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Dihydrotestosterone gel before hypospadias surgery led to less scarring but raised concerns about potential psychological effects and skin changes.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Genetic mutations can affect female sexual development, requiring personalized medical care.

A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.

Hormone treatment before hypospadias surgery can increase penis size and reduce surgery complications.

Untreated congenital adrenal hyperplasia can lead to complications like stroke and needs glucocorticoid treatment.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Pre-operative hormone treatment for hypospadias surgery might improve outcomes, but more research is needed to confirm.

Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.

Men with urinary symptoms are more likely to have erectile dysfunction, and there's a debate about research methods and authorship ethics.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

Using buccal mucosa for hypospadias repair in children is effective and reduces complications.

Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.

Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.

Most women with hirsutism or androgenic alopecia had polycystic ovaries, especially if they had irregular periods.

Testosterone's muscle-building effects do not require its conversion to DHT.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.