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    Glossary Lipid Layer

    thin, oily barrier covering cell surfaces, retaining moisture

    The lipid layer is a thin, oily barrier that covers the surface of cells, including those in the skin and hair. It helps to retain moisture, protect against environmental damage, and maintain the integrity of the cell structure. In the context of hair, the lipid layer contributes to the hair's shine and smoothness by sealing in moisture and reducing friction.

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    1. ToF‐SIMS characterization of the lipid layer on the hair surface. I: the damage caused by chemical treatments and UV radiation Surface and interface analysis · 2010 · 23 citations
    2. Lipid-based nanocarriers coupled with CO 2 laser-mediated drug delivery enhance skin penetration and hair follicle targeting Journal of drug targeting · 2026
    3. The Effect of Particle Size on the Deposition of Solid Lipid Nanoparticles in Different Skin Layers: A Histological Study Advanced Pharmaceutical Bulletin · 2016 · 128 citations
    4. The Effect of Particle Size on the Deposition of Solid Lipid Nanoparticles in Different Skin Layers: A Histological Study. PubMed · 2016 · 71 citations
    5. Investigation of the cutaneous penetration behavior of dexamethasone loaded to nano-sized lipid particles by EPR spectroscopy, and confocal Raman and laser scanning microscopy European journal of pharmaceutics and biopharmaceutics · 2016 · 21 citations
    6. ToF‐SIMS characterization of the lipid layer on the hair surface. II : Effect of the 18‐MEA lipid layer on surface hydrophobicity Surface and interface analysis · 2010 · 19 citations
    7. Association of Early Clinical Response to Laser Rejuvenation of Photoaged Skin with Increased Lipid Metabolism and Restoration of Skin Barrier Function Journal of Investigative Dermatology · 2022 · 11 citations
    8. Integral hair lipid in human hair follicle Journal of dermatological science · 2011 · 36 citations
    9. Integral Lipid in Human Hair Follicle 2005 · 30 citations
    10. Effect of physical stimuli on hair follicle deposition of clobetasol-loaded Lipid Nanocarriers Scientific Reports · 2020 · 52 citations
    11. Adiponectin Signaling Regulates Lipid Production in Human Sebocytes PLoS ONE · 2017 · 32 citations
    12. A systematic review on the lipid composition of human hair International Journal of Dermatology · 2022 · 8 citations
    13. Analysis of Lipids in the Medulla of Japanese Hair and Their Function Cosmetics · 2018 · 7 citations
    14. Influence of Hair Growth Cycle on Lipid Composition of Mouse Epidermis and Dermis. Experimental Biology and Medicine · 1960 · 6 citations
    15. NANOSTRUCTURE LIPID CARRIER TECHNOLOGY IN DRUG DELIVERY: ROUTE OF ADMINISTRATION, PREPARATION METHOD, CHARACTERIZATION, AND APPLICATION FOR ANTI-AGING Medical Sains Jurnal Ilmiah Kefarmasian · 2024
    16. SKIN TARGETING OF AN OPTIMIZED CAFFEINE NANOSTRUCTURED LIPID CARRIER WITH IMPROVED EFFICIENCY AGAINST CHEMOTHERAPY INDUCED ALOPECIA International Journal of Applied Pharmaceutics · 2022
    17. Skin Targeting of An Optimized Caffeine Nanostructured Lipid Carrier With Improved Efficiency Against Chemotherapy Induced Alopecia Research Square (Research Square) · 2021
    18. MALDI (matrix assisted laser desorption ionization) Imaging Mass Spectrometry (IMS) of skin: Aspects of sample preparation Talanta · 2017 · 30 citations
    19. The impact of particle size of nanostructured lipid carriers on follicular drug delivery: A comprehensive analysis of mouse and human hair follicle penetration Bioimpacts · 2024
    20. Follicular delivery of spironolactone via nanostructured lipid carriers for management of alopecia DOAJ (DOAJ: Directory of Open Access Journals) · 2014
    21. Development of Stratum Corneum Lipid Liposomes for Topical Drug Delivery International Journal of Drug Delivery Technology · 2026
    22. The effect of a herbal paste and oil extract on the lipid content of canine hair fibres Veterinary dermatology · 2017 · 2 citations
    23. A discrete transition zone between cuticle and cortex layers of a human hair fibre: changes observed in the presence of breast cancer ecancermedicalscience · 2017 · 1 citations
    24. Epithelial barrier function: assembly and structural features of the cornified cell envelope BioEssays · 2002 · 425 citations
    25. The structure of people’s hair PeerJ · 2014 · 107 citations
    26. Structural analysis of the outermost hair surface using TOF-SIMS with gas cluster ion beam sputtering Biointerphases · 2016 · 11 citations
    27. Influence of particle parameters on deposition onto healthy and damaged human hair International Journal of Cosmetic Science · 2024 · 5 citations
    28. Studies on the efficacy of methyl esters of n-alkyl fatty acids as penetration enhancers Journal of Investigative Dermatology · 1989 · 3 citations
    29. "A Critical Review: Recent Advances in Ethosomal Gel for Transdermal Drug Delivery Systems'' Zenodo (CERN European Organization for Nuclear Research) · 2026
    30. "A Critical Review: Recent Advances in Ethosomal Gel for Transdermal Drug Delivery Systems'' Zenodo (CERN European Organization for Nuclear Research) · 2026