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Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Some drugs may reduce prostatitis symptoms short-term with few side effects.

Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.

Finasteride can reduce fertility in some men, but stopping it increases sperm count.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.

Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

Hormone therapy and surgeries for transgender individuals affect their skin and hair, requiring specific dermatologic treatments and respectful care.

Oral contraceptives can cause skin issues like dark patches, acne, yeast infections, sensitivity to light, spider veins, skin rashes, and hair loss.

Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.