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    Glossary Tryptophan

    essential amino acid involved in serotonin and melatonin production

    Tryptophan, also known as L-Tryptophan, is an essential amino acid that the body cannot produce on its own and must obtain from dietary sources like turkey, eggs, and dairy. It plays a crucial role in the production of serotonin, a neurotransmitter that regulates mood, and melatonin, a hormone that controls sleep-wake cycles.

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    1. Skin l‐tryptophan‐2,3‐dioxygenase and rat hair growth FEBS Letters · 1993 · 33 citations
    2. Scleroderma and L-tryptophan: A possible explanation of the eosinophilia-myalgia syndrome Journal of The American Academy of Dermatology · 1990 · 21 citations
    3. Cutaneous Mucinosis in a Patient With Eosinophilia-Myalgia Syndrome Associated With L-Tryptophan Ingestion Archives of Dermatology · 1990 · 11 citations
    4. On the Role of Melatonin in Skin Physiology and Pathology Endocrine journal · 2005 · 222 citations
    5. Riboflavin-responsive glutaryl CoA dehydrogenase deficiency Molecular Genetics and Metabolism · 2005 · 25 citations
    6. Dermal Mucinosis in the Eosinophilia-Myalgia Syndrome Archives of Dermatology · 1990 · 8 citations
    7. Telogen effluvium associated with eosinophilia-myalgia syndrome Journal of The American Academy of Dermatology · 1991 · 5 citations
    8. The eosinophilia-myalgia syndrome Clinics in Dermatology · 1994 · 4 citations
    9. Indole-based derivatives effect on rats with polycystic ovary syndrome Journal of Pharmaceutical Investigation · 2017
    10. High-resolution structures of mutants of residues that affect access to the ligand-binding cavity of human lipocalin-type prostaglandin D synthase Acta Crystallographica Section D-biological Crystallography · 2014 · 5 citations
    11. Comparison of the Pathology of Fascia in Eosinophilic Myalgia Syndrome Patients and Idiopathic Eosinophilic Fasciitis Dermatology · 1993 · 11 citations
    12. A patient with eosinophilia-myalgia syndrome. PubMed · 1990 · 1 citations
    13. Design, Synthesis and Anxiolytic Activity Evaluation of N-Acyltryptophanyl- Containing Dipeptides, Potential TSPO Ligands# Medicinal Chemistry · 2018 · 16 citations
    14. Eosinophilic Fasciitis Associated With Tryptophan Ingestion Archives of dermatology · 1991 · 20 citations
    15. NIGELLA SATIVA L.: AN OVERVIEW Ankara Universitesi Eczacilik Fakultesi Dergisi · 2024
    16. Dietary supplementation with L-glutamine enhances immunity and reduces heat stress in Hanwoo steers under heat stress conditions 2022 · 3 citations
    17. HPLC-ESI-MSn characterization of phenolic compounds, terpenoid saponins, and other minor compounds in Bituminaria bituminosa Industrial Crops and Products · 2015 · 76 citations
    18. Adverse cutaneous reactions to chemotherapeutic agents and cytokine therapy Seminars in Cutaneous Medicine and Surgery · 1996 · 18 citations
    19. Different Ligands of the TRPV3 Cation Channel Cause Distinct Conformational Changes as Revealed by Intrinsic Tryptophan Fluorescence Quenching 2015 · 7 citations
    20. Influence of Amino Acids on the Hair Structure Before and During Chemical Treatments Universal library of medical and health sciences. · 2025
    21. Serotoninergic and melatoninergic systems are fully expressed in human skin ˜The œFASEB journal · 2002 · 249 citations
    22. Tryptophan in human hair: correlation with pigmentation ˜Il œFarmaco · 2000 · 16 citations
    23. Are Women with Polycystic Ovary Syndrome at Increased Risk of Alzheimer Disease? Lessons from Insulin Resistance, Tryptophan and Gonadotropin Disturbances and Their Link with Amyloid-Beta Aggregation Biomolecules · 2024 · 4 citations
    24. An Investigation of Hair and its Keratin Associated Proteins using Advanced Light Microscopy Durham e-Theses (Durham University) · 2019
    25. Pellagra and anorexia nervosa: a case report Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity · 2019 · 8 citations
    26. From Diospyros kaki L. (Persimmon) Phytochemical Profile and Health Impact to New Product Perspectives and Waste Valorization Nutrients · 2021 · 43 citations
    27. Periplaneta americana extract (L.) promotes hair regrowth in Alopecia areata mice by reducing inflammation and modulating skin microbiota Frontiers in Pharmacology · 2025
    28. Ajuga reptans L. Herb Extracts: Phytochemical Composition and Pharmacological Activity Screening Plants · 2025
    29. Pregnenolone for the treatment of L-DOPA-induced dyskinesia in Parkinson's disease Experimental neurology · 2023 · 2 citations
    30. Exploring the Efficacy and Potential Mechanisms of Topical Periplaneta americana (L.) Extract in Treating Androgenetic Alopecia in a Mouse Model: A Systems Pharmacology and Skin Microbiome Analysis Biology · 2025