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    Glossary NLRP3

    protein involved in immune response and inflammation regulation

    NLRP3 is a protein that plays a crucial role in the body's immune response. It is part of a larger complex called the inflammasome, which helps detect harmful substances and triggers inflammation to fight off infections. In some cases, overactivation of NLRP3 can lead to chronic inflammatory diseases.

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    Research 30 of 496

    1. Hair follicle mesenchymal stem cell exosomal lncRNA H19 inhibited NLRP3 pyroptosis to promote diabetic mouse skin wound healing Aging · 2023 · 13 citations
    2. Total glucosides of paeony inhibit NLRP3/caspase-1/GSDMD-mediated inflammation and pyroptosis in C3H/HeJ mice with alopecia areata Biomolecules and Biomedicine · 2024 · 5 citations
    3. Melatonin Alleviates the Oxygen–Glucose Deprivation/Reperfusion-Induced Pyroptosis of HEI-OC1 Cells and Cochlear Hair Cells via MT-1,2/Nrf2 (NFE2L2)/ROS/NLRP3 Pathway Molecular Neurobiology · 2022 · 5 citations
    4. 647 NLRP1 promotes tumor growth by enhancing inflammasome activation and suppressing caspase-3 activity in human melanoma Journal of Investigative Dermatology · 2016 · 1 citations
    5. Serum Interleukin 18 and NLRP3 in patients with Alopecia Areata Benha Medical Journal · 2024
    6. 1,25-(OH)2D3 promotes hair growth by inhibiting NLRP3/IL-1β and HIF-1α/IL-1β signaling pathways The Journal of Nutritional Biochemistry · 2024
    7. 1117 PX-12 inhibits NLRP3 inflammasome activation to treat psoriasis Journal of Investigative Dermatology · 2023
    8. Spatiotemporal regulation of acute wound healing by the NLRP3 inflammasome: dual roles in macrophage-fibroblast chemotaxis and phenotype during wound repair Burns & Trauma · 2026
    9. Protective role of agomelatine via modulation of TLR4/NF-κB: NLRP3/IL-1β signaling pathways in testosterone-induced benign prostatic hyperplasia in rats Naunyn-Schmiedeberg s Archives of Pharmacology · 2025
    10. Mechanism of action of NLRP3 protein macromolecule based on electrochemical sensors in the treatment of alopecia areata in mice: The role of Ritlecitinib in AA mice through NLRP3 Microchemical Journal · 2026
    11. Advancements in research on the immune-inflammatory mechanisms mediated by NLRP3 inflammasome in ischemic stroke and the regulatory role of natural plant products Frontiers in Pharmacology · 2024 · 18 citations
    12. NFAT5 mediates hypertonic stress-induced atherosclerosis via activating NLRP3 inflammasome in endothelium Cell Communication and Signaling · 2019 · 50 citations
    13. Matrix remodelling and MMP expression/activation are associated with hidradenitis suppurativa skin inflammation Experimental Dermatology · 2019 · 51 citations
    14. Hidradenitis Suppurativa as a Potential Subtype of Autoinflammatory Keratinization Disease Frontiers in immunology · 2020 · 41 citations
    15. Double-stranded RNA induces inflammation via the NF-κB pathway and inflammasome activation in the outer root sheath cells of hair follicles Scientific reports · 2017 · 22 citations
    16. ADSCs inhibit photoaging‐ and photocarcinogenesis‐related inflammatory responses and extracellular matrix degradation Journal of Cellular Biochemistry · 2019 · 19 citations
    17. Umbilical cord mesenchymal stem cell-derived apoptotic extracellular vesicles ameliorate cutaneous wound healing in type 2 diabetic mice via macrophage pyroptosis inhibition Stem cell research & therapy · 2023 · 4 citations
    18. Aberrant inflammasome activation as a driving force of human autoimmune skin disease Frontiers in immunology · 2023 · 3 citations
    19. Smart Fluids As Autophagy-Activating Photoprotectors: In Vitro Analysis of Dead Sea Water and Magnetized Saline Water Against Ultraviolet B (UVB)-Induced Photodamage in Human Keratinocytes Cureus · 2025 · 1 citations
    20. Disrupted citric acid metabolism inhibits hair growth Journal of dermatology · 2022 · 1 citations
    21. Inflammasome Proteins as Biomarkers of Injury and Disease Springer eBooks · 2014
    22. Leek-Derived Exosome-like Nanoparticles Inhibit Hair Growth by Controlling the Differentiation Fate of Hair Follicle Stem Cells ACS Applied Bio Materials · 2026
    23. Fermented Yeast Complex Extract Promotes Hair Regrowth by Decreasing Oxidative Stress Antioxidants · 2025
    24. 1330 The possible role of PTEN-induced kinase 1-mediated mitophagy by regulating inflammasome activation in the pathogenesis of alopecia areata 2023
    25. Baricitinib Attenuates IFN-γ and Polyinosinic:polycytidylic Acid‒Induced Mitochondrial Damage and Inflammasome Activation in Human Keratinocytes Journal of Investigative Dermatology · 2022
    26. Acne-Associated Syndromes Springer eBooks · 2019
    27. The role of skin macrophages under conditions of stress and injury: ultraviolet irradiation and wound healing 2018
    28. 642 Uncovering the role of UV exposure history and genetics in determining skin sun damage Journal of Investigative Dermatology · 2016 · 1 citations
    29. 646 SOX4 is essential for melanoma tumorigenesis Journal of Investigative Dermatology · 2016
    30. The crosstalk between PTEN ‐induced kinase 1‐mediated mitophagy and the inflammasome in the pathogenesis of alopecia areata Experimental Dermatology · 2023 · 6 citations