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    Glossary Neurotrophins

    proteins that support neuron growth, survival, and function

    Neurotrophins are a family of proteins that play a crucial role in the growth, survival, and maintenance of neurons, which are the cells responsible for transmitting information in the nervous system. They help support the health of nerve cells and are involved in processes like learning and memory. For professionals, key members of this family include nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF).

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    Research 30 of 915

    1. Differential dependency of unmyelinated and A delta epidermal and upper dermal innervation on neurotrophins, trk receptors, and p75LNGFR. PubMed · 1998 · 122 citations
    2. Epithelial growth control by neurotrophins: leads and lessons from the hair follicle Progress in brain research · 2004 · 99 citations
    3. A role for p75 neurotrophin receptor in the control of apoptosis‐driven hair follicle regression The FASEB Journal · 2000 · 96 citations
    4. Overexpression of neurotrophin 4 in skin enhances myelinated sensory endings but does not influence sensory neuron number The Journal of Comparative Neurology · 2006 · 34 citations
    5. p75 Neurotrophin Receptor Antagonist Retards Apoptosis-driven Hair Follicle Involution (Catagen) Journal of Investigative Dermatology · 2003 · 24 citations
    6. Retardation of Hair Follicle Development by the Deletion of TrkC, High-Affinity Neurotrophin-3 Receptor Journal of Investigative Dermatology · 1999 · 14 citations
    7. Inhibitory Effects of Polyacetylene Compounds from <i>Panax ginseng</i> on Neurotrophin Receptor-Mediated Hair Growth Biological & Pharmaceutical Bulletin · 2017 · 7 citations
    8. Neurotrophic Effects of Silibinin on Differentiation of Hair Follicle Stem Cells to Neurons DOAJ (DOAJ: Directory of Open Access Journals) · 2010 · 1 citations
    9. Neuroprotective and immunomodulatory effects of human hair follicle stem cells on streptozotocin-induced memory impairment in rats: insights into inflammation and neurotrophic mechanisms 2025
    10. Psychological stress impact neurotrophic factor levels in patients with androgenetic alopecia and correlated with disease progression World Journal of Psychiatry · 2024
    11. Neurotrophic Effects of Silibinin on Differentiation of Hair Follicle Stem Cells to Neurons DOAJ (DOAJ: Directory of Open Access Journals) · 2012
    12. The relationship between psychological distress and neurotrophins in patients with alopecia areata: A crosssectional study TURKDERM · 2025
    13. Female Pattern Hair Loss and Negative Psychological Impact: Possible Role of Brain-derived Neurotrophic Factor (BDNF) Dermatology practical & conceptual · 2023
    14. Neurotrophins, nociceptors, and pain Microscopy Research and Technique · 1999 · 189 citations
    15. Neurotrophin-4 modulates the mechanotransducer Cav3.2 T-type calcium current in mice down-hair neurons Biochemical journal · 2011 · 11 citations
    16. Brain-derived nerve factor and neurotrophins in androgenetic alopecia British Journal of Dermatology · 2011 · 10 citations
    17. Effects of Hura crepitans and Its Active Ingredient, Daphne Factor F3, on Dihydrotestosterone-Induced Neurotrophin-4 Activation and Hair Retardation Biological & Pharmaceutical Bulletin · 2012 · 5 citations
    18. 186 Dissecting the role of the common neurotrophin receptor CD271 in the skin: generation and characterization of a novel mouse model with keratinocyte-specific conditional deletion 2022
    19. Inhibitory Effects of Polyacetylene Compounds from Panax ginseng on Neurotrophin Receptor-Mediated Hair Growth Institutional Repositories DataBase (IRDB) · 2017
    20. ‘Neurotrophology’ of the hair follicle: neurotrophins act as auto‐ and paracrine growth factors and immunomodulators Experimental dermatology · 2006
    21. GDNF neurotrophic factor signaling determines the fate of dermal fibroblasts in wound‐induced hair neogenesis and skin regeneration Experimental Dermatology · 2022 · 2 citations
    22. [Construction and identification of mouse model with conditional knockout of p75 neurotrophin receptor gene in epidermal cells by Cre-loxP system]. PubMed · 2019 · 1 citations
    23. Control of Human Hair Growth by Neurotrophins: Brain-Derived Neurotrophic Factor Inhibits Hair Shaft Elongation, Induces Catagen, and Stimulates Follicular Transforming Growth Factor β2 Expression Journal of Investigative Dermatology · 2005 · 64 citations
    24. Histone deacetylase inhibitors promote neurosteroid‐mediated cell differentiation and enhance serotonin‐stimulated brain‐derived neurotrophic factor gene expression in rat C6 glioma cells Journal of Neuroscience Research · 2009 · 35 citations
    25. Expression patterns of the glial cell line–derived neurotrophic factor, neurturin, their cognate receptors GFRα-1, GFRα-2, and a common signal transduction element c-Ret in the human skin hair follicles Journal of The American Academy of Dermatology · 2008 · 18 citations
    26. Reduced serum brain-derived neurotrophic factor&nbsp;in patients with first onset vitiligo Neuropsychiatric Disease and Treatment · 2014 · 9 citations
    27. Serum brain‐derived neurotrophic factor and vitamin D: Two concordant players controlling depression among alopecia areata and vitiligo patients: A case–control study Journal of Cosmetic Dermatology · 2023 · 6 citations
    28. Evaluation of serum brain-derived neurotrophic factor to assess the association between psoriasis and depression Journal of the Egyptian Women's Dermatologic Society (Print) · 2015 · 2 citations
    29. Correlation between serum brain-derived neurotrophic factor level and depression severity in alopecia areata patients International Journal of Health Sciences · 2022 · 1 citations
    30. Assessment of Serum Level of Brain-Derived Neurotrophic Factor (BDNF) In Pediatric Alopecia Areata: A Case - Control Study 2025