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    Glossary MAPK pathway

    crucial cell signaling mechanism regulating growth, division, and stress response

    The MAPK pathway, or Mitogen-Activated Protein Kinase pathway, is a crucial signaling mechanism in cells that helps regulate various activities such as growth, division, and response to stress. It involves a series of proteins that communicate signals from the cell surface to the DNA in the nucleus, ultimately influencing gene expression and cellular behavior. This pathway is significant in many biological processes and is often studied in the context of diseases like cancer and conditions affecting hair growth, such as alopecia.

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    1. Involvement of Activation of Mitogen-Activated Protein Kinase (MAPK)/Extracellular Signal-Regulated Kinase (ERK) Signaling Pathway in Proliferation of Urethral Plate Fibroblasts in Finasteride-Induced Rat Hypospadias Medical Science Monitor · 2018 · 10 citations
    2. Quercitrin Stimulates Hair Growth with Enhanced Expression of Growth Factors via Activation of MAPK/CREB Signaling Pathway Molecules · 2020 · 25 citations
    3. Reductive Stress Selectively Disrupts Collagen Homeostasis and Modifies Growth Factor-independent Signaling Through the MAPK/Akt Pathway in Human Dermal Fibroblasts Molecular & cellular proteomics · 2019 · 9 citations
    4. Hair growth‐promotion effects of different alternating current parameter settings are mediated by the activation of Wnt/<i>β</i>‐catenin and MAPK pathway Experimental Dermatology · 2015 · 27 citations
    5. Insulin-like Growth Factor 1 (IGF-1) in Hair Regeneration: Mechanistic Pathways and Therapeutic Potential Current Issues in Molecular Biology · 2025
    6. Mathematical Modeling and Inference of Epidermal Growth Factor-Induced Mitogen-Activated Protein Kinase Cell Signaling Pathways International Journal of Molecular Sciences · 2024 · 3 citations
    7. Large extracellular vesicles from induced pluripotent stem cell-marrow stem cells enhance limb angiogenesis via ERK/MAPK Nanomedicine · 2024 · 1 citations
    8. Epimedium brevicornum Maxim. Extract exhibits pigmentation by melanin biosynthesis and melanosome biogenesis/transfer Frontiers in pharmacology · 2022 · 6 citations
    9. 691 Topical curcumin promotes induction of the murine hair cycle 2016 · 3 citations
    10. Bio-Nanovesicle-Based Approaches for Hair and Skin Regeneration: An Updated Concise Review Cells · 2026
    11. Identificación de la variación molecular y genética subyacente a las enfermedades de la piel Repository of Digital Objects for Teaching Research and Culture (University of Valencia) · 2025
    12. Rejuvenating senescent hair follicles: a novel conjugated linoleic acid based nanovesicle approach to treat androgenic alopecia Journal of Nanobiotechnology · 2025
    13. Glucagon-like peptide-1 receptor and proglucagon expression in mouse skin Regulatory Peptides · 2006 · 37 citations
    14. Establishment of an Efficient Primary Culture System for Human Hair Follicle Stem Cells Using the Rho-Associated Protein Kinase Inhibitor Y-27632 Frontiers in cell and developmental biology · 2021 · 16 citations
    15. The Photoprotective Effect of S-Methylmethionine Sulfonium in Skin International Journal of Molecular Sciences · 2015 · 14 citations
    16. Recombinant Filaggrin-2 microneedles reverse androgenetic alopecia by rescuing mitochondrial dysfunction in dermal papilla cells International Journal of Biological Macromolecules · 2026
    17. Hair Loss Associated With Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist Use: A Systematic Review Cureus · 2025
    18. Epimorphin and Epithelial Morphogenesis 2007
    19. Inhibition of TNF-α-Induced Collagen Degradation and Oxidative Damage by Centipeda minima and Brevilin A in Human Dermal Fibroblasts Current Issues in Molecular Biology · 2025 · 1 citations
    20. Chemical Constituents from Osmanthus fragrans var. aurantiacus Makino with Their In Vitro and In Silico Studies Target Anti-Inflammation by Suppressing ERK 1/2 MAPK Signaling International Journal of Molecular Sciences · 2025
    21. The potential application of natural products in cutaneous wound healing: A review of preclinical evidence Frontiers in Pharmacology · 2022 · 45 citations
    22. Bisphenol-A antagonizes the rapidly modulating effect of DHT on spinogenesis and long-term potentiation of hippocampal neurons Chemosphere · 2017 · 10 citations
    23. 606 Connecting signaling dynamics with cell fates in live mice Journal of Investigative Dermatology · 2021
    24. Platelet Concentrates Preconditioning of Mesenchymal Stem Cells and Combined Therapies: Integrating Regenerative Strategies for Enhanced Clinical Applications Cell Transplantation · 2024 · 3 citations
    25. Betulinic acid exerts anti‐hepatitis C virus activity via the suppression of NF‐κB‐ and MAPK‐ERK1/2‐mediated COX‐2 expression British Journal of Pharmacology · 2015 · 44 citations
    26. Curcumin and cancer biology: Focusing regulatory effects in different signalling pathways Phytotherapy Research · 2021 · 27 citations
    27. The Role of LncRNAs in Radio- and Chemoresistance of Glioblastoma: Prognostic or Therapeutic? Current Oncology · 2025
    28. Biological therapy in the treatment of melanoma Journal of Mind and Medical Sciences · 2018 · 3 citations
    29. Exosomes derived from Umbilical cord mesenchymal stem cell promote hair regrowth in C57BL6 mice through upregulation of the RAS/ERK signaling pathway Journal of Translational Internal Medicine · 2024
    30. Wnt/β‐catenin and ERK pathway activation: A possible mechanism of photobiomodulation therapy with light‐emitting diodes that regulate the proliferation of human outer root sheath cells Lasers in Surgery and Medicine · 2017 · 43 citations