December 2024 in “Frontiers in Genetics” This review discusses the genetic causes and pathogenesis of Olmsted syndrome, emphasizing the potential for a genotype-phenotype correlation due to TRPV3 mutations, and explores avenues for individualized treatment developments for this condition.
April 2024 in “International journal of molecular sciences” This study examines the similarities and differences in the pathogenesis of autoimmune conditions alopecia areata and vitiligo, highlighting shared features like immune cell involvement and cytokine pathways, while noting differing immune responses in skin and hair.
June 2023 in “Zenodo (CERN European Organization for Nuclear Research)” In this abstract, the issue of "microinflammation" in hair follicles, central to androgenetic alopecia, is described as involving an inflammatory process with Langerhans cells and keratinocytes presenting antigens to T lymphocytes, leading to an immune response with macrophages or natural killer cells destroying these antigens.
February 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This article reviews the optimization of diagnosing and treating androgen alopecia and analyzes the development processes in this area within the country, but reports no new clinical results.
January 2023 in “Sibirskij medicinskij vestnik” This analysis explores possible causes of menstrual irregularities in women with PCOS following COVID-19, but reports no new clinical findings.
This review compiles existing information on the pathogenesis of androgenetic alopecia, highlighting its genetic, hormonal, and environmental factors, but reports no new clinical findings.
April 2022 in “Jurnal Ilmiah Kesehatan Media Husada” This article reviews various factors contributing to telogen effluvium and examines potential treatments like Minoxidil, but reports no new clinical findings.
November 2020 in “Journal of Bioengineering and Technology Apllied for Health” This review discusses the mechanisms, symptoms, and body system damage caused by SARS-CoV-2, emphasizing the complexity of treatment and suggesting more research is needed to fully understand COVID-19.
June 2019 in “Pediatric Dermatology” This review discusses the pathogenesis and clinical presentations of alopecia in epidermolysis bullosa patients, noting diverse hair abnormalities and emphasizing the lack of a consensus on its natural history.
January 2006 in “Practical Journal of Clinical Medicine” This review discusses the immune-mediated mechanism behind alopecia areata, highlighting similarities between the condition in humans and animals, and reports no new clinical results.
July 1990 in “British Journal of Dermatology”
March 2019 in “Chinese Journal of Dermatology” This review discusses the factors involved in androgenetic alopecia, emphasizing genetic susceptibility as a key contributor and detailing how follicle miniaturization completes the condition's development; it reports no new clinical results.
150 citations
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October 2010 in “The American Journal of Pathology” This review discusses the pathogenesis and challenges in treating primary cicatricial alopecia, highlighting the need to understand immune protection collapse in hair follicle stem cells; it reports no new clinical results.
135 citations
,
April 2017 in “Advances in Clinical and Experimental Medicine” This review discusses the causes, clinical implications, and treatment options for polycystic ovary syndrome and reports no new results; the authors highlight both approved and emerging therapies.
89 citations
,
October 1996 in “Dermatologic Clinics” This review discusses androgenetic alopecia and alopecia areata through a systems biology lens, emphasizing the role of multi-omics data integration to explore molecular mechanisms and potential therapeutic strategies, but offers no new clinical results.
56 citations
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January 2022 in “Burns & Trauma” This study suggests that intercellular communication via the WNT5A and STAT pathways may partly drive EMT-like phenomena in keloid pathogenesis, based on findings in an animal model.
28 citations
,
January 2000 in “Medical Mycology” This article reviews the impact of natural fungal pathogens on laboratory animal research and reports no new results, calling attention to infection risks with dermatophytes, Candida, and pneumonia in immunocompromised rodents.
23 citations
,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” This review discusses rodent models of alopecia areata and suggests they are crucial for understanding the autoimmune mechanisms and potential treatments but reports no new clinical results.
22 citations
,
September 2008 in “International Journal of Dermatology” This case report describes a 41-year-old woman with segmental vitiligo and lichen sclerosus in the perineal region, where treatment with clobetasol ointment improved repigmentation and resolved many symptoms, although some scaling persisted.
20 citations
,
March 2021 in “Cancers” This study found that rare germline pathogenic variants in BRCA2, BRCA1, and ATM are associated with increased risk of aggressive prostate cancer.
17 citations
,
October 2020 in “South African Medical Journal” This review highlights that fungal co-infections, notably with Aspergillus and Candida, are common in hospitalized COVID-19 patients, but their impact on disease outcomes remains unclear, indicating a need for further research.
7 citations
,
November 2024 in “Journal of the American Academy of Dermatology” Genetics, hormones, and microbiome changes contribute to hidradenitis suppurativa.
5 citations
,
July 2020 in “JAMA Dermatology” Minoxidil solution applied twice daily improved hair growth in patients with Woolly Hair/Hypotrichosis due to LIPH gene issues, with mild side effects.
3 citations
,
January 2010 in “Actas Dermo-Sifiliográficas” This study found that a history of immunization and throat carriage of bacterial pathogens, including Streptococcus pyogenes, were associated with increased risk of developing alopecia areata.
1 citations
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January 1989 in “Journal of dermatological treatment” Azelaic acid may help treat acne by killing bacteria, reducing inflammation, and preventing clogged pores.
In this study, researchers found that alopecia areata is linked to immune cell activation against hair follicle autoantigens and is associated with heart changes and cardiac marker alterations in humans and mice.
November 2025 in “SHILAP Revista de lepidopterología” This review systematically evaluates 13 animal and 2 mathematical models for alopecia areata, assessing their effectiveness in understanding the condition's pathogenesis and aiding in the development of new therapeutic strategies.
July 2025 in “Journal of Investigative Dermatology” Schwann cell and M2 macrophage interactions contribute to keloid growth by increasing matrix deposition.
July 2025 in “Journal of Investigative Dermatology” Scarring alopecia involves increased immune cells and specific gene changes near damaged hair follicles.