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GlossaryLamotrigine (Lamictal)

medication used to treat epilepsy and bipolar disorder

Lamotrigine, also known by the brand name Lamictal, is a medication primarily used to treat epilepsy and bipolar disorder. It works by stabilizing electrical activity in the brain and is effective in reducing the frequency and severity of seizures and mood swings.

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The Prevalence and Management of Side Effects of Lithium and Anticonvulsants as Mood Stabilizers in Bipolar Disorder from a Clinical Perspective

research The Prevalence and Management of Side Effects of Lithium and Anticonvulsants as Mood Stabilizers in Bipolar Disorder from a Clinical Perspective

65 citations, July 2013 in “International Clinical Psychopharmacology”

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

research How Should You Use the Lab to Monitor Patients Taking a Mood Stabilizer

1 citations, July 2014 in “Current psychiatry”

Patients on mood stabilizers need regular health checks, but many aren't monitored properly.

research Hair Loss as a Side Effect of Lamotrigine Treatment

1 citations, July 2006 in “American Journal of Psychiatry”

Lamotrigine can cause hair loss.

research Lareb Provides Update on Lamotrigine-Associated Alopecia

July 2015 in “Reactions weekly”

Lamotrigine can cause hair loss in some patients.

research Summary of Findings on Psychotropic Medications

December 2006 in “The Brown University Psychopharmacology Update”

Second-generation antipsychotics offer no significant benefit over first-generation ones for schizophrenia.

research Dermatologic Side Effects of Psychotropic Medications

31 citations, October 2013 in “Psychosomatics”

Psychotropic medications can cause skin reactions, including severe conditions like SJS and TEN, and it's important for psychiatrists to recognize and manage these side effects.

research Dermatological Manifestations of Stress in Normal and Psychiatric Populations

22 citations, November 2014 in “Psychiatric Clinics of North America”

Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.

Long-Term Control of Epileptic Drop Attacks With the Combination of Valproate, Lamotrigine, and a Benzodiazepine: A Proof of Concept, Open Label Study

research Long-Term Control of Epileptic Drop Attacks With the Combination of Valproate, Lamotrigine, and a Benzodiazepine: A Proof of Concept, Open Label Study

21 citations, April 2011 in “Epilepsia”

The drug combination significantly reduced epileptic drop attacks in patients.

research Anticonvulsant-Induced Cutaneous Reactions

18 citations, January 1999 in “CNS Drugs”

Some anticonvulsant drugs can cause skin reactions, ranging from mild to severe, and managing these reactions is important for patient care.

research Postmarketing Surveillance of New Antiepileptic Drugs: The Tribulations of Trials

12 citations, September 2002 in “Epilepsia”

Monitoring new epilepsy drugs after they're sold is crucial to find rare and long-term side effects that initial tests might miss.

Bipolar Disorders and Valproate: Pharmacokinetics, Pharmacodynamics, Therapeutic Effects, and Indications of Valproate: Review of Articles

research Bipolar Disorders and Valproate: Pharmacokinetics, Pharmacodynamics, Therapeutic Effects, and Indications of Valproate: Review of Articles

11 citations, January 2016 in “Bipolar Disorder”

Valproate is a mood stabilizer for bipolar disorder but has side effects and risks, especially during pregnancy.

research Issues in the Treatment of Epilepsy

4 citations, August 2001 in “Epilepsia”

Treating epilepsy is complex, requiring careful drug choice and patient adherence to manage seizures and side effects.

research Alopecia in Association with Lamotrigine Use

13 citations, July 2010 in “Drug safety”

Lamotrigine may cause hair loss, affecting treatment compliance and health.