May 2021 in “Journal of the Endocrine Society” This study found that the severity of female pattern hair loss in premenopausal women was associated with clinical signs of hyperandrogenism, such as hirsutism and acne, but not with biochemical parameters.
32 citations
,
January 1990 in “Clinical Endocrinology” This study found that women with female pattern androgenic alopecia have significantly higher levels of certain androgens and androgen sulfates compared to normal premenopausal women, suggesting markers for diagnosis and treatment efficacy.
27 citations
,
January 2015 in “International Journal of Trichology” This study found that a marine-extract dietary supplement significantly reduced hair shedding and increased hair diameter in premenopausal women with subclinical hair thinning or hair loss after 6 months of use.
23 citations
,
November 2018 in “Journal of the European Academy of Dermatology and Venereology” This study observed that frontal fibrosing alopecia is increasingly diagnosed in Italian Caucasian females, often showing premenopausal onset and eyebrow alopecia as an early sign.
18 citations
,
May 2014 in “Menopause” This study found that a 5-mg daily dose of transdermal testosterone cream in postmenopausal women restored testosterone levels to those typical of premenopausal women.
5 citations
,
July 2016 in “Canadian Urological Association journal” This study suggests that age, androgenetic alopecia, metabolic syndrome, and free testosterone levels may significantly affect sexual function in premenopausal women.
1 citations
,
December 2021 in “Siriraj Medical Journal” This study found that low serum ferritin levels were significantly associated with female pattern hair loss in premenopausal women, and maternal family history of androgenetic alopecia influenced its development.
February 2024 in “The journal of sexual medicine” This study suggests that flibanserin may have a similar safety profile in men to that observed in premenopausal women, with positive responses reported for various sexual dysfunctions, but further research is needed.
418 citations
,
June 2003 in “Endocrine Reviews” This review discusses the relationship between polycystic ovary syndrome and cardiovascular risk, noting a possible adverse impact on risk profiles and subclinical atherosclerosis but no clear increase in premenopausal cardiovascular events; it presents no new clinical results.
1 citations
,
January 2019 in “Clinical, Cosmetic and Investigational Dermatology” In this study, a gel containing extracts from Coffea arabica and Larrea divaricata was found to significantly thicken eyebrows and eyelashes in most premenopausal and postmenopausal women, without causing adverse effects, but showed no statistical difference from a placebo in overall hair growth.
123 citations
,
August 2005 in “Journal of the European Academy of Dermatology and Venereology” In this study, the researchers observed that treatment with intralesional and topical corticosteroids, finasteride, and minoxidil may stop the progression of frontal fibrosing alopecia in postmenopausal and premenopausal women.
6 citations
,
June 1983 in “Cancer” This study found that a chemotherapy regimen combining CMFVP and ACP treatments for unresectable metastatic breast cancer yielded a 66.7% overall response rate, with premenopausal women responding more favorably than postmenopausal women.
4 citations
,
June 2018 in “PLOS ONE” This study found that ferritin levels were positively associated with insulin resistance in non-diabetic Korean men and postmenopausal women, but not in premenopausal women.
4 citations
,
June 2017 in “Annales de dermatologie et de vénéréologie” This prospective study in Morocco reported on 20 cases of frontal fibrosing alopecia, finding that dermoscopy played a key role in diagnosing and managing the condition, which can increasingly affect premenopausal women.
3 citations
,
October 2022 in “International Journal of Impotence Research” This article reviews the role of testosterone in sexual health, supporting Testosterone Replacement Therapy as an effective treatment for Hypoactive Sexual Desire Disorder in postmenopausal women, though more research is needed on its long-term effects and applicability to premenopausal women.
May 2023 in “The Journal of Sexual Medicine” In this study, researchers reported significant improvement in sexual function and related symptoms for four patients using off-label flibanserin, suggesting potential broader applications beyond premenopausal women with hypoactive sexual desire disorder.
August 2020 in “Acta medica Iranica” In this study, researchers found that facial papules may be early indicators of frontal fibrosing alopecia and lichen planopilaris, highlighting the importance of early recognition for diagnosis, especially in premenopausal women.
February 2022 in “Pakistan Journal of Medical and Health Sciences” This study reported that finasteride administered at 2.5 mg/day was clinically effective in 62% of women with female pattern hair loss, with greater efficacy observed in those who were premenopausal or had a lower Ludwig score.
This paper reviews female androgenetic alopecia and highlights the importance of differentiating it from other hair loss conditions, noting its potential association with hyperandrogenism in premenopausal women, but reports no new results.
December 2018 in “International journal of women’s dermatology” This case report highlights that frontal fibrosing alopecia may be underrecognized in young women and notes that no single treatment regimen has been proven consistently effective for this condition.
119 citations
,
November 2009 in “Human Reproduction” This study found that women with polycystic ovary syndrome have a higher prevalence of non-alcoholic fatty liver disease and increased androgen bioavailability may be involved alongside metabolic factors.
83 citations
,
April 1992 in “Clinical Endocrinology” This study found that treatment with cyproterone acetate and ethinyl oestradiol increased hair density in women with diffuse androgen-dependent alopecia, particularly when serum ferritin levels were above 40 μg/l.
17 citations
,
June 2016 in “Australasian Journal of Dermatology” In this case report, a 46-year-old woman with familial frontal fibrosis alopecia experienced initial stabilization of hair loss with dutasteride and minoxidil, but artificial hair transplantation led to implant folliculitis, requiring removal of the fibers.
7 citations
,
June 1994 in “Journal of The American Academy of Dermatology” This report describes a possible case of burn-induced bullous pemphigoid, as the disease was transient and did not recur, suggesting a potential link between burns and the condition.
4 citations
,
April 2013 in “Actas Dermo-Sifiliográficas” This study found that hairline measurements in white Spanish women differ from those previously reported for American women, which may be important for hair transplantation evaluations in alopecia cases.
28 citations
,
February 2011 in “Clinical Endocrinology” In this study, women with polycystic ovary syndrome showed adverse lipoprotein profile changes that increase cardiovascular risk, which were found to be more closely related to androgen levels than body weight.
10 citations
,
January 2013 in “Actas Dermo-Sifiliográficas” Most white Spanish women have a widow's peak, and their hairline measurements could help in hair restoration surgery.
2 citations
,
April 2022 in “African Health Sciences” In this study, FLI was significantly higher in women with PCOS and NAFLD compared to those without NAFLD, and an FLI < 30 could not effectively rule out NAFLD in lean PCOS patients.
November 2023 in “International journal of reproduction, contraception, obstetrics and gynecology” This review discusses the hypotheses surrounding the developmental origins of polycystic ovary syndrome, particularly the role of prenatal androgen exposure, and reports no new experimental results.
June 2023 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Bicalutamide mesotherapy improved hair density in women with hair loss and was well received.