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    Did you mean Non-Classical Adrenal Hyperplasia?
    Glossary Non-Classical Adrenal Hyperplasia

    partial enzyme deficiency causing excess androgen production

    Non-Classical Adrenal Hyperplasia (NCAH) is a milder form of congenital adrenal hyperplasia that typically presents later in life, often during adolescence or adulthood. It is caused by a partial deficiency in the enzyme 21-hydroxylase, leading to an overproduction of androgens (male hormones). Symptoms can include irregular menstrual cycles, excessive hair growth (hirsutism), and acne in females, while males may experience early signs of puberty.

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    1. Phenotypic profiling of parents with cryptic nonclassic congenital adrenal hyperplasia: findings in 145 unrelated families European journal of endocrinology · 2011 · 62 citations
    2. Recommendations for treatment of nonclassic congenital adrenal hyperplasia (NCCAH): An update Steroids · 2011 · 56 citations
    3. Nonclassic Congenital Adrenal Hyperplasia International Journal of Pediatric Endocrinology · 2010 · 49 citations
    4. Nonclassic congenital adrenal hyperplasia Current Opinion in Endocrinology, Diabetes and Obesity · 2012 · 30 citations
    5. The diagnosis of nonclassic congenital adrenal hyperplasia due to 21-hydroxylase deficiency, based on serum basal or post-ACTH stimulation 17-hydroxyprogesterone, can lead to false-positive diagnosis Clinical Endocrinology · 2015 · 25 citations
    6. Nonclassic congenital adrenal hyperplasia and the heterozygote carrier Expert Review of Endocrinology & Metabolism · 2013 · 2 citations
    7. Nonclassic Congenital Adrenal Hyperplasia: An Overview Journal of Pediatric Nursing · 2009
    8. NonClassic Congenital Adrenal Hyperplasia International Journal of Pediatric Endocrinology · 2010 · 59 citations
    9. Sexual Function and Depressive Symptoms in Young Women With Nonclassic Congenital Adrenal Hyperplasia The Journal of Sexual Medicine · 2016 · 11 citations
    10. The Effect of Simvastatin on Plasma Steroid Hormone Levels in Metformin-Treated Women with Non-Classic Congenital Adrenal Hyperplasia Experimental and Clinical Endocrinology & Diabetes · 2016 · 7 citations
    11. Roux-en-Y gastric bypass in the treatment of non-classic congenital adrenal hyperplasia due to 11-hydroxylase deficiency BMJ case reports · 2013 · 5 citations
    12. Challenges in treatment of patients with non-classic congenital adrenal hyperplasia Frontiers in Endocrinology · 2022 · 4 citations
    13. Unusual presentation with polymenorrhagia and markedly high 17-hydroxy progesterone levels in a lady with Non-Classic Congenital Adrenal Hyperplasia. PubMed · 2015 · 1 citations
    14. Severe Hirsutism in Non Classic Congenital Adrenal Hyperplasia: A Case Report and Literature Review Open Access Macedonian Journal of Medical Sciences · 2020
    15. Non-classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency revisited: an update with a special focus on adolescent and adult women Human Reproduction Update · 2017 · 117 citations
    16. Non-classic congenital adrenal hyperplasia Steroids · 2013 · 42 citations
    17. Novel Systematics of Nomenclature and Classification of Female Functional Androgenization (Including Polycystic Ovary Syndrome and Non-Classic Congenital Adrenal Hyperplasia) Journal für Kardiologie (Krause & Pachernegg GmbH) · 2010 · 8 citations
    18. Cardiometabolic risk factors in women with non-classic congenital adrenal hyperplasia Acta Cardiologica · 2019 · 2 citations
    19. Nonclassic adrenal hyperplasia Reviews in endocrine and metabolic disorders · 2008 · 55 citations
    20. Screening for 21-hydroxylase–deficient nonclassic adrenal hyperplasia among hyperandrogenic women: a prospective study Fertility and Sterility · 1999 · 216 citations
    21. Hyperandrogenism in polycystic ovary syndrome and adrenal hyperplasia: finding differences to make a specific diagnosis Archives of Gynecology and Obstetrics · 2025 · 7 citations
    22. Genetic screening of non-classic CAH females with hyperandrogenemia identifies a novel CYP11B1 gene mutation Hormones · 2016
    23. 8368 Functional Evaluation Of Novel CYP21A2 Variants: Expanding The Genetic Basis Of Non-classic CAH Journal of the Endocrine Society · 2024
    24. 9209 Functional Evaluation Of Novel CYP21A2 Variants: Expanding The Genetic Basis Of Non-classic CAH Journal of the Endocrine Society · 2024
    25. Influence of Genotype and Hyperandrogenism on Sexual Function in Women With Congenital Adrenal Hyperplasia The Journal of Sexual Medicine · 2019 · 11 citations
    26. Nonclassic 21-hydroxylase deficiency Fertility and Sterility · 2006 · 13 citations
    27. Approaching fertility in congenital adrenal hyperplasia: exploring P30L mutation-induced 21-hydroxylase deficiency with a presentation between non-classical and simple virilizing phenotypes. A case report Medicine and Pharmacy Reports · 2023
    28. MANAGEMENT OF ENDOCRINE DISEASE Hyperandrogenic states in women: pitfalls in laboratory diagnosis European Journal of Endocrinology · 2018 · 16 citations
    29. Hyperandrogenism in Adolescent Girls KARGER eBooks · 2004 · 10 citations
    30. Approach to the Patient: Hirsutism The Journal of Clinical Endocrinology & Metabolism · 2025