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    Did you mean Immune Activation?
    Glossary Immune Activation

    body's defense system responding to a perceived threat

    Immune activation refers to the process by which the body's immune system is triggered to respond to a perceived threat, such as an infection, injury, or foreign substance. This involves the activation of immune cells like T-cells and B-cells, which then work to identify, attack, and eliminate the threat. In the context of alopecia, immune activation can mistakenly target hair follicles, leading to hair loss.

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    Research 30 of 1000+

    1. Identifying key components and therapeutic targets of the immune system in hidradenitis suppurativa with an emphasis on neutrophils 2020 · 16 citations
    2. Transcriptional profiling in alopecia areata defines immune and cell cycle control related genes within disease-specific signatures Genomics · 2010 · 61 citations
    3. 1338 Epidermal growth factor receptor protects from immune privilege collapse and scarring hair follicle destruction 2023
    4. Environmental Modulation of JAK3-Mediated Immune Dysregulation in Alopecia Areata Scholarly Commons (Embry–Riddle Aeronautical University) · 2025
    5. Type 1 interferon signature and cytotoxic T lymphocyte activation targeted against sweat ducts in inflammatory acquired idiopathic generalized anhidrosis Journal of the European Academy of Dermatology and Venereology · 2023 · 6 citations
    6. 0037 Inflammatory implications in female pattern hair loss: unraveling B cell-related immune activation through comparative transcriptome profiling Journal of Investigative Dermatology · 2025
    7. Decision letter: Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of γδT-cells 2017
    8. 0034 Cross-species insights into hair follicle-T cell interactions in discoid lupus erythematosus: A comparison of human, canine and mouse models using spatial transcriptomics Journal of Investigative Dermatology · 2025
    9. Study the Effect of Inflammatory Cytokines on Hair Loss The Egyptian Journal of Medical Microbiology · 2025
    10. CAQ Corner: Basic concepts of transplant immunology Liver transplantation · 2022
    11. 0150 Single-cell and spatial transcriptome profiling reveals innate-adaptive crosstalk in alopecia areata Journal of Investigative Dermatology · 2025
    12. The Pathogenesis of Alopecia Areata in Rodent Models Journal of Investigative Dermatology Symposium Proceedings · 2003 · 23 citations
    13. CD27 and IL-35 as diagnostic biomarkers in alopecia areata: First evidence of association with pathogenic scalp bacterial infections Babcock University Medical Journal · 2025
    14. Topical metformin as a novel therapy for alopecia areata due to its immunologic effects Medical Hypotheses · 2023
    15. Aberrant B cell and cytotoxic T cell activation in female pattern hair loss: a pilot comparative clinico-transcriptomic study Journal of Investigative Dermatology · 2025
    16. Janus microneedles enabling orderly vitiligo treatment through spatiotemporal sequential promoting melanogenesis to transfer via PAR2 activation Asian Journal of Pharmaceutical Sciences · 2026
    17. Systemic humoral activation facilitates tissue regeneration by D-chiral biomaterial scaffolds Cell Biomaterials · 2026
    18. Peripheral MC1R Activation Modulates Immune Responses and is Neuroprotective in a Mouse Model of Parkinson’s Disease Journal of Neuroimmune Pharmacology · 2023 · 9 citations
    19. The Immun System Response İn Covıd-19 Infectıon İn Polycystıc Ovary Syndrome International Journal Of Medical Science And Clinical Invention · 2021 · 1 citations
    20. Tracing immune cells around biomaterials with spatial anchors during large-scale wound regeneration bioRxiv (Cold Spring Harbor Laboratory) · 2022 · 1 citations
    21. Immune-Mediated Diseases of the Central Nervous System Pediatric Clinics of North America · 2016 · 4 citations
    22. Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 1 citations
    23. Modification of the immune system with hydrogen sulfide and cyclosporine A International journal of medicine and psychology. · 2024
    24. Enhanced therapeutic effects of all-trans retinoic acid nanostructured lipid carrier composite gel drug delivery system for alopecia areata Journal of Nanobiotechnology · 2025
    25. What is behind the ‘swarm of bees’ in alopecia areata British Journal of Dermatology · 2018 · 7 citations
    26. Biomechanical Factors in Psoriatic Disease: Defective Repair Exertion as a Potential Cause. Hypothesis Presentation and Literature Review ACR Open Rheumatology · 2019 · 8 citations
    27. Plant Exosome Injections for Hair Follicle Proliferation and Immune Modulation: An Immunohistochemical Study Plastic & Reconstructive Surgery Global Open · 2026
    28. MẤT CÂN BẰNG GIỮA TẾ BÀO T ĐIỀU HÒA VÀ TẾ BÀO T GÂY ĐỘC TẾ BÀO TRONG RỤNG TÓC TỪNG MẢNG: KHI ĐẶC QUYỀN MIỄN DỊCH SỤP ĐỔ Tạp chí Da liễu học Việt Nam · 2026
    29. Signal transducer and activator of transcription 5B deficiency due to a novel missense mutation in the coiled-coil domain 2018 · 14 citations
    30. Down-RANKing the Threat of HSV-1: RANKL Upregulates MHC-Class-I-Restricted Anti-Viral Immunity in Herpes Simplex Virus Infection Journal of Investigative Dermatology · 2015 · 2 citations