30 citations
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April 2020 in “Stem Cell Research & Therapy” PI3K/Akt pathway is crucial for hair growth and regeneration.
9 citations
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June 2023 in “Cells” Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
36 citations
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January 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.
28 citations
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May 2018 in “Scientific reports” Exercise improves insulin sensitivity and hormone regulation in PCOS rats.
12 citations
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July 2022 in “Journal of Bioscience and Bioengineering” Activating the PI3K/Akt pathway improves hair growth by human dermal papilla cells in hair beads.
14 citations
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July 2020 in “Biomolecules & Therapeutics” Vanillic acid from wheat bran may promote hair growth by activating certain cell pathways and reversing hormone-related hair loss.
February 2023 in “PLOS ONE”
28 citations
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July 2019 in “Life Sciences” Ginsenoside Rb1 from Panax ginseng helps mink hair grow by activating certain cell signals.
February 2022 in “Journal of Biomedical Nanotechnology” Shikonin, a small molecule, speeds up burn wound healing and hair growth by activating the PI3K/Akt pathway.
2 citations
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July 2023 in “International Journal of Molecular Sciences” BFNB could be a promising treatment for hair growth.
11 citations
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March 2020 in “Dermatologic Surgery” A substance called Vascular Endothelial Growth Factor can protect certain hair follicle stem cells from damage caused by androgens, suggesting a new possible treatment for hair loss.
106 citations
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December 2016 in “Cell Stem Cell” PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
October 2023 in “Frontiers in endocrinology” Effective PCOS treatments require targeting specific signaling pathways.
2 citations
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January 2023 in “International Journal of Biological Sciences” A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.
January 2022 in “Social Science Research Network” The Ar/miR-221/IGF-1 pathway is involved in male pattern baldness, with miR-221 potentially being a new target for treatment.
5 citations
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January 2019 in “Biological & Pharmaceutical Bulletin” Norgalanthamine helps hair cells grow by activating certain pathways related to hair growth.
July 2023 in “Molecules” Certain natural products may help stimulate hair growth by affecting stem cell activity in the scalp.
14 citations
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January 2020 in “Frontiers in Endocrinology” OCT4 helps granulosa cell growth in early-stage follicles, and FSH increases OCT4 through specific pathways.
3 citations
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December 2022 in “Nutrients” Limonin from young citrus fruits may help with hair growth by affecting cell growth and hair cycle pathways.
October 2023 in “Clinical, Cosmetic and Investigational Dermatology” Supplemented Erzhi Wan may help regrow hair in male pattern baldness by affecting certain cell signaling pathways.
4 citations
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April 2012 in “Medical Hypotheses” Finasteride may improve stem cell therapy for heart attacks by increasing cell survival.
17 citations
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June 2020 in “Animals” lncRNAs may regulate hair follicle development in Hu sheep.
141 citations
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August 2018 in “Nature Reviews Microbiology” Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.
22 citations
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February 2017 in “Clinical and Experimental Dermatology” Icariin helps mouse hair grow by boosting a growth factor in skin cells.
21 citations
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March 2019 in “Critical Reviews in Clinical Laboratory Sciences” The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.
6 citations
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April 2022 in “Frontiers in cell and developmental biology” The research identified key proteins and genes that may influence wool bending in goats.
3 citations
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September 2017 in “Stem cell investigation” PDGF signaling is crucial for maintaining fat stem cells in the skin, and its level of activation can either preserve these cells or cause fibrosis.
1 citations
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March 2024 in “Signal transduction and targeted therapy” NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
January 2024 in “Advanced Science” New microspheres help heal skin wounds and regrow hair without scarring.
January 2024 in “European Journal of Medicinal Chemistry” Natural products might be safe, effective, and affordable treatments for hair loss.