Search
for

    Did you mean Keratin 17?
    Glossary Keratin 17

    protein crucial for skin, hair, and nail structure

    Keratin 17 (K17) is a type of protein found in the skin, hair follicles, and nails, playing a crucial role in their structural integrity and resilience. It is also involved in cellular processes like growth and repair, and its abnormal expression is linked to certain skin disorders and cancers.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. Clinicopathological features and expression of four keratins (K10, K14, K17 and K19) in six cases of eruptive vellus hair cysts Clinical and Experimental Dermatology · 2014 · 8 citations
    2. A Novel Mouse Type I Intermediate Filament Gene, Keratin 17n (K17n), Exhibits Preferred Expression in Nail Tissue Journal of Investigative Dermatology · 2004 · 31 citations
    3. Keratin expression in the normal nail unit: markers of regional differentiation British Journal of Dermatology · 2000 · 119 citations
    4. Keratin 17 null mice exhibit age- and strain-dependent alopecia Genes & Development · 2002 · 122 citations
    5. Keratinocyte differentiation in psoriatic scalp: morphology and expression of epithelial keratins British Journal of Dermatology · 2006 · 63 citations
    6. Is thyrotropin-releasing hormone a novel neuroendocrine modulator of keratin expression in human skin? British Journal of Dermatology · 2013 · 10 citations
    7. Onset of Keratin 17 Expression Coincides with the Definition of Major Epithelial Lineages during Skin Development The Journal of Cell Biology · 1998 · 318 citations
    8. Keratin 17 mutations cause either steatocystoma multiplex or pachyonychia congenita type 2 British Journal of Dermatology · 1998 · 175 citations
    9. Keratin 17 modulates hair follicle cycling in a TN<i>Fα</i>-dependent fashion Genes & Development · 2006 · 169 citations
    10. Keratin 17 Expression in the Hard Epithelial Context of the Hair and Nail, and its Relevance for the Pachyonychia Congenita Phenotype Journal of Investigative Dermatology · 2000 · 88 citations
    11. Keratin 17 in disease pathogenesis: from cancer to dermatoses Journal of pathology · 2018 · 62 citations
    12. Vibrissa hair bulge houses two populations of skin epithelial stem cells distinct by their keratin profile ˜The œFASEB journal · 2007 · 45 citations
    13. Biochemical and immunohistochemical analyses of keratin expression in basal cell carcinoma Journal of Dermatological Science · 1998 · 37 citations
    14. Type I Keratin 17 Protein Is Phosphorylated on Serine 44 by p90 Ribosomal Protein S6 Kinase 1 (RSK1) in a Growth- and Stress-dependent Fashion 2011 · 30 citations
    15. Development, Structure, and Keratin Expression in <i>C57BL/6J</i> Mouse Eccrine Glands Veterinary pathology · 2011 · 29 citations
    16. Psoriasis patients demonstrate HLA-Cw*06:02 allele dosage-dependent T cell proliferation when treated with hair follicle-derived keratin 17 protein Scientific Reports · 2018 · 27 citations
    17. <i>In vivo</i> alteration of the keratin 17 gene in hair follicles by oligonucleotide‐directed gene targeting Experimental Dermatology · 2003 · 8 citations
    18. Keratin 17 Impacts Global Gene Expression and Controls G2/M Cell Cycle Transition in Ionizing Radiation–Induced Skin Damage 2023 · 3 citations
    19. Signaling from keratins The Journal of Cell Biology · 2006
    20. The expanding significance of keratin intermediate filaments in normal and diseased epithelia Current opinion in cell biology · 2012 · 186 citations
    21. Differential Evolution of the Epidermal Keratin Cytoskeleton in Terrestrial and Aquatic Mammals Molecular Biology and Evolution · 2018 · 68 citations
    22. Exploiting the Keratin 17 Gene Promoter To Visualize Live Cells in Epithelial Appendages of Mice Molecular and Cellular Biology · 2005 · 58 citations
    23. The in vitro Assembly of Hair Follicle Keratins: Comparison of Cortex and Companion Layer Keratins Biological chemistry · 2002 · 13 citations
    24. Faculty Opinions recommendation of The keratins of the human beard hair medulla: the riddle in the middle. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2010
    25. In vivo Alteration of the Keratin 17 Gene in Hair Follicles by Oligonucleotide-directed Gene Targeting Chinese Journal of Dermatology · 2004
    26. Expression patterns of hair and epithelial keratins and transcription factors HOXC13, LEF1, and β‐catenin in a malignant pilomatricoma: a histological and immunohistochemical study Journal of Cutaneous Pathology · 2005 · 27 citations
    27. Expression of hair keratins in the adult nail unit: an immunohistochemical analysis of the onychogenesis in the proximal nail fold, matrix and nail bed British Journal of Dermatology · 2004 · 110 citations
    28. Pachyonychia congenita: Sporadic onset with mutation analysis Indian dermatology online journal · 2023
    29. Defining the complex epithelia that comprise the canine claw with molecular markers of differentiation Veterinary Dermatology · 2009 · 6 citations
    30. Milia may originate from the outermost layers of the hair bulge of the outer root sheath: A case report Oncology Letters · 2016