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    Glossary Inhibitors

    substances that slow or prevent specific biological processes

    Inhibitors are substances that slow down or prevent specific chemical reactions or biological processes. In the context of hair and alopecia, inhibitors can target enzymes or pathways that contribute to hair loss, potentially offering therapeutic benefits by halting or reversing the condition.

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    Research 30 of 1000+

    1. Prevention of Chemotherapy-Induced Alopecia in Rats by CDK Inhibitors Science · 2001 · 153 citations
    2. Efficacy and safety of the oral Janus kinase inhibitor baricitinib in the treatment of adults with alopecia areata: Phase 2 results from a randomized controlled study Journal of The American Academy of Dermatology · 2021 · 66 citations
    3. LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1. Proceedings of the National Academy of Sciences of the United States of America · 1993 · 53 citations
    4. Inhibitors of 5α-Reductase in the Treatment of Benign Prostatic Hyperplasia Current pharmaceutical design · 2006 · 52 citations
    5. New 5?-reductase inhibitors: In vitro and in vivo effects Steroids · 2005 · 45 citations
    6. Evaluation of New Pregnane Derivatives as 5.ALPHA.-Reductase Inhibitor. Chemical & Pharmaceutical Bulletin · 2001 · 23 citations
    7. Inhibitors of 5α -Reductase Type I in LNCaP Cells from the Roots of Angelica koreana Planta Medica · 2002 · 22 citations
    8. Inhibidores de JAK: usos en dermatología. Parte 1: generalidades, aplicaciones en vitíligo y en alopecia areata Actas Dermo-Sifiliográficas · 2020 · 20 citations
    9. 5α-Reductase Inhibitors, Chemical and Clinical Models Steroids · 1998 · 17 citations
    10. Inhibitors of 5α-reductase-related side effects in patients seeking medical care for sexual dysfunction. PubMed · 2012 · 13 citations
    11. Synthesis and in Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides as 5.alpha.-Reductase Inhibitors and Antiandrogens Journal of Medicinal Chemistry · 1995 · 12 citations
    12. Activity of steroid 4 and derivatives 4a–4f as inhibitors of the enzyme 5α-reductase 1 Bioorganic & medicinal chemistry · 2018 · 3 citations
    13. Aromatase inhibitor–induced hair loss in two adolescents Pediatric Dermatology · 2020 · 1 citations
    14. Bioprospecting of Potential Inhibitors of 5alpha Reductase 2 Inhibitors from Relevant Ethno-pharmacological Plants via In Silico Techniques Scientific African · 2024
    15. In Search of Predictive Models for Inhibitors of 5-alpha Reductase 2 Based on the Integration of Bioactivity and Molecular Descriptors Data. IWBBIO · 2014
    16. Inhibitory effect of M50054, a novel inhibitor of apoptosis, on anti-Fas-antibody-induced hepatitis and chemotherapy-induced alopecia European Journal of Pharmacology · 2001 · 28 citations
    17. Pantothenic acid promotes dermal papilla cell proliferation in hair follicles of American minks via inhibitor of DNA Binding 3/Notch signaling pathway Life sciences · 2020 · 11 citations
    18. Inhibidor janus kinasa como opción terapéutica en alopecia areata. Reporte de caso 2021
    19. Proteasome Inhibitors: An Expanding Army Attacking a Unique Target Chemistry & biology · 2012 · 474 citations
    20. Intratumoral <i>De Novo</i> Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors Cancer research · 2011 · 402 citations
    21. JAK inhibitors in dermatology: The promise of a new drug class Journal of the American Academy of Dermatology · 2017 · 355 citations
    22. Emerging Topical and Systemic JAK Inhibitors in Dermatology Frontiers in Immunology · 2019 · 277 citations
    23. JAK-inhibitors. New players in the field of immune-mediated diseases, beyond rheumatoid arthritis Rheumatology · 2018 · 223 citations
    24. BRAF Inhibitor Dabrafenib in Patients with Metastatic <i>BRAF</i>-Mutant Thyroid Cancer Thyroid · 2014 · 188 citations
    25. Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib EBioMedicine · 2015 · 184 citations
    26. A phase 2a randomized, placebo-controlled study to evaluate the efficacy and safety of the oral Janus kinase inhibitors ritlecitinib and brepocitinib in alopecia areata: 24-week results Journal of the American Academy of Dermatology · 2021 · 138 citations
    27. Classification and management of skin, hair, nail and mucosal side-effects of epidermal growth factor receptor (EGFR) inhibitors European journal of cancer · 2007 · 138 citations
    28. JAK inhibitors for alopecia areata: a systematic review and meta‐analysis 2019 · 130 citations
    29. Epidermal differentiation: The role of proteases and their inhibitors European Journal of Cell Biology · 2004 · 118 citations
    30. Janus kinase inhibitors in dermatology: A systematic review Journal of the American Academy of Dermatology · 2017 · 116 citations