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    Glossary Interfollicular Stem Cells

    cells in skin between hair follicles aiding epidermis repair

    Interfollicular stem cells are a type of stem cell found in the skin, specifically in the areas between hair follicles. These cells play a crucial role in the regeneration and repair of the skin's outer layer, the epidermis, by continuously producing new skin cells to replace those that are shed or damaged.

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    1. Transient expression of keratin 19 is induced in originally negative interfollicular epidermal cells by adhesion of suspended cells. PubMed · 2005 · 25 citations
    2. Interfollicular epidermal stem-like cells for the recreation of the hair follicle epithelial compartment Stem cell research & therapy · 2021 · 14 citations
    3. Stem Cells in the Hair Follicle and Interfollicular Epidermis of Mice following Topical Application of Fluocinolone Acetonide Journal of Investigative Dermatology · 2007 · 2 citations
    4. 331 Characterisation of interfollicular stem cells and early TA cells during the transition from infant to child skin Journal of Investigative Dermatology · 2021
    5. Krt6a-Cre Transgenic Mice Direct LoxP-Mediated Recombination to the Companion Cell Layer of the Hair Follicle and Following Induction by Retinoic Acid to the Interfollicular Epidermis Journal of Investigative Dermatology · 2004 · 10 citations
    6. Analysis on the maintenance mechanisms of human interfollicular epidermal stem cell and their niche Journal of dermatological science · 2016
    7. Differential expression of stem cell markers in human follicular bulge and interfollicular epidermal compartments Histochemistry and Cell Biology · 2010 · 28 citations
    8. 1337 Single cell transcriptome profiling of human interfollicular epidermis reveals robust heterogeneity and divergent differentiation lineages Journal of Investigative Dermatology · 2018
    9. Hair follicle stem cells and intrafollicular homeostasis TURKDERM · 2014 · 1 citations
    10. Hair follicle and interfollicular epidermal stem cells make varying contributions to wound regeneration Cell Cycle · 2015 · 47 citations
    11. Hair follicle epithelial stem cells contribute to interfollicular epidermis during homeostasis JCI Insight · 2025 · 1 citations
    12. Human hair follicle and interfollicular keratinocyte reactivity to mouse HPV16-transformed cells: An in vitro study Oncology Reports · 2008 · 9 citations
    13. 1323 The effects of 3-OH of kaempferol on interfollicular epidermal stem cell fate Journal of Investigative Dermatology · 2018
    14. Toxicological Responses in Keratinocyte Interfollicular Stem Cells 2018
    15. WIF1 Is Expressed by Stem Cells of the Human Interfollicular Epidermis and Acts to Suppress Keratinocyte Proliferation Journal of Investigative Dermatology · 2013 · 18 citations
    16. The arrector pili muscle, the bridge between the follicular stem cell niche and the interfollicular epidermis Anatomical Science International · 2016 · 14 citations
    17. Outer root sheath (ORS) cells organize into epidermoid cyst-like spheroids when cultured inside Matrigel: a light-microscopic and immunohistological comparison between human ORS cells and interfollicular keratinocytes Cell and Tissue Research · 1994 · 36 citations
    18. Folliculotropic mycosis fungoides with central nervous system involvement: Demonstration of tumor clonality in intrafollicular T cells using laser capture microdissection Journal of the American Academy of Dermatology · 2003 · 14 citations
    19. The malignant capacity of skin tumours induced by expression of a mutant H-ras transgene depends on the cell type targeted Current Biology · 1998 · 153 citations
    20. Induction of ornithine decarboxylase in specific subpopulations of murine epidermal cells following multiple exposures to 12-<i>O</i>-tetradecanoylphorbol-13-acetate, mezerein and ethyl phenylpropriolate Carcinogenesis · 1992 · 26 citations
    21. Hair Follicle Reconstruction and Stem Cells InTech eBooks · 2017 · 2 citations
    22. Identification of the cell lineage at the origin of basal cell carcinoma Nature Cell Biology · 2010 · 351 citations
    23. Concise Review: Wnt Signaling Pathways in Skin Development and Epidermal Stem Cells Stem cells · 2017 · 105 citations
    24. 25 Years of Epidermal Stem Cell Research Journal of Investigative Dermatology · 2012 · 55 citations
    25. α3β1-integrin regulates hair follicle but not interfollicular morphogenesis in adult epidermis Journal of Cell Science · 2003 · 45 citations
    26. The importance and use of stem cells in dermatology Dermatology Review · 2016 · 6 citations
    27. Keratinocyte Stem Cells: Role in Aging IntechOpen eBooks · 2022 · 1 citations
    28. Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis Cell stem cell · 2009 · 503 citations
    29. Single-Cell Transcriptomics of Traced Epidermal and Hair Follicle Stem Cells Reveals Rapid Adaptations during Wound Healing Cell Reports · 2018 · 209 citations
    30. Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition Cell stem cell · 2016 · 174 citations