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β-catenin is essential for stem cell activation and proliferation in hair follicles.

Frontal fibrosing alopecia is a hair loss condition in postmenopausal women, similar to lichen planopilaris, with ineffective treatments.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Laser hair removal is the most requested cosmetic procedure and has become a scientifically-based treatment suitable for all skin types.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Lactate production is important for activating hair growth stem cells.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Hair loss in men is common, treatable, but not curable.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Demodicosis is common and often missed, needing more recognition and treatment in skin care.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Androgens, like testosterone, are crucial for early testicular descent in rats.

Understanding hair follicle anatomy helps diagnose hair disorders.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

Liposomes and niosomes improve finasteride delivery for hair loss treatment.