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The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

PCOS is common among Chinese women of reproductive age and linked to serious metabolic and reproductive issues, especially in obese women.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Fullerenes show potential in skin care but need more safety research.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.

The document concludes that specific itchy skin diseases during pregnancy have varying fetal risks and treatments, including corticosteroids and other medications.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Hair loss from hormone therapy in breast cancer patients can be improved with minoxidil treatment.

Alisertib was found to be an effective and tolerable treatment for children with recurrent brain tumors.

Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

Vitamin D receptor is crucial for starting hair growth after birth.