January 2013 in “Liaoning Zhongyiyao Daxue xuebao” This study found that Rhizoma Zingiberis Recens significantly activated hair growth in C57BL/6J mice by increasing melanin and promoting hair follicle growth.
This study observed that the extract of Ginseng Radix et Rhizoma promoted hair growth in C57BL/6J mice by enhancing local perfusion and inhibiting platelet aggregation.
September 2012 in “British Small Animal Veterinary Association eBooks” This article discusses pigmentation disorders in veterinary dermatology, focusing on the role of melanogenic pigmentation, and reports no new research results.
April 2012 in “J. Willard Marriott Library” This study concluded that THC and THCA incorporate into hair by a mechanism independent of hair pigmentation, likely influenced by indirect deposition via sebum and skin.
This study found that while there are some ethnic differences in skin and hair follicle characteristics, these differences are unlikely to significantly affect the penetration of topical substances, suggesting other factors such as cultural habits may also play a role.
November 2011 in “Journal of Investigative Dermatology” TRH in hair follicles can influence hair color by increasing melanin.
This laboratory study observed that Prunus Tomentosa Thumb Total Flavone significantly promoted hair growth and follicle maturation in a C57BL 6 mouse model of hair loss.
February 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This research identified fluphenazine as a novel agent that induced hair growth in mice, with iloprost further enhancing this effect, through gene expression analysis and connectivity mapping.
January 2010 in “Chinese Journal of Aesthetic Medicine” The study observed increased melanin and signs of skin aging in melasma-afflicted skin, with strong CK10 expression in the upper basal epidermis, potentially linked to excessive epidermal cell differentiation and aging.
January 2010 in “Pharmacy Today” This study found that collagen and its compound may have antioxidant effects and reduce melanin in guinea pigs, while increasing skin moisture and hydroxyproline content in mice.
March 2009 in “Chinese Journal of Dermatology” This study observed that melanocytes in the outer root sheath of fetal scalp hair follicles may act as stem cells, showing rapid proliferation but immature function and morphology in culture.
January 2009 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” This review discusses various methods of light-based hair removal and reports no new clinical results, highlighting advances in laser and intense pulsed light technologies used for targeting hair pigmentation.
January 2008 in “Linchuang pifuke zazhi” This study found that betamethasone increased tyrosinase activity and melanin content in amelanotic melanocytes from human hair follicles, suggesting a potential mechanism for glucocorticoid treatment in vitiligo.
March 2007 in “International Journal of Cosmetic Science” This study found that Indian and Chinese black hair, with higher melanin content, resist photochemical degradation better than European hair, which has lower melanin levels, when exposed to dry, hot climates.
January 2006 in “Carl von Ossiezky University of Oldenburg” This study observed that unpigmented keratinocytes saturate quickly with foreign substance uptake compared to pigmented melanocytes, where melanin significantly enhances binding.
This study found that the hair of a 16th-century female mummy discovered in Paju was remarkably well-preserved due primarily to a calcium-based surface coating that likely inhibited moisture and microorganism infiltration.
January 2004 in “Banca y finanzas: Revista profesional de gestión financiera” This study found that 5 alpha-dihydrotestosterone increased pigmentation in dorsal spots and scrotal skin of prepubertal male Syrian hamsters, while estradiol decreased scrotal skin melanocytes and reversed androgen-induced pigmentation in costovertebral spots.
This study reported the first documented case of congenital hypotrichosis in a white-tailed deer, based on histologic examination of a fawn collected in South Dakota.
January 2003 in “Linchuang pifuke zazhi” This study used atomic force microscopy to image surface structures of human epidermal melanocytes, hair follicle amelanotic melanocytes, and mouse melanoma cells, revealing differences in branch structure and granule distribution.
January 1999 in “Journal of the European Academy of Dermatology and Venereology” RAPK is a rare skin disorder with pigmented spots, mainly on hands and feet, starting in youth.
January 1990 in “Springer eBooks” Some chemicals can permanently or temporarily remove color from skin and hair, which can be distressing and is not well-regulated in cosmetics.
January 1989 in “Clinical and Experimental Dermatology” This symposium abstract reports no new experimental results and discusses the pathophysiology of hair growth as presented at an event organized by the Institute of Dermatology.
This study reviewed various dermatological conditions associated with oral contraceptive use, highlighting increased pigmentation, decreased sebum production, and changes in hair growth, among other effects.
April 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study suggests that polygonum multiflorum may treat androgenic alopecia by mediating the PI3K/Akt pathway to regulate apoptosis, inhibit inflammation and oxidative stress, and induce melanin production.
18 citations
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February 2017 in “Journal of Cosmetic Dermatology” This study reports that mesotherapy for androgenetic alopecia may paradoxically lead to hair loss and scarring, highlighting the need for improved regulation and monitoring of this treatment.
October 2025 in “Journal of Cosmetic Dermatology” This study found that conventional treatments like oral dutasteride and topical/oral minoxidil are effective for male androgenetic alopecia, and it provides guidance on the relative efficacy of some alternative treatments, such as topical melatonin and rosemary oil, compared to these conventional therapies.
127 citations
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November 2010 in “Pigment cell & melanoma research” This article discusses the challenges in hair follicle pigmentation research compared to epidermal melanocytes and highlights the limitations of relying on mouse models, but reports no new experimental findings.
82 citations
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January 1997 in “Forensic science international” This article presents a biochemical model to explain how drug molecules are incorporated into hair, highlighting factors such as drug melanin affinity and the role of physico-chemical properties.
38 citations
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June 2005 in “Acta Biochimica Polonica” This study found that spleens of black C57BL/6 mice contain eumelanin, with properties different from skin and hair melanin, and may originate from skin melanin transported by immune cells.
25 citations
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October 2012 in “Dermatologic clinics” This article reviews the principles and practical considerations of laser and light-based hair removal techniques, but it does not report new clinical findings.