3 citations
,
March 2008 in “Medical laser application” This review highlights recent advances in laser treatments for skin disorders, including the optimization of vascular lesion treatment and improved safety for hair removal, but reports no new results.
1 citations
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January 2009 in “Elsevier eBooks” This review discusses the mechanisms of laser and IPL hair removal, particularly for darker skin types, and reports no new findings, highlighting potential adverse effects like pigmentation changes or scarring with improper use.
June 2026 in “International Journal of Drug Delivery Technology” This review explores the potential of herbal therapies and modern delivery methods for managing premature hair greying, highlighting promising plant-based treatments and emphasizing the need for clinical trials to validate their effectiveness.
October 2025 in “International Journal of Research in Dermatology” This review highlights the benefits of long-pulsed Nd:YAG lasers for hair removal in individuals with Fitzpatrick skin types IV-VI, offering deeper follicular targeting with reduced melanin interaction, and examines emerging technologies like radiofrequency and RF microneedling for safe treatment options in skin of color.
January 2019 in “International Journal of Plant Animal and Environmental Sciences” This study found that a 50% ethanol extract from marine green alga Chlamydomonas sp. W80 exhibited several bioactive properties, including skin lightening and hair growth promotion effects, with potential implications for bioenergy and high-value coproducts.
March 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that HairTime, a novel non-invasive assay using hair samples, accurately estimates chronotype and reveals its plasticity influenced by work schedules and lifestyle factors.
8 citations
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June 2022 in “International Journal of Molecular Sciences” This review discusses the potential of extracellular vesicles for facial aesthetic applications, including scar reduction and skin rejuvenation, but reports no new clinical results; further research into production and mechanisms is needed.
July 2019 in “Journal of the Formosan Medical Association” Melatonin may help with nerve pain, a hepatitis C drug is effective but has side effects, a treatment for mouth sores works but can cause blood issues, ear reconstruction with an implant is safe, HIV transmission from mother to child in Taiwan is now 0% with treatment, certain blood problems are more common in people with a tongue condition, a gene and being overweight are linked to hair loss in some women, a new technique could reduce radiation for lung nodule patients, a hepatitis treatment may lower cancer recurrence after a procedure, and adding extra screening improves tuberculosis detection in patients with lung infections.
January 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This article reviews melatonin's roles, including regulating sleep and mitigating oxidative stress, and reports no new research findings.
3 citations
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November 2022 in “Frontiers in Oncology” This review discusses the role of melanin synthesis in melanoma, focusing on how melanosomal pH might regulate melanin production, and reports no new results.
96 citations
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January 1997 in “Clinics in Dermatology” This study found that G protein-coupled estrogen receptor enhances melanin synthesis in melanoma cells through cAMP-PKA-MITF-TYR signaling, suggesting its potential as a drug target for chloasma treatment.
7 citations
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January 1995 in “The Indian Journal of Animal Sciences” This study observed that buffalo teats have a melanin-rich epidermis, no hair follicles, and a complex structure with specific epithelial and muscular characteristics.
November 2025 in “Frontiers in Veterinary Science” In this study, feeding H-line chickens a diet with 1.0% tyrosine for 40 days significantly increased melanin deposition in feathers and revealed changes in gene expression related to melanin pathways, suggesting tyrosine's involvement in regulating feather color through the EDNRB2 regulatory network.
June 2024 in “Molecules/Molecules online/Molecules annual” This study found that Platycladus orientalis flavonoids may reduce oxidative damage and slow melanin degradation in AGA-affected hair, improving its quality.
January 2000 in “Optics Letters” This study found that the maximum infrared temperature of laser-irradiated hair depends on melanin type, with eumelanin-rich hair reaching higher temperatures than pheomelanin-containing hair.
November 2025 in “PLoS ONE” This study observed that albino rats, despite not producing melanin, have melanocytes localized in specific skin areas of their hair matrix, suggesting that gene expression analysis of their skin should consider regional differences in melanocyte presence.
70 citations
,
December 2004 in “Proceedings of the National Academy of Sciences” This study found that BMP signaling influences hair pigmentation in mice by affecting the Agouti protein and interacts with MC-1R pathways to modulate melanin production.
9 citations
,
October 1976 in “Journal of Cutaneous Pathology” This study observed that human growth hormone treatment in osteoporosis patients appeared to improve skin thickness and restore dermal structures towards normal without stimulating hair, sebum, or melanin.
2 citations
,
January 2017 in “Journal of Pigmentary Disorders” This study explores the complex and not yet fully understood causes of premature hair greying, noting genetic factors such as Pax3 and MITE genes, potential defects in melanin transfer, and associations with certain syndromes, while stating that effective treatments are currently lacking.
June 2025 in “Animal Bioscience” This study found that miRNA-24 downregulates the KLF6 gene, influencing coat color by affecting melanogenesis pathways in Cashmere goats, and that miRNA-24 inhibition increased melanin content in mice.
March 2025 in “Animal Bioscience” In this study, researchers conducted a whole-transcriptome analysis of Dazu Black Goats and Inner Mongolia Cashmere Goats to explore differences in hair follicle development and melanin production, revealing variations in hair characteristics and 640 differentially expressed RNAs that could inform goat breeding and textile applications.
December 2023 in “Clinical, cosmetic and investigational dermatology” This study found that specific dermoscopic signs, such as diameter diversity of leukotrichia and Pohl-Pinkus constrictions, were associated with progressive vitiligo, and early-stage melanin synthesis was impaired in vitiligo-associated leukotrichia.
In this study, mangosteen pericarp extract was found to promote hair dermal papilla cell proliferation and enhance melanin synthesis, suggesting its potential as an ingredient in hair growth and tanning products.
This review discusses the factors influencing human hair color, including genetic components and enzymatic activity, and highlights the forensic significance of hair color analysis, but reports no new findings.
25 citations
,
August 2015 in “Molecules” This study found that mimosine dipeptide enantiomers inhibit melanogenesis and cyclooxygenase enzymes in B16F10 melanoma cells, suggesting potential for treating skin hyperpigmentation and inflammation.
14 citations
,
October 2020 in “Scientific reports” This study found that ATM protein plays a crucial role in protecting human hair follicle melanocytes from oxidative stress, which is linked to the greying of hair.
241 citations
,
March 2000 in “The Journal of Urology” This review discusses the concept of andropause, preferring the term "androgen decline in the aging male" (ADAM), and emphasizes the need for urologists to recognize its manifestations and manage its treatment, but reports no new clinical results.
12 citations
,
September 2022 in “Foods” This review discusses the potential role of nutraceuticals in preventing and treating COVID-19 and post-COVID syndrome, but reports no new clinical findings; the authors highlight the need for further research.
11 citations
,
May 2021 in “Journal of Cosmetic Dermatology” This review discusses the potential use of platelet-rich plasma for treating melasma, suggesting its effectiveness but noting the need for more extensive studies to confirm these findings.
1 citations
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October 2010 in “Pediatrics in review” This article discusses the integration of complementary and alternative medicine (CAM) therapies in the treatment of eating disorders but presents no new clinical findings.