In this study, facial hypertrichosis occurred in 10% of women treated with isotretinoin for acne, but it resolved spontaneously after the treatment ended.
May 2019 in “The Journal of Sexual Medicine” This study found no baseline factors that predicted flibanserin efficacy for HSDD, though low testosterone or use of hormonal contraceptives were associated with reduced efficacy.
36 citations
,
January 2014 in “The Journal of Sexual Medicine” This study found that transdermal testosterone significantly increased the frequency of satisfactory sexual events in women experiencing SSRI/SNRI-related loss of libido, but did not improve overall sexual self-rating scores.
26 citations
,
June 2018 in “Australasian Journal of Dermatology” Stopping sunscreen use on the forehead led to hair regrowth in a woman with frontal fibrosing alopecia.
80 citations
,
January 1988 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study observed that high-dose spironolactone frequently caused metrorrhagia in women with idiopathic hirsutism, leading the authors to suggest lower starting doses or additional hormonal therapy.
39 citations
,
September 2012 in “Human Reproduction” This study found that specific SHBG gene variants, rs727428 and rs6259, were associated with PCOS in Mediterranean women, although the associations were relatively weak and do not indicate a causative role.
1 citations
,
May 2013 in “Journal of the Egyptian Women's Dermatologic Society (Print)” This study found that increased PSA levels in women with hyperandrogenism may serve as a diagnostic marker, comparable to free testosterone levels.
October 1986 in “Inpharma” Spironolactone helps reduce hair growth in women with hirsutism but may cause menstrual irregularities.
1231 citations
,
May 2001 in “Hypertension” This review discusses the potential mechanisms by which androgens may elevate blood pressure, particularly through impacts on the renin-angiotensin system, but reports no new experimental results.
658 citations
,
June 2003 in “Endocrine reviews” This review discusses the role of androgens in the progression of cardiovascular disease and explores novel therapeutic targets without reporting new clinical results.
52 citations
,
November 2009 in “International journal of gynaecology and obstetrics” This study found that hyperandrogenemia in Chinese women with PCOS is associated with higher risks of type 2 diabetes and obesity, suggesting it should be prioritized in managing PCOS-related infertility.
3 citations
,
May 1990 in “Journal of Steroid Biochemistry” This study found that diagnosing non-classical 3 beta-hydroxysteroid dehydrogenase deficiency solely based on elevated serum or urinary 5-ene-steroids may not be reliable.
September 2021 in “Journal of the Egyptian Women's Dermatologic Society (Print)” This study found no significant difference in serum ferritin, zinc, and 25-hydroxy vitamin D levels between women with chronic telogen effluvium and healthy controls, although suboptimal levels were common in both groups.
24 citations
,
September 2015 in “JAAD case reports” This case report describes a patient with frontal fibrosing alopecia experiencing significant hair regrowth and reversal of cutaneous atrophy after treatment with the 5α-reductase inhibitor finasteride.
3 citations
,
January 2012 in “Hanyang Medical Reviews” This review discusses the pathogenesis of hirsutism and related diagnostic criteria for polycystic ovary syndrome in Korean women, but reports no new clinical results.
2 citations
,
June 2009 in “The Nurse practitioner” This article highlights that many women with PCOS are unaware of their condition and its increased risks for type 2 diabetes and cardiovascular disease, and it offers no new clinical findings.
May 2021 in “Journal of the Endocrine Society” This case report describes a 47-year-old woman diagnosed with a rare Sertoliform endometrioid carcinoma of the ovary, emphasizing its early-stage presentation and generally favorable prognosis.
339 citations
,
February 2014 in “Journal of The American Academy of Dermatology” This study found that eyelash loss, facial papules, and body hair involvement were linked to severe frontal fibrosing alopecia, and antiandrogens were the most effective treatment.
255 citations
,
October 1985 in “The Journal of Clinical Endocrinology & Metabolism” This study concluded that albumin-bound testosterone is biologically important and significantly contributes to testosterone bioavailability in women receiving spironolactone.
207 citations
,
April 2006 in “Journal of The American Academy of Dermatology” This review discusses the complexities of diagnosing and treating iron deficiency related to nutritional anemia and hair loss, concluding that routine screening and supplementation for hair loss are not yet supported by sufficient evidence.
75 citations
,
June 1999 in “Pediatric Clinics of North America” This review discusses the clinical features and therapeutic goals for teenagers with PCOS, emphasizing the need for further research into its causes and potential long-term health risks, but reports no new clinical results.
61 citations
,
June 2016 in “Clinical Medicine” This review discusses the relationship between obesity, insulin resistance, and polycystic ovary syndrome and highlights the potential benefits of weight loss for managing PCOS symptoms, but reports no new clinical results.
31 citations
,
April 2010 in “British journal of dermatology/British journal of dermatology, Supplement” This report describes two patients with frontal fibrosing alopecia who developed acute hair loss on their limbs, revealing that the limb alopecia had similar histological features to scalp alopecia.
23 citations
,
April 2021 in “Journal of Clinical Medicine” This review compiles existing data on frontal fibrosing alopecia and highlights the promise of 5-alpha reductase inhibitors as a treatment option, while noting the need for clarity on its cause and progression.
17 citations
,
October 2017 in “Journal of Cutaneous Medicine and Surgery” This review discusses the various treatment options for frontal fibrosing alopecia but reports no definitive results, as no treatment has proven effective in halting hairline recession or promoting hair growth.
15 citations
,
January 1988 in “Drugs” The document concludes that treatments for female hair loss and excessive hair growth are temporary and not well-studied.
13 citations
,
December 2020 in “BMJ Open Diabetes Research & Care” This study found that while intensive lifestyle interventions were associated with favorable changes in SHBG levels due to reduced adiposity, these changes did not consistently predict diabetes risk reduction.
10 citations
,
April 2018 in “Actas Dermo-Sifiliográficas” This study describes the prescribing habits of Spanish dermatologists, highlighting that topical minoxidil and oral finasteride are the most common treatments for male AGA and postmenopausal female AGA.
9 citations
,
January 2020 in “Postepy Dermatologii I Alergologii” This review discusses the enigmatic nature of frontal fibrosing alopecia and reports no clinical results; the authors stress the need for further research.
7 citations
,
October 2012 in “S. Karger AG eBooks” This review discusses the similarities in clinical, endocrine, and ultrasonographic features between PCOS and other disorders with excessive androgen secretion, emphasizing the importance of accurate diagnosis but reports no new clinical results.