citations
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September 1986 in “Journal of the American Veterinary Medical Association” This case study diagnosed a cat with pituitary-dependent hyperadrenocorticism, confirmed by specific hormonal tests and post-mortem findings of adrenal hyperplasia and a pituitary adenoma.
1 citations
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October 2020 in “International Journal of Zoology and Animal Biology” This case report describes the first known occurrence of spontaneous Cushing's disease due to pituitary neoplasia in a New World primate, revealed in a golden lion tamarin.
November 2022 in “Journal of the Endocrine Society” This case study reports that in an 8-year-old male, a pituitary adenoma causing isolated high LH secretion led to early testosterone-driven puberty without typical testicular enlargement, highlighting the differential roles of LH and FSH in pubertal development.
April 2019 in “Journal of the Endocrine Society” This case study highlights the importance of considering broad causes when evaluating hot flashes in middle-aged men, as it detailed a pituitary macroadenoma causing secondary hypogonadism in a man presenting with such symptoms.
36 citations
,
July 1980 in “Journal of Toxicology and Environmental Health” In this animal study, rats given high doses of ethynylestradiol showed dose-related estrogenic effects, delayed tumor onset in females, and no overall increase in tumor incidence compared to controls.
23 citations
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June 2016 in “Journal of Veterinary Internal Medicine” This case series reports three cats diagnosed with hypersomatotropism due to GH-secreting pituitary adenomas without concurrent diabetes mellitus, highlighting the potential for underdiagnosis in non-diabetic cats.
10 citations
,
December 2015 in “Clinics in Dermatology” This review highlights the eye and skin manifestations of endocrine-related metabolic diseases but provides no new clinical results.
October 2025 in “Journal of the Endocrine Society” This case report describes a 35-year-old woman with a Rathke’s cleft cyst presenting with Cushing disease, highlighting the need to evaluate hormonal hypersecretion in atypical pituitary lesions.
April 2019 in “Journal of the Endocrine Society” This case study reports a rare instance of ectopic ACTH secretion from a primary lung neuroendocrine tumor in a young woman, highlighting successful diagnosis and treatment following symptoms of Cushing syndrome, with normalization of ACTH, glucose, and cortisol levels post-surgery.
14 citations
,
February 2007 in “Irish Veterinary Journal” This study reported the first known case of tertiary hypothyroidism in a dog, diagnosed after a Labrador treated for hyperadrenocorticism presented with related symptoms and an MRI-revealed pituitary mass.
August 2026 in “Genetics and Molecular Research” This study found a significant association between prolactin levels and polycystic ovary syndrome (PCOS), recommending precise investigation of prolactin levels in PCOS patients to identify causes of hyperprolactinemia.
October 2023 in “Journal of the Endocrine Society” This case report describes a challenging diagnosis of Cushing’s syndrome using endocrine tests and imaging, which ultimately identified an adrenal etiology. Successful treatment involved a non-invasive desmopressin stimulation test and right adrenalectomy, leading to improvement in symptoms and health outcomes for the patient.
January 2018 in “Karger Kompass” This study reports a case of a woman with Cushing's disease whose initial complaint was hair loss, a rare presenting symptom, despite multiple dermatological signs like easy bruising and violaceous striae being more indicative of the condition.
4 citations
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November 2021 in “Frontiers in endocrinology” This study systematically compared pediatric and adult Cushing's disease patients, revealing more severe and earlier-onset symptoms in males, and distinct gender-specific clinical manifestations.
October 2020 in “Clinical and Experimental Dermatology” Hair loss improved after removing pituitary tumor.
November 2022 in “Journal of the Endocrine Society” This clinical case report identifies xanthomatous hypophysitis in a male patient, highlighting the mismatch between clinical symptoms and MRI findings, which led to a pituitary biopsy and accurate diagnosis instead of unnecessary surgery.
December 2018 in “Neuroradiology” MRI helps distinguish between pituitary adenomas and craniopharyngiomas, guides treatment for pediatric CNS tumors, and assesses rhinocerebral mucormycosis with a high mortality rate in transplanted patients.
October 2023 in “Journal of the Endocrine Society” This case report describes a unique instance where elevated prolactin levels from a pituitary adenoma were associated with hirsutism due to increased dihydrotestosterone, with treatment leading to normalization.
April 2020 in “Journal of the Endocrine Society” This case report describes a 45-year-old woman with recurrent cyclic Cushing’s disease whose symptoms improved with metyrapone and hydrocortisone treatment.
4 citations
,
September 2024 in “Frontiers in Endocrinology” This study found that serum steroid profiling, particularly 11-deoxycortisol, can effectively differentiate between ACC and ACA, while considering sex differences and functional status for other steroids is important.
October 2012 in “Semina. Ciências Agrárias” This case report details a 7-year-old Shih Tzu with pituitary-dependent hyperadrenocorticism, where initial trilostane treatment did not improve skin conditions, necessitating a dosage increase.
35 citations
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February 1994 in “Fundamental and applied toxicology” High doses of finasteride cause cell growth and tumors in mice.
2 citations
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January 2018 in “PubMed” This case report describes a 45-year-old man with a pituitary macroadenoma whose symptoms and tumor size improved significantly after one month of treatment with cabergoline.
April 2021 in “Sri Lanka Journal of Diabetes Endocrinology and Metabolism” This study reports a case of Cushing disease caused by a rare giant pituitary macroadenoma in a 41-year-old woman, requiring additional treatment after unsuccessful surgery.
10 citations
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February 2007 in “Clinical techniques in small animal practice” This review discusses the etiology and clinical findings of atypical hyperadrenocorticism in dogs due to sex steroid imbalance and explores various treatment options, but reports no new results.