This literature review suggests that Cyperus rotundus L extract is a promising natural agent for promoting hair growth due to its bioactive compounds and mechanisms of action, but emphasizes the need for further human clinical trials to confirm its safety and effectiveness.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This literature review suggests that Cyperus rotundus L extract shows promise as a natural hair growth agent due to its bioactive compounds and mechanisms that stimulate hair growth, although more human clinical trials are needed to confirm its safety and efficacy.
August 2026 in “Pharmacy Reports” This study found that a nanoemulsion hair spray formula with 25% PEG 400 showed promising physicochemical stability, but further research is needed to assess its colloidal stability and efficacy in hair growth.
April 2025 in “Jurnal Sains dan Teknologi Farmasi Indonesia” This study found that a nanostructured lipid carrier gel containing Minoxidil and Finasteride met desired criteria for stability and performance, suggesting it may be an effective topical treatment for hair loss, especially in extreme conditions.
March 2023 in “Jurnal Ilmiah Medicamento” In this study, herbal hair tonic made from Usada Bali ingredients significantly increased hair growth in mice without causing skin irritation compared to a negative control.
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October 2017 in “International Journal of Applied Pharmaceutics” This study found that hair tonics with 5% and 10% licorice extract promoted hair growth in rabbits similarly to 2% minoxidil and were generally safe, although they caused mild eye irritation at the 2.5% concentration.
January 2026 in “JURNAL PIJAR MIPA” This study found that ethanol extracts from Marygold flowers significantly promote hair growth in male rabbits, with the highest concentration (20%) leading to longer and denser hair compared to lower concentrations.
February 2025 in “Journal of Fundamental and Applied Pharmaceutical Science” In this experimental study, the researchers developed and evaluated a hair tonic made from mangosteen peel extract, finding that all four tested formulations showed suitable physical characteristics and met standard requirements for attributes like pH, viscosity, and stability.
May 2024 in “Molecules/Molecules online/Molecules annual” This narrative review reports that well-selected plant extracts and their active compounds may improve hair health by promoting hair growth and preventing hair loss, potentially aiding in developing targeted therapies for alopecia.
This study evaluated formulations of a nanoemulsion with mangkokan leaves extract and candlenut oil, predicting its effectiveness for enhancing hair growth in male Sprague Dawley rats, with nanoemulsions showing assumed stable physical characteristics after two weeks.
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August 2019 In this study, a hair tonic formulation with 25% ethanol extract of mangkokan leaves showed effectiveness in promoting hair growth, as measured by significant differences in hair length and weight compared to the control.
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November 2017 in “JFL : Jurnal Farmasi Lampung” In this study, researchers found that hair tonic formulations containing Nothopanax scutellarium extract enhanced hair growth in male rabbits over 21 days, with the 25% concentration showing comparable effects to a minoxidil-based positive control.
December 2025 in “eTheses of Maulana Malik Ibrahim State Islamic University (Maulana Malik Ibrahim State Islamic University)” In this laboratory study, the researchers reported that an ethnomedicinal hair growth formula from East Nusa Tenggara, incorporating Kemiri, Kembang sepatu, Beringin, Mangkokan, and Waru, demonstrated significant antioxidant activity and effectively stimulated hair growth, suggesting potential development as a natural cosmeceutical.
June 2025 in “Mutiara Jurnal Penelitian dan Karya Ilmiah” This study observed that using moringa leaf extract in hair tonic reduced hair loss among the sampled students, with the average hair loss decreasing from 118.75 strands to 79.25 strands per day.
July 2018 in “Media Informasi” This study found that a 3:2 combination of pandan leaf and mother-in-law's tongue extracts in hair tonic showed similar hair growth activity as 5% minoxidil after three weeks.
June 2023 in “CHEDS Journal of Chemistry Education and Science” In this experimental study, researchers developed a hair tonic using green spinach leaves and assessed its feasibility based on vitamin content and sensory characteristics, finding that the tonic was generally liked by panelists in hedonic tests.
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March 2019 in “Biodiversitas Journal of Biological Diversity” In this study of duku trees along the Batanghari River in Indonesia, researchers identified traits in mother trees that may help select for resistance to stem canker disease.
December 2025 in “American journal of microbiological research” This study found that Marantochloa species leaves have antimicrobial and anti-inflammatory properties and help preserve the quality of corn-based foods, suggesting their potential nutritional benefits and encouraging their use in Greater Lomé.
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April 2017 in “JURNAL ILMU KEFARMASIAN INDONESIA” This study found that the combination of Pandan Wangi leaves and Noni fruit extracts may inhibit fungi commonly associated with dandruff, suggesting potential use in anti-dandruff shampoo formulations.
June 2024 in “JURNAL BIOLOGI TROPIS” In this systematic literature review, researchers reported that Moringa oleifera Lamk. leaf extract may serve as a potential anti-acne agent, demonstrated by its ability to inhibit the growth of acne-causing bacteria in laboratory settings.
August 2024 in “Faedah Jurnal Hasil Kegiatan Pengabdian Masyarakat Indonesia” In this community outreach, participants in Langkat were educated about the benefits of gotu kola leaves as a natural facial moisturizer, resulting in improved knowledge, especially among children, teenagers, and mothers, as shown by pre- and post-test gains.
May 2020 in “Jurnal Penelitian Perawat Profesional” This literature review identified that katuk leaves, rich in vitamins and phenolic compounds, show potential in preventing hair loss by promoting hair growth, enhancing vascularity, and nourishing hair.
May 2024 in “Jurnal Penelitian Farmasi dan Herbal” In this experimental study on rabbits, the authors concluded that a pomade containing 10% meniran leaf extract was an effective hair growth stimulant and could compete with a positive control, fulfilling the required pomade characteristics.
February 2022 in “World Journal Of Advanced Research and Reviews” This study found that Peperomia pellucida plant extract may benefit hair growth, male libido, male fertility, and renal cell recovery.
October 2025 in “Interdiciplinary Journal and Hummanity (INJURITY)” This study characterized bioactive compounds in extracts from six Kalimantan herbal plants, confirming traditional medicinal uses with findings such as triterpenoids and several potent compounds with antimicrobial and cardiovascular benefits, laying groundwork for potential therapeutic applications and conservation efforts.
July 2024 in “Jurnal Pengabdian Masyarakat Putri Hijau” This study involved educating Dewantara Husada Health Vocational High School students about using meniran leaf extract in pomade formulations as a hair growth stimulant, demonstrating high engagement and interest in the topic.
January 2014 in “UMS Institutional Repository (Universiti Malaysia Sabah)” This study found that Murraya koenigii extracts and compounds demonstrated potent antibacterial and cytotoxic activities, with notable effects against antibiotic-resistant strains and cancer cell lines, supporting its potential for further pharmacological investigation.
August 2019 in “Pharmacoscript” This study found that a 3:2 combination of pandanus and sansevieria leaf extracts showed the best hair growth activity compared to using each extract alone.
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April 2016 in “Pharmaciana” This study found that a combination of 5% green tea leaf extract and 2.5% gotukola extract stimulated hair growth effectively, achieving a growth rate of 2.689 cm in 28 days.
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August 2018 in “Journal of pharmacopolium” This study found that a combination extract of pandanus and sansevieria leaves at a 3:2 ratio showed better hair growth activity than either extract alone.