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Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.

Four-amino acid part makes enzyme sensitive to finasteride.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Some chemotherapy can cause permanent hair loss.

Fulvestrant is a well-tolerated new treatment for advanced breast cancer that may delay chemotherapy.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Neurosteroids show promise for treating epilepsy and more research is needed.

Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

Baldness caused by male hormones in female-to-male transsexuals doesn't increase the risk of heart disease.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

Women with PCOS are more likely to have sleep apnea, mainly if they are obese.