Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study introduced rPanglaoDB, an R package that facilitates the integration of public scRNA-seq datasets to effectively characterize rare cell types, exemplified by generating the first unbiased transcriptome profile of fibrocytes.

Antisense oligonucleotides show promise for treating Myotonic Dystrophy type I.

This study developed the Alopecia Areata Patient Priority Outcome (AAPPO), a new tool designed to measure and capture the symptoms and impacts of alopecia areata that matter most to patients.

Mini pulse corticosteroid therapy with oral dexamethasone is effective and has fewer side effects for treating extensive alopecia areata.

This study found that the Alopecia Areata Patient Priority Outcomes questionnaire is a reliable and valid tool for measuring the severity and impact of hair loss in individuals with alopecia areata.

This study reported that using piroctone olamine in either a shampoo or leave-on product form significantly increased hair retention and improved scalp condition in women with perceived hair thinning.

This study reported that a newly developed bioadhesive and injectable hydrogel dressing, incorporating hyaluronate-gelatin and the antibiotic doxycycline, accelerated burn wound healing and skin regeneration in rats, highlighting its potential for clinical applications in burn injury therapy.

This historical review traces the discovery of 5-alpha reductase inhibitors, widely used in urology, from the study of guevedoces, Dominican children with a rare disorder leading to significant androgenization at puberty.

This study identified a novel homozygous EDNRA variant linked to Oro-Oto-Cardiac Syndrome and showed that EDNRA signaling is essential for normal craniofacial and cardiovascular development.

This study found that among women with PCOS, the FokI CC genotype of the VDR gene may offer protection against acne and seborrhea, while the VDR-TaqI dominant genotype is associated with reduced oxidative stress.

This review discusses advances in drug delivery systems to enhance oleanolic acid's bioavailability and therapeutic potential but reports no new clinical results.

This study found that PRX102, a peroxidase with a unique polar localization pattern, plays a role in root hair growth by aiding the transport of materials to the tips of growing root hairs.

The study found that different criteria led to different patient groups in the CombAT study compared to the MTOPS study.

This study found that Tinea Corporis significantly impacts the quality of life of patients, with disease duration and body surface area involved being key factors.

This study in a transgenic mouse model found that repressing overexpression of ornithine decarboxylase reduced papilloma development, indicating its role in tumor promotion sensitivity.

This study suggests that dysfunctions and altered expression of aquaporins may play a role in PCOS-related disorders, potentially impacting folliculogenesis and integrating with the insulin-dependent hypothesis of PCOS pathogenesis.

In this study, otitis externa in toy poodles and miniature dachshunds was successfully treated using a video otoscope alongside systemic antibiotics and antifungals, with all dogs recovering fully.

This study found that overexpression of a mutated ornithine decarboxylase transgene in mice led to complete hair loss, which could be prevented or reversed with an ODC inhibitor.

This study found that patients taking hydroxychloroquine had a significantly higher likelihood of indeterminate QuantiFERON-TB Gold test results compared to those not on the medication, independent of other immunosuppressive drug use.

This study reports encouraging results in treating androgenetic alopecia by combining injectable PRF and PDO thread insertion on the scalp.

In this study, the authors developed a novel PROTAC named dAR-6–1, which demonstrated superior hair regeneration in an AGA mouse model compared to minoxidil, highlighting its promise as a therapy due to potent AR degradation and excellent skin permeability.

In this study, Doublebase gel was more effective in maintaining and increasing skin hydration compared to Aqueous cream BP, with higher patient satisfaction and preference for future use.

This study found that in women with PCOS, a combination of finasteride and spironolactone significantly improved all health-related quality of life scales and reduced hyperandrogenism within four months, supporting its role alongside lifestyle measures.

This case report highlights a novel NR5A1 gene variant associated with a severe 46,XY disorder of sex development, stressing the importance of genetic screening in similar cases.

In this study, engineered mice with a mutation similar to that in Olmsted syndrome showed progressive hair loss due to impaired inner root sheath keratinocyte differentiation and stem cell exhaustion.

This study quantified relationships among various occupations in Japan, enabling comparisons with vocational aptitude test results using new numerical criteria developed from analysis of over three million survey panels.