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    Glossary Melatonin Receptors

    proteins that bind melatonin to regulate sleep and other functions

    Melatonin receptors are proteins found in various parts of the body, including the brain and skin, that bind to the hormone melatonin. These receptors help regulate sleep-wake cycles, mood, and even hair growth by influencing cellular activities in response to melatonin.

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    1. Melatonin membrane receptors in peripheral tissues: Distribution and functions Molecular and Cellular Endocrinology · 2012 · 506 citations
    2. The murine hair follicle is a melatonin target Experimental dermatology · 2004
    3. Activity evaluation of epidermo-melanin unit and dermal damage in melasma UNESP Institutional Repository (São Paulo State University) · 2016
    4. Inhibition of prolactin promotes secondary skin follicle activation in cashmere goats 2021 · 7 citations
    5. Melatonin Receptors and Their Role in Human Diseases Springer eBooks · 2013 · 4 citations
    6. A role of melatonin in neuroectodermal‐mesodermal interactions: the hair follicle synthesizes melatonin and expresses functional melatonin receptors ˜The œFASEB journal · 2005 · 122 citations
    7. Melatonin and the hair follicle Journal of pineal research · 2007 · 109 citations
    8. Melatonin promotes Cashmere goat (<i>Capra hircus</i>) secondary hair follicle growth: a view from integrated analysis of long non-coding and coding RNAs Cell Cycle · 2018 · 32 citations
    9. Melatonin supplement induced the hair follicle development in offspring rex rabbits Journal of Animal Physiology and Animal Nutrition · 2020 · 9 citations
    10. Melatonin regulates the periodic growth of secondary hair follicles through the nuclear receptor RORα Frontiers in Veterinary Science · 2023
    11. A Study on Melatonin Receptor Genes Expression in Embryonic Goose Skin Feather Follicles Indian Journal of Animal Research · 2022
    12. On the Role of Melatonin in Skin Physiology and Pathology Endocrine journal · 2005 · 222 citations
    13. α-Mangostin, a safe and natural product as a candidate skin-whitening agent Scientific Reports · 2025
    14. A discourse on human hair fibers and reflections on the conservation of drug molecules International Journal of Legal Medicine · 1996 · 47 citations
    15. Melanocytes and Vitiligo (and Hair Graying) Elsevier eBooks · 2014 · 1 citations
    16. Melatonin promotes hair regeneration by modulating the Wnt/β‐catenin signalling pathway Cell proliferation · 2024
    17. The cutaneous serotoninergic/melatoninergic system: securing a place under the sun ˜The œFASEB journal · 2005 · 349 citations
    18. Chronic Stress Suppresses the Expression of Cutaneous Hypothalamic–Pituitary–Adrenocortical Axis Elements and Melanogenesis PLoS ONE · 2014 · 40 citations
    19. The Retinoic-Acid-Related Orphan Receptor Alpha May Be Highly Involved in the Regulation of Seasonal Hair Molting International Journal of Molecular Sciences · 2025
    20. Keratinocytes regulate the function of melanocytes 2014 · 55 citations
    21. Effects of Baicalin on Alopecia and the Associated Mechanism BioMed Research International · 2022 · 2 citations
    22. Effects of short photoperiod on cashmere growth, hormone concentrations and hair follicle development-related gene expression in cashmere goats Journal of applied animal research · 2023
    23. Hair Follicle Pigmentation 2005 · 450 citations
    24. Melatonin: functions and ligands Drug discovery today · 2014 · 160 citations
    25. Peer Review #1 of "Melatonin increases growth properties in human dermal papilla spheroids by activating AKT/GSK3β/β-Catenin signaling pathway (v0.1)" 2022
    26. Peer Review #2 of "Melatonin increases growth properties in human dermal papilla spheroids by activating AKT/GSK3β/β-Catenin signaling pathway (v0.1)" 2022
    27. Melatonin in the skin: synthesis, metabolism and functions Trends in Endocrinology and Metabolism · 2008 · 252 citations
    28. Melatonin and hair physiology: reasons and clinical efficacy data as a topical treatment of androgenic alopecia Medicina cutánea ibero-latino-americana · 2014
    29. The Physiological Impact of Melatonin, Its Effect on the Course of Diseases and Their Therapy and the Effect of Magnetic Fields on Melatonin Secretion—Potential Common Pathways of Influence Biomolecules · 2024 · 3 citations
    30. Mechanism of action and promising clinical application of melatonin from a dermatological perspective Journal of Translational Autoimmunity · 2023 · 15 citations