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    Did you mean Immortalized Cell Line?
    Glossary Immortalized Cell Line

    cells modified to proliferate indefinitely in culture

    An immortalized cell line is a population of cells from a multicellular organism that has been modified to proliferate indefinitely in culture. This is achieved by introducing specific genes or by other means that prevent the normal cellular aging process, allowing researchers to study biological processes over extended periods without the cells dying.

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    Research 30 of 713

    1. Human Skin is a Steroidogenic Tissue: Steroidogenic Enzymes and Cofactors Are Expressed in Epidermis, Normal Sebocytes, and an Immortalized Sebocyte Cell Line (SEB-1) Journal of Investigative Dermatology · 2003 · 289 citations
    2. Multi-potentiality of a new immortalized epithelial stem cell line derived from human hair follicles In vitro cellular & developmental biology. Animal · 2008 · 34 citations
    3. Biosynthesis of Dihydrotestosterone by a Pathway that Does Not Require Testosterone as an Intermediate in the SZ95 Sebaceous Gland Cell Line Journal of Investigative Dermatology · 2009 · 36 citations
    4. Development and homeostasis of the sebaceous gland Seminars in Cell & Developmental Biology · 2012 · 107 citations
    5. Beyond acne: Current aspects of sebaceous gland biology and function Reviews in Endocrine and Metabolic Disorders · 2016 · 97 citations
    6. Androgens induce sebaceous differentiation in sebocyte cells expressing a stable functional androgen receptor 2015 · 31 citations
    7. Role of  -catenin in Epidermal Stem Cell Expansion, Lineage Selection, and Cancer Cold Spring Harbor Symposia on Quantitative Biology · 2008 · 61 citations
    8. 260 Establishment and characterization of human sebocytic progenitor cells that can differentiate into functional sebocytes Journal of Investigative Dermatology · 2017
    9. Sebaceous Gland Regeneration in Human Skin Xenografts Journal of Investigative Dermatology · 2010 · 9 citations
    10. Sebaceous immunobiology - skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations Frontiers in immunology · 2022 · 21 citations
    11. TGFβ signaling regulates lipogenesis in human sebaceous glands cells BMC Dermatology · 2013 · 44 citations
    12. Corticotropin-releasing hormone: An autocrine hormone that promotes lipogenesis in human sebocytes Proceedings of the National Academy of Sciences · 2002 · 284 citations
    13. The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells Journal of Investigative Dermatology · 2015 · 46 citations
    14. Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium Cell · 2019 · 181 citations
    15. Evidence of Heterogeneity and Quantitative Differences of the Type 1 5α-Reductase Expression in Cultured Human Skin Cells – Evidence of its Presence in Melanocytes Journal of Investigative Dermatology · 1998 · 83 citations
    16. Hair, Cutaneous Homeostasis and Stem Cell Functions Journal of Investigative Dermatology · 2014
    17. Inhibition of Insulin-Like Growth Factor-1–Induced Sebum Production by Bilobetin in Cultured Human Sebocytes Annals of Dermatology · 2019 · 8 citations
    18. Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin Aging Cell · 2009 · 62 citations
    19. Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways InTech eBooks · 2017 · 1 citations
    20. Hormonal therapy for acne: why not as first line therapy? facts and controversies Clinics in Dermatology · 2009 · 76 citations
    21. Indian Hedgehog Controls Proliferation and Differentiation in Skin Tumorigenesis and Protects against Malignant Progression Cell Reports · 2013 · 15 citations
    22. Gender-linked differences in human skin Journal of Dermatological Science · 2009 · 205 citations
    23. Marked Reduction of the Number and Individual Volume of Sebaceous Glands in Psoriatic Lesions Dermatology · 2016 · 10 citations
    24. Fatty acids and related lipid mediators in the regulation of cutaneous inflammation Biochemical Society Transactions · 2018 · 28 citations
    25. Aging Skin: A Window to the Body CRC Press eBooks · 2016 · 1 citations
    26. Biochemistry of epidermal stem cells Biochimica et Biophysica Acta (BBA) - General Subjects · 2012 · 26 citations
    27. Enhanced Differentiation Potential of Pigmented Human Epidermal Equivalents 2026
    28. Bad Hair Day: Testosterone and Wnts Journal of Investigative Dermatology · 2015 · 3 citations
    29. Review of Hair Follicle Dermal Papilla cells as <i>in vitro</i> screening model for hair growth International Journal of Cosmetic Science · 2018 · 76 citations
    30. TR3 is preferentially expressed by bulge epithelial stem cells in human hair follicles Laboratory Investigation · 2016 · 7 citations