Hair Loss as a Side Effect of Lamotrigine Treatment

    July 2006 in “ American Journal of Psychiatry ”
    Thomas Hillemacher, Stefan Bleich, J. KORNHUBER, H. FRIELING
    TLDR Lamotrigine can cause hair loss.
    A 63-year-old woman with bipolar disorder experienced increased hair loss 2-3 weeks after starting lamotrigine treatment, which was confirmed by a trichogram showing increased telogen and dystrophic hair. The hair loss, primarily around the temporal bone, ceased after discontinuing lamotrigine, suggesting a causal link. This case was notable as it was the first to report a direct connection between lamotrigine and alopecia, highlighting the need for awareness of this rare side effect among patients and clinicians.
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