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    Glossary Integrins

    proteins on cell surfaces aiding attachment and communication

    Integrins are proteins found on the surface of cells that help them attach to and communicate with their surrounding environment, including other cells and the extracellular matrix. They play a crucial role in various biological processes such as cell signaling, immune responses, and wound healing, making them essential for maintaining tissue structure and function.

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    1. Integrin signalling regulates YAP/TAZ to control skin homeostasis Development · 2016 · 266 citations
    2. Targeting integrin pathways: mechanisms and advances in therapy Signal Transduction and Targeted Therapy · 2023 · 54 citations
    3. α3β1-integrin regulates hair follicle but not interfollicular morphogenesis in adult epidermis Journal of Cell Science · 2003 · 45 citations
    4. Targeted inactivation of integrin-linked kinase in hair follicle stem cells reveals an important modulatory role in skin repair after injury Molecular Biology of the Cell · 2011 · 22 citations
    5. β1 Integrins with Individually Disrupted Cytoplasmic NPxY Motifs Are Embryonic Lethal but Partially Active in the Epidermis Journal of Investigative Dermatology · 2013 · 17 citations
    6. Essential Role for Integrin-Linked Kinase in Melanoblast Colonization of the Skin Journal of Investigative Dermatology · 2019 · 14 citations
    7. Integrin β1 Establishes Liver Microstructure and Modulates Transforming Growth Factor β during Liver Development and Regeneration American Journal Of Pathology · 2020 · 10 citations
    8. Multiple Roles of Integrin-Linked Kinase in Epidermal Development, Maturation and Pigmentation Revealed by Molecular Profiling PLOS ONE · 2012 · 9 citations
    9. The Yin and Yang of Integrin Function in Re-Epithelialization During Wound Healing Advances in Wound Care · 2013 · 8 citations
    10. Promotion of mouse ameloblast proliferation by Lgr5 mediated integrin signaling Journal of Cellular Biochemistry · 2013 · 7 citations
    11. RGDSP-functionalized peptide hydrogel stimulates growth factor secretion via integrin αv/PI3K/AKT axis for improved wound healing by human amniotic mesenchymal stem cells Frontiers in Bioengineering and Biotechnology · 2024 · 6 citations
    12. Developmentally regulated expression of integrin alpha-6 distinguishes neural crest derivatives in the skin Frontiers in Cell and Developmental Biology · 2023 · 5 citations
    13. Blocking <i>α</i>1‐integrin reverts the adhesive phenotype of adult fibroblasts towards a foetal‐like migratory phenotype Experimental Dermatology · 2016 · 4 citations
    14. Knockout of integrin β1 in induced pluripotent stem cells accelerates skin-wound healing by promoting cell migration in extracellular matrix Stem Cell Research & Therapy · 2022 · 3 citations
    15. Loss of Dicer in Newborn Melanocytes Leads to Premature Hair Graying and Changes in Integrin Expression 2023 · 1 citations
    16. Angiopoietin-1 induces survival and proliferation of hair follicle dermal papilla cells through integrin α5β1 signaling Frontiers in Medicine · 2025
    17. Hair Follicular Expression of Integrin Alpha-6 Subunit and p63 in Hair Loss Journal of Clinical Dermatology · 2008
    18. The role of integrin alphavbeta6 in impaired wound healing and hair follicle regeneration 2010
    19. The focal adhesion protein PINCH-1 associates with EPLIN at integrin adhesion sites Journal of Cell Science · 2015 · 28 citations
    20. Hair-Growth-Promoting Effect of Conditioned Medium of High Integrin α6 and Low CD 71 (α6bri/CD71dim) Positive Keratinocyte Cells International Journal of Molecular Sciences · 2015 · 17 citations
    21. miR-3606-3p alleviates skin fibrosis by integratively suppressing the integrin/FAK, p-AKT/p-ERK, and TGF-β signaling cascades Journal of Advanced Research · 2024 · 15 citations
    22. Integrin α3β1 in hair bulge stem cells modulates CCN2 expression and promotes skin tumorigenesis Life science alliance · 2020 · 5 citations
    23. Data Sheet 1_Angiopoietin-1 induces survival and proliferation of hair follicle dermal papilla cells through integrin α5β1 signaling.pdf OPAL (Open@LaTrobe) (La Trobe University) · 2025
    24. 265 Loss of Langerhans cells in scar lesion of lichen planopilaris is caused by downregulation of integrin αvβ6 in the epidermal keratinocytes 2017
    25. Integrin-linked kinase inhibition via QLT0267 stops the epithelial outgrowth. OPAL (Open@LaTrobe) (La Trobe University) · 2015
    26. Keratin Biomaterials Activate Schwann Cells via Integrin‐Mediated Signaling and Promote Regeneration of Large Peripheral Nerve Defects in a Rabbit Model The FASEB Journal · 2009
    27. Integrando análise química e o saber popular: Tem cafeína no xampu bomba de café? Revista Iluminart · 2026
    28. The microanatomy of the distal arrector pili: possible role for α1β1 and α5β1 integrins in mediating cell‐cell adhesion and anchorage to the extracellular matrix Journal of Cutaneous Pathology · 2000 · 15 citations
    29. Beta 1 Integrin in Hair Follicles of Patients with Androgenetic Alopecia Benha Journal of Applied Sciences · 2024
    30. β1 Integrin Signaling Maintains Human Epithelial Progenitor Cell Survival In Situ and Controls Proliferation, Apoptosis and Migration of Their Progeny PLoS ONE · 2013 · 20 citations