research 504 Angiogenic capabilities driven by dermal papilla cells and their modulation by androgen action
Androgens reduce hair growth by affecting cell differentiation and blood vessel formation.
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This study found that GPC1 is a key regulator of angiogenesis in hair follicles and may be an interesting target for addressing alopecia in dermatology research.
research The regenerative potential of skin and the immune system
This paper explores the complex immune processes and cellular diversity that enable the skin to heal and resist invasion, and highlights its potential as a model for studying regeneration.
research The application of local hypobaric pressure — A novel means to enhance macromolecule entry into the skin
This study found that applying controlled hypobaric stress to the skin significantly improved the in vitro and in vivo penetration of macromolecules, facilitating enhanced drug delivery.
research 192 MicroRNAs and their regulatory interactions in the human hair follicle
This study explored the role of nine specific miRNAs in human hair follicles, revealing significant miRNA/mRNA correlations for miR-24, miR-31, and miR-106a and identifying target genes involved in hair biology.
research The role of VEGF and thrombospondins in skin angiogenesis
This review explores mechanisms of skin angiogenesis and suggests targeting blood vessels as a promising therapy for skin diseases, but it reports no new research results.
research Fibroblast state switching orchestrates dermal maturation and wound healing
This study found that fibroblast behavior switching between proliferation and ECM deposition is vital for dermal architecture, where cell migration is primarily important for tissue repair during wound healing.
research ‘Vasculitis‐like’ damage due to micropunch in follicular unit excision hair transplantation surgery: Ten cases
Hair transplant surgery using micropunch can cause blood vessel damage similar to vasculitis in some cases.
research Formation of actin mesh structures and alpha-smooth muscle actin dynamics in fibroblasts contribute to dermal regeneration in mouse fetus
This study observed that in mouse fetuses, reticular contraction by actomyosin is involved in dermal regeneration, and differences in actin and α-SMA localization may determine the switch between regeneration and scar formation, suggesting potential insights for wound regeneration therapy.
research Investigation of age-related decline of microfibril-associated glycoprotein-1 in human skin through immunohistochemistry study
This study found that levels of the protein MAGP-1, important for skin elasticity, decrease with aging and photoexposure, potentially contributing to skin fragility, sagging, and enlarged pores.