October 2023 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This review found that hyperandrogenism in premenopausal women is linked to a higher prevalence of cardiovascular risk factors and diseases regardless of obesity, while in postmenopausal women, these risks depend on obesity.
2 citations
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September 2019 in “Acta Cardiologica” This study found that premenopausal women with non-classic congenital adrenal hyperplasia may have increased cardiometabolic risk compared to healthy women.
This study found that premenopausal exercising women with oligomenorrhea had lower triiodothyronine levels and truncal fat percentage compared to other groups, suggesting distinct energetic and reproductive profiles.
March 2023 in “Pakistan Journal of Medical and Health Sciences” This study found that premenopausal women with female-pattern hair loss had significantly lower serum vitamin D levels compared to healthy controls, suggesting a potential role of vitamin D deficiency in this condition.
January 2026 in “Clinics in Dermatology” This discussion examines the aesthetic symptoms of perimenopause, such as hot flashes and skin changes, and reviews management options like hormone replacement therapy and topical cosmetics, emphasizing the importance of consistency in treatment to maintain results.
108 citations
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March 2006 in “Archives of Dermatology” This study observed that 62% of premenopausal women with female pattern hair loss reported improvement when treated with oral finasteride and an oral contraceptive containing drospirenone and ethinyl estradiol.
13 citations
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August 1980 in “Cancer” This study found that administering chemotherapy to premenopausal women with Stage II breast cancer significantly improved disease-free intervals and increased survival, while postmenopausal women receiving sufficient doses also saw prolonged disease-free periods.
July 2023 in “Endocrinology, diabetes & metabolism case reports” This case report involved a premenopausal woman with rapidly progressing virilizing symptoms caused by a rare sertoliform endometrioid carcinoma of the ovary. Following surgical intervention, her symptoms improved, highlighting the importance of recognizing virilizing symptoms as potential indicators of low-grade ovarian malignancies in similar cases.
May 2019 in “The Journal of Sexual Medicine” This study found that among premenopausal women taking flibanserin, consuming wine with an evening meal may increase the risk of syncope and orthostatic hypotension-related adverse events compared to placebo.
April 2006 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study found that 62% of premenopausal women with female pattern hair loss showed some improvement after 12 months of treatment with finasteride and an oral contraceptive, with no adverse reactions reported.
165 citations
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February 1994 in “Fertility and Sterility” This study found that flutamide was more effective than spironolactone in reducing symptoms of hirsutism and related conditions in premenopausal women, with fewer discontinuations due to side effects.
96 citations
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October 1987 in “The Journal of Clinical Endocrinology & Metabolism” This study found that long-term GnRH agonist administration in premenopausal women with polycystic ovarian disease resulted in persistent suppression of ovarian steroid secretion, while adrenal steroid levels remained unchanged.
93 citations
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June 2001 in “The Journal of Clinical Endocrinology and Metabolism” This study found that serum androgen levels in premenopausal women may be influenced by genetic variants of the androgen receptor and estrogen receptor β genes.
74 citations
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July 2010 in “The Journal of Clinical Endocrinology & Metabolism” This study found that gonadal dysfunction is very common in premenopausal women with acromegaly and may be caused by hyperprolactinemia, GH/IGF-I excess, or tumor effects.
47 citations
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November 2010 in “Vox Sanguinis” This study found that a targeted iron supplementation program prevented anemia and improved blood return rates among premenopausal female blood donors with iron deficiency.
40 citations
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January 2013 in “Journal of Korean Medical Science” This study found that serum ferritin levels were lower in premenopausal women with female pattern hair loss compared to healthy controls, suggesting a potential role for iron in hair loss.
1 citations
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July 2021 in “Frontiers in Oncology” This study found that patient-reported outcomes were similar between neoadjuvant endocrine therapy and chemotherapy in premenopausal breast cancer patients, but future perspective was significantly better with endocrine therapy.
1 citations
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November 2020 in “Cureus” This study found that severity of female pattern hair loss in premenopausal women was related to other clinical signs of hyperandrogenism like hirsutism and acne, but not to biochemical measures of hyperandrogenism.
This review clarifies that non-anaemic iron deficiency in non-pregnant premenopausal women often arises from menstrual iron losses and can cause symptoms like hair loss, while in post-menopausal women and adult men, iron deficiency anaemia frequently indicates chronic intestinal bleeding.
April 2020 in “Online journal of complementary & alternative medicine” This article discusses the FDA approval of bremelanotide for premenopausal women with hypoactive sexual desire disorder and reports no clinical results.
September 2006 in “Fertility and Sterility” This study found a positive association between higher birth weight and self-reported graying of hair in premenopausal infertile women.
January 2023 in “International Journal of Trichology” This study found that bicalutamide mesotherapy resulted in subtle hair density improvements and was well tolerated by premenopausal women with androgenetic alopecia.
108 citations
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January 2003 in “Fertility and Sterility” This study found that flutamide at 250 mg daily modestly improved hair thinning in premenopausal women with hyperandrogenic alopecia over one year, while cyproterone acetate and finasteride were not effective.
33 citations
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January 2015 in “Journal of Cosmetic Dermatology” This study reports that familial frontal fibrosing alopecia was diagnosed earlier in premenopausal women compared to postmenopausal women, though long-term outcomes remain uncertain without a definitive treatment.
May 2024 in “International Society of Hair Restoration Surgery” This abstract highlights that female androgenetic alopecia affects a significant portion of both premenopausal and postmenopausal women, causing considerable psychological distress, yet there are limited treatment options available. Results are not reported.
January 2016 in “International Journal of Research in Medical Sciences” This study found a strong association between chronic telogen effluvium and low levels of hemoglobin, serum ferritin, and thyroid hormones in premenopausal Indian women, with stress also playing a significant role.
This study found that polycystic ovary syndrome was the most common cause of hirsutism among premenopausal Algerian women.
This study found that polycystic ovary syndrome is the most common cause of hirsutism in premenopausal Algerian women, with recommendations for thorough endocrinologic evaluations.
February 2011 in “Journal of the American Academy of Dermatology” This study found that polycystic ovary syndrome was the most common cause of hirsutism among premenopausal women in Algeria.
This study found that polycystic ovary syndrome was the most common cause of hirsutism among premenopausal Algerian women, affecting nearly 60% of participants.