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The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

About 6.5% of young Caucasian women in Spain have polycystic ovary syndrome.

Removing part of the vitamin D receptor stops vitamin D from working properly.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Androgenetic alopecia in women needs more research and better management strategies.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Early hair loss may indicate risk of insulin resistance.

Finasteride with oral contraceptive helps improve hair loss in premenopausal women.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

To diagnose hair loss, use a systematic approach including history, exams, and tests.