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    GlossaryHair Follicle Integrity

    overall health and function of hair-producing skin structures

    Hair Follicle Integrity refers to the overall health and proper functioning of the hair follicle, which is the small organ in the skin that produces hair. Maintaining this integrity involves ensuring that the follicle's structure, blood supply, and cellular processes are all working correctly, which is crucial for healthy hair growth and preventing conditions like hair loss or alopecia.

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      learn GHK-Cu

      a copper peptide showing promise in both regrowth and reversing gray hair

      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn Tretinoin

      the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil

      learn Rosemary

      herb and oil with stimulant, circulatory, anti-inflammatory and antioxidant properties

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      community Verteporfin and Microneedling

      in Treatments 5 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.