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    Glossary MAPK pathway

    crucial cell signaling mechanism regulating growth, division, and stress response

    The MAPK pathway, or Mitogen-Activated Protein Kinase pathway, is a crucial signaling mechanism in cells that helps regulate various activities such as growth, division, and response to stress. It involves a series of proteins that communicate signals from the cell surface to the DNA in the nucleus, ultimately influencing gene expression and cellular behavior. This pathway is significant in many biological processes and is often studied in the context of diseases like cancer and conditions affecting hair growth, such as alopecia.

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    1. Quercitrin Stimulates Hair Growth with Enhanced Expression of Growth Factors via Activation of MAPK/CREB Signaling Pathway Molecules · 2020 · 25 citations
    2. Sinapic Acid Promotes Browning of 3T3‐L1 Adipocytes via p38 MAPK/CREB Pathway BioMed Research International · 2020 · 29 citations
    3. Drug Repurposing of Voglibose, a Diabetes Medication for Skin Health Pharmaceuticals · 2025 · 4 citations
    4. Network Pharmacology Reveals Curcuma aeruginosa Roxb. Regulates MAPK and HIF-1 Pathways to Treat Androgenetic Alopecia Biology · 2024
    5. PAK4 signaling in health and disease: defining the PAK4–CREB axis Experimental & Molecular Medicine · 2019 · 81 citations
    6. Novel circRNAs from cashmere goats: Discovery, integrated regulatory network, and their putative roles in the regeneration and growth of secondary hair follicles Czech Journal of Animal Science · 2022 · 7 citations
    7. Transcriptome sequencing reveals the key genes associated with hair follicle development in Qianhua Mutton Merino Frontiers in Veterinary Science · 2025
    8. Polydeoxyribonucleotide (PDRN) salmon sebagai agen anti penuaan Intisari Sains Medis · 2025
    9. Molecular pathology of skin adnexal tumours Histopathology · 2021 · 16 citations
    10. Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration Cell Reports · 2023 · 44 citations
    11. Tribuloside acts on the PDE/cAMP/PKA pathway to enhance melanogenesis, melanocyte dendricity and melanosome transport Journal of ethnopharmacology · 2023
    12. Effects of natural products on skin inflammation caused by abnormal hormones secreted by the adrenal gland Frontiers in Pharmacology · 2023 · 2 citations
    13. Exploring the Efficacy and Potential Mechanisms of Topical Periplaneta americana (L.) Extract in Treating Androgenetic Alopecia in a Mouse Model: A Systems Pharmacology and Skin Microbiome Analysis Biology · 2025
    14. Nerve growth factor regulates the proliferation of cashmere goat outer root sheath cells through the activation of cAMP-binding protein Small ruminant research · 2019 · 1 citations
    15. Activation of cAMP Signaling in Response to α-Phellandrene Promotes Vascular Endothelial Growth Factor Levels and Proliferation in Human Dermal Papilla Cells International journal of molecular sciences · 2022 · 6 citations
    16. Corticotropin releasing hormone and the skin Frontiers in bioscience · 2006 · 137 citations
    17. Xiaozhi Yufa decoction ameliorates androgenetic alopecia through inhibition of MAPK signaling and regulation of lipid metabolism Frontiers in Pharmacology · 2025
    18. Effect of <i>Plantago asiatica L</i>. extract on the anagen phase in human hair follicle dermal papilla cells Journal of Cosmetic Dermatology · 2023 · 5 citations
    19. Gene Expression Profiles of Melanocytes Over-Expressing miR-5110 in Alpaca Current Issues in Molecular Biology · 2026
    20. Cooperation of TGF‐β and FGF signalling pathways in skin development Cell Proliferation · 2023 · 23 citations
    21. Coordinating the Sculptors: Ectodysplasin-A (EDA) Signaling Cross-Talk with Skeletogenic Pathways Preprints.org · 2025
    22. The Role of LncRNAs in Radio- and Chemoresistance of Glioblastoma: Prognostic or Therapeutic? Current Oncology · 2025
    23. Plant‐Derived Monomers for Grey Hair Reversal Through Upregulation of Melanogenesis and Tyrosinase Activity Journal of Cellular and Molecular Medicine · 2025 · 1 citations
    24. Role of the Wnt signaling pathway in keratoacanthoma Cancer reports · 2019 · 2 citations
    25. <i>Malva verticillata</i>seed extracts upregulate the Wnt pathway in human dermal papilla cells International Journal of Cosmetic Science · 2015 · 25 citations
    26. Exosomes derived from Umbilical cord mesenchymal stem cell promote hair regrowth in C57BL6 mice through upregulation of the RAS/ERK signaling pathway Journal of Translational Internal Medicine · 2024
    27. Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways InTech eBooks · 2017 · 1 citations
    28. Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways Journal of Cellular Biochemistry · 2005 · 24 citations
    29. Shikimic acid, a mannose bioisostere, promotes hair growth with the induction of anagen hair cycle Scientific Reports · 2019 · 35 citations
    30. Quercetin promotes production of secondary hair follicle stem cells in cashmere goat: a mechanistic study Frontiers in Veterinary Science · 2025