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    Did you mean Olfactory Receptor?
    Glossary Olfactory Receptor

    specialized protein in the nose that detects odors

    An olfactory receptor (OR) is a specialized protein found in the sensory neurons of the nose that detects odor molecules. When an odor molecule binds to an olfactory receptor, it triggers a signal that is sent to the brain, allowing us to perceive and identify different smells. These receptors are part of a large family of G-protein-coupled receptors and are crucial for the sense of smell.

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    Research 30 of 400

    1. LB1029 The common fragrance, linalool, promotes core hair follicle pathology events associated with frontal fibrosing alopecia through activating a cognate olfactory receptor in the bulge Journal of Investigative Dermatology · 2024
    2. Functional characterization of OR51B5 and OR1G1 in human lung epithelial cells as potential drug targets for non-type 2 lung diseases Cell Biology and Toxicology · 2024 · 4 citations
    3. Targeting olfactory receptor OR2AT4: An innovative aptamer-based treatment for hair growth promotion Molecular Therapy — Nucleic Acids · 2025
    4. Ectopic olfactory receptors in human: New therapeutic possibilities Authorea (Authorea) · 2020
    5. Nonanal Stimulates Growth Factors via Cyclic Adenosine Monophosphate (cAMP) Signaling in Human Hair Follicle Dermal Papilla Cells International Journal of Molecular Sciences · 2020 · 8 citations
    6. Pangenome and genome variation analyses of pigs unveil genomic facets for their adaptation and agronomic characteristics iMeta · 2024
    7. Olfactory receptor OR2AT4 regulates human hair growth Nature Communications · 2018 · 82 citations
    8. Topical odorant application of the specific olfactory receptor OR2AT4 agonist, Sandalore<sup>®</sup>, improves telogen effluvium‐associated parameters Journal of Cosmetic Dermatology · 2020 · 11 citations
    9. OR2AT4, an Ectopic Olfactory Receptor, Suppresses Oxidative Stress-Induced Senescence in Human Keratinocytes Antioxidants · 2022 · 6 citations
    10. 503 A new chemosensory control of human hair growth: Olfactory receptor OR10J1 stimulation promotes scalp hair follicle growth and progenitor cell generation ex vivo Journal of Investigative Dermatology · 2024
    11. 1377 Exploring the factors to regulate sweating by transcriptome analysis for anhidrosis: Novel role of olfactory receptors on sweating via exposing to β-ionone Journal of Investigative Dermatology · 2023
    12. 572 Olfactory Receptor 2A4/7 Activation by the Fragrance, Cyclohexyl Salicylate, Promotes Human Hair Follicle Growth and Stem Cell Progeny Expansion Journal of Investigative Dermatology · 2022
    13. 732 Treatment with cyclohexyl salicylate, an olfactory receptor 2A4/7 agonist, promotes human hair follicle growth and bulge stem cell progeny expansion Journal of Investigative Dermatology · 2022
    14. Beta-caryophyllene enhances wound healing through multiple routes PloS one · 2019 · 67 citations
    15. Pathobiology questions raised by telogen effluvium and trichodynia in COVID‐19 patients Experimental Dermatology · 2021 · 18 citations
    16. New multi-targeting strategy in hair growth promotion: in vitro and in vivo studies Italian journal of dermatology and venereology · 2018 · 3 citations
    17. 495 OR2AT4 activation by a synthetic odorant, stimulates dermcidin production in human hair follicle epithelium and increases follicular resistance to bacterial contamination: A novel antimicrobial folliculitis therapy? 2019
    18. 216 Human hair follicles can “smell”: OR2AT4-mediated hair growth regulation Journal of Investigative Dermatology · 2016
    19. 219 STAT5 activation in the dermal papilla is important for hair follicle growth phase induction, hair follicle regeneration and wound healing Journal of Investigative Dermatology · 2016 · 1 citations
    20. Analysis of androgen receptor expression and activity in the mouse brain Scientific Reports · 2024
    21. 181 Topical Sandalore®, a specific OR2AT4-stimulating odorant, ameliorates telogen effluvium: Randomized, double-blinded, placebo-controlled trial Journal of Investigative Dermatology · 2019
    22. 609 Topical Sandalore®, a specific OR2AT4-stimulating odorant, ameliorates female telogen effluvium: Randomized, double-blinded, placebo-controlled clinical trial Journal of Investigative Dermatology · 2019
    23. AROMA THERAPY: AN ART OF HEALING Indian Research Journal of Pharmacy and Science · 2018 · 15 citations
    24. Realising the therapeutic potential of neuroactive steroid modulators of the GABAA receptor Neurobiology of Stress · 2019 · 40 citations
    25. Touch Receptors Undergo Rapid Remodeling in Healthy Skin Cell Reports · 2016 · 31 citations
    26. Polymeric micelle mediated follicular delivery of spironolactone: Targeting the mineralocorticoid receptor to prevent glucocorticoid-induced activation and delayed cutaneous wound healing International Journal of Pharmaceutics · 2021 · 9 citations
    27. IL-17a induces age-related olfactory dysfunction by impairing regeneration and promoting respiratory metaplasia in mice Nature Communications · 2025
    28. Androgen binding profiles of two distinct nuclear androgen receptors in Atlantic croaker (Micropogonias undulatus) The Journal of Steroid Biochemistry and Molecular Biology · 2000 · 58 citations
    29. Alteration of Ethanol Drinking in Mice via Modulation of the GABAA Receptor with Ganaxolone, Finasteride, and Gaboxadol Alcoholism: Clinical and Experimental Research · 2011 · 34 citations
    30. 1049 Novel strategy to promote hair follicle growth and stem cell activation in human male scalp skin: Targeting prolactin receptor with ABS-201 Journal of Investigative Dermatology · 2026