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    Did you mean Epithelial-Mesenchymal Interactions?
    Glossary Epithelial-Mesenchymal Interactions

    complex communication between surface-lining cells and loosely organized cells

    Epithelial-Mesenchymal Interactions (EMI) refer to the complex communication between epithelial cells, which line surfaces and cavities of the body, and mesenchymal cells, which are more loosely organized and can differentiate into a variety of cell types. These interactions are crucial for processes like embryonic development, wound healing, and the formation of hair follicles, as they help coordinate cell behavior and tissue formation.

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    1. Mesenchymal–epithelial interactions during hair follicle morphogenesis and cycling Seminars in Cell & Developmental Biology · 2012 · 300 citations
    2. Role of Androgen in Mesenchymal Epithelial Interactions in Human Hair Follicle Journal of Investigative Dermatology Symposium Proceedings · 2005 · 67 citations
    3. Mechanical force drives the initial mesenchymal-epithelial interaction during skin organoid development Theranostics · 2023
    4. In vitro mesenchymal–epithelial interaction facilitates de novo hair follicle formation Journal of dermatological science · 2016
    5. Strategies to enhance epithelial–mesenchymal interactions for human hair follicle bioengineering Journal of Dermatological Science · 2013 · 57 citations
    6. Mitochondrial Function in Murine Skin Epithelium Is Crucial for Hair Follicle Morphogenesis and Epithelial–Mesenchymal Interactions Journal of Investigative Dermatology · 2015 · 56 citations
    7. 09-P006 Epithelial–mesenchymal interactions promote hair follicle neogenesis and a new stem cell niche in adult corneal epithelium Mechanisms of Development · 2009
    8. Regulation of Keratin 9 in Nonpalmoplantar Keratinocytes by Palmoplantar Fibroblasts Through Epithelial–Mesenchymal Interactions 1999 · 92 citations
    9. Molecular Control of Epithelial–Mesenchymal Interactions During Hair Follicle Cycling 2003 · 277 citations
    10. A Human Folliculoid Microsphere Assay for Exploring Epithelial– Mesenchymal Interactions in the Human Hair Follicle 2008 · 71 citations
    11. Stress-induced premature senescence of dermal papilla cells compromises hair follicle epithelial-mesenchymal interaction Journal of Dermatological Science · 2017 · 35 citations
    12. Induction of Hard Keratin Expression in Non-Nail-Matrical Keratinocytes by Nail-Matrical Fibroblasts through Epithelial-Mesenchymal Interactions Plastic & Reconstructive Surgery · 2003 · 25 citations
    13. Epithelial-Mesenchymal Interaction in Hair Regeneration and Skin Wound Healing Frontiers in Medicine · 2022 · 5 citations
    14. Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle PLoS biology · 2005 · 417 citations
    15. 255 Bone morphogenetic proteins are critical factors for hair follicle epithelial–mesenchymal interactions in androgenetic alopecia Journal of Investigative Dermatology · 2017
    16. Ex Vivo Organ Culture of Human Hair Follicles: A Model Epithelial–Neuroectodermal–Mesenchymal Interaction System Methods in molecular biology · 2010 · 13 citations
    17. BONE MORPHOGENETIC PROTEINS ARE CRITICAL FACTORS FOR HAIR FOLLICLE EPITHELIAL –MESENCHYMAL INTERACTIONS IN ANDROGENETIC ALOPECIA 2017
    18. Demonstration of early anagen-specific stimulatory factors within skin tissue for in vitro mesenchymal-epithelial interaction in collagen embedded hair follicle mixed culture Journal of Dermatological Science · 1993
    19. Generation of bioengineered feather buds on a reconstructed chick skin from dissociated epithelial and mesenchymal cells Development Growth & Differentiation · 2016 · 10 citations
    20. Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice. The EMBO Journal · 1993 · 265 citations
    21. Biological actions of oligomeric procyanidins: Proliferation of epithelial cells and hair follicle growth 2001 · 8 citations
    22. Tgm2/Gh, Gbx1 and TGF-beta are involved in retinoic acid-induced transdifferentiation from epidermis to mucosal epithelium The International Journal of Developmental Biology · 2011 · 14 citations
    23. Hair Germ Model In Vitro via Human Postnatal Keratinocyte-Dermal Papilla Interactions: Impact of Hyaluronic Acid Stem cells international · 2017 · 42 citations
    24. Interfollicular epidermal stem-like cells for the recreation of the hair follicle epithelial compartment Stem cell research & therapy · 2021 · 14 citations
    25. Onset of Keratin 17 Expression Coincides with the Definition of Major Epithelial Lineages during Skin Development The Journal of Cell Biology · 1998 · 318 citations
    26. 592 Cross-interactions of BMP and WNT signaling pathways attenuate androgen effect on HFSC differentiation Journal of Investigative Dermatology · 2019
    27. Spatiotemporal atlas resolves the mesenchymal-epithelial stem cell axis governing human hair follicle aging and pathology bioRxiv (Cold Spring Harbor Laboratory) · 2026
    28. Heterotypic cell contacts and basal lamina morphology during hair follicle development in the mouse: a light, scanning, and electron microscopic study at the site of tissue interaction Canadian journal of zoology · 1983 · 13 citations
    29. Beauty is skin deep: the fascinating biology of the epidermis and its appendages. PubMed · 2000 · 65 citations
    30. The hair growth promoting effect of ascorbic acid 2-phosphate, a long-acting Vitamin C derivative Journal of Dermatological Science · 2006 · 33 citations