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    Glossary Perifollicular

    area surrounding hair follicle

    Perifollicular refers to the area surrounding a hair follicle. In medical and dermatological contexts, this term is often used to describe conditions or observations, such as inflammation or fibrosis, that occur around the hair follicles. For example, perifollicular inflammation is a common feature in certain types of hair loss, like alopecia areata, where the immune system attacks the hair follicles.

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    Research 30 of 1000+

    1. Extracellular Vesicles for Androgenetic Alopecia: Current Evidence, Mechanisms, and Clinical Prospects International Journal of Nanomedicine · 2026
    2. Exosome-Based Therapies: Protocol Development for Androgenetic Alopecia Journal of Craniofacial Surgery Open · 2025
    3. The Central Role of Fibroblasts in Androgenic Alopecia: a systematic umbrella review and meta-meta-analysis Open MIND · 2026
    4. Next Generation Therapeutics for Androgenetic Alopecia OSF Preprints (OSF Preprints) · 2026
    5. LB965 Follicular trochanters: A potential mechanism for stem cell depletion in scarring alopecia 2020
    6. Future Directions in the Treatment of Vitiligo 2018 · 3 citations
    7. Perifollicular haemorrhage with corkscrew hair due to scurvy Postgraduate Medical Journal · 2015 · 9 citations
    8. Perifollicular Melanocyte Regeneration in Bullous Pemphigoid Cureus · 2024
    9. Mitochondrial Dysfunction in Lichen Planopilaris with Focus on Oxidative Stress and Metabolic Reprogramming International journal of research studies in biosciences · 2025
    10. Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration <i>in vivo</i> The EMBO Journal · 2019 · 44 citations
    11. Cell Enriched Autologous Fat Grafts to Follicular Niche Improves Hair Regrowth in Early Androgenetic Alopecia Aesthetic Surgery Journal · 2020 · 8 citations
    12. Stress Inhibits Hair Growth in Mice by Induction of Premature Catagen Development and Deleterious Perifollicular Inflammatory Events via Neuropeptide Substance P-Dependent Pathways American Journal of Pathology · 2003 · 194 citations
    13. From a stem-cell–centered to a niche-centered view: the core role of collagen networks in hair loss and hair follicle miniaturization Frontiers in Cell and Developmental Biology · 2026
    14. The Modulatable Stem Cell Niche: Tissue Interactions during Hair and Feather Follicle Regeneration Journal of Molecular Biology · 2015 · 66 citations
    15. Aging in hair follicle stem cells and niche microenvironment The Journal of Dermatology · 2017 · 38 citations
    16. THBS4 promotes hair regeneration by inducing dermal mechanical niche adaptation Research Square · 2026
    17. Regulation of melanocyte stem cell behavior by the niche microenvironment Pigment Cell & Melanoma Research · 2018 · 24 citations
    18. Human epithelial stem cell survival within their niche requires “tonic” cannabinoid receptor 1‐signalling—Lessons from the hair follicle Experimental Dermatology · 2021 · 14 citations
    19. Macrophages Contribute to the Cyclic Activation of Adult Hair Follicle Stem Cells PLoS Biology · 2014 · 175 citations
    20. Preferential crosstalk between perifollicular capillary vessels and dermal papilla cells during hair cycling homeostasis Scientific Reports · 2026
    21. Terminalia bellirica (Gaertn.) Roxb. extracts reshape the perifollicular microenvironment and regulate the MAPK pathway for androgenetic alopecia treatment Journal of Ethnopharmacology · 2024
    22. Aging‐associated perifollicular changes and calcium deposition in poodles Veterinary Dermatology · 2018 · 2 citations
    23. Proposed mechanisms of low-level light therapy in the treatment of androgenetic alopecia Lasers in Medical Science · 2020 · 8 citations
    24. Clinicopathological characteristics and treatment outcomes of fibrosing alopecia in a pattern distribution: A retrospective cohort study Journal of the European Academy of Dermatology and Venereology · 2021 · 7 citations
    25. Lichen planopilaris in men: a retrospective clinicopathologic study of 19 patients International Journal of Dermatology · 2020 · 2 citations
    26. Clinical and Histopathological Findings in Patients with Follicular Dermatoses: All Skin Diseases Starts in the Hair Follicles as New Hypothesis American Journal of Clinical Research and Reviews · 2020 · 2 citations
    27. Finasteride in Frontal Fibrosing Alopecia: Joining the Dots! Skin appendage disorders · 2020 · 1 citations
    28. Angiopoietin-1 induces survival and proliferation of hair follicle dermal papilla cells through integrin α5β1 signaling Frontiers in Medicine · 2025
    29. In vivo Study of the Effect of 5 and 10% Nebivolol Cream on Hair Growth in Mice Models International journal of drug delivery technology · 2022
    30. Indications for a brain‐hair follicle axis: inhibition of keratinocyte proliferation and up‐regulation of keratinocyte apoptosis in telogen hair follicles by stress and substance P The FASEB Journal · 2001 · 125 citations