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    Glossary Immortalized Cell Line

    cells modified to proliferate indefinitely in culture

    An immortalized cell line is a population of cells from a multicellular organism that has been modified to proliferate indefinitely in culture. This is achieved by introducing specific genes or by other means that prevent the normal cellular aging process, allowing researchers to study biological processes over extended periods without the cells dying.

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    Research 30 of 709

    1. Establishment of an immortalized mouse dermal papilla cell strain with optimized culture strategy PeerJ · 2018 · 3 citations
    2. Immortalized human hair follicle-derived mesenchymal-like stromal cells for the long-term production of scalable Immunomodulatory and regenerative secretome Stem Cell Research & Therapy · 2025 · 1 citations
    3. Protective Effect of Conditioned Medium of Immortalized Human Stem Cells from Exfoliated Deciduous Teeth Against Hair Graying Caused by X-Ray Irradiation via Its Antioxidative Activity Antioxidants · 2025
    4. Peer Review #2 of "Establishment of an immortalized mouse dermal papilla cell strain with optimized culture strategy (v0.1)" 2018
    5. Establishment and characterization of an immortalized human dermal papilla cell line BMB Reports · 2011 · 21 citations
    6. Establishment and Functional Characterization of Immortalized Rabbit Dermal Papilla Cell Lines Research Square (Research Square) · 2022
    7. Peer Review #2 of "Establishment of an immortalized mouse dermal papilla cell strain with optimized culture strategy (v0.2)" 2018
    8. Peer Review #1 of "Establishment of an immortalized mouse dermal papilla cell strain with optimized culture strategy (v0.1)" 2018
    9. Multi-potentiality of a new immortalized epithelial stem cell line derived from human hair follicles In vitro cellular & developmental biology. Animal · 2008 · 34 citations
    10. The establishment and characterization of immortalized human dermal papilla cells and their hair growth promoting effects Journal of Dermatological Science · 2010 · 13 citations
    11. Human Derived Immortalized Dermal Papilla Cells With a Constant Expression of Testosterone Receptor Frontiers in Cell and Developmental Biology · 2020 · 8 citations
    12. The Formation of Hair Follicle induced by Immortalized Human Dermal Papilla Cell Line in vivo The Chinese Journal of Dermatovenereology · 2011
    13. Human Skin is a Steroidogenic Tissue: Steroidogenic Enzymes and Cofactors Are Expressed in Epidermis, Normal Sebocytes, and an Immortalized Sebocyte Cell Line (SEB-1) Journal of Investigative Dermatology · 2003 · 289 citations
    14. Immortalized Rat Whisker Dermal Papilla Cells Cooperate with Mouse Immature Hair Follicle Buds to Activate Type IV Procollagenases in Collagen Matrix Coculture: Correlation with Ability to Promote Hair Follicle Development in Nude Mouse Grafts Journal of Investigative Dermatology · 1995 · 11 citations
    15. From Primary MSC Culture of Adipose Tissue to Immortalized Cell Line Producing Cytokines for Potential Use in Regenerative Medicine Therapy or Immunotherapy International Journal of Molecular Sciences · 2021 · 13 citations
    16. Establishment and characterization of matched immortalized human frontal and occipital scalp dermal papilla cell lines from androgenetic alopecia Scientific Reports · 2023
    17. Establishment and characterization of five immortalized human scalp dermal papilla cell lines Biochemical and Biophysical Research Communications · 2018 · 16 citations
    18. Establishment and Characterization of Immortalized Human Dermal Papilla Cells Expressing Human Papillomavirus 16 E6/E7 Journal of Microbiology and Biotechnology · 2023 · 1 citations
    19. Establishment and identification of immortalized sheep ovarian granulosa cells 2025
    20. Generation of an immortalized human hair follicle keratinocyte cell line retaining trichogenic potential Biochemical and Biophysical Research Communications · 2026
    21. Establishment and Functional Characterization of Immortalized Rabbit Dermal Papilla Cell Lines Research Square · 2021 · 2 citations
    22. Induction of meibocyte differentiation by three-dimensional, matrigel culture of immortalized human meibomian gland epithelial cells to form acinar organoids The Ocular Surface · 2022 · 19 citations
    23. Dermal papilla cells induce keratinocyte tubulogenesis in culture Elina S. ChermnykhEkaterina A. VorotelyakKsenia Y. Gnedeva • Marianna V. MoldaverYegor E. YegorovAndrey V. Vasiliev • 2010
    24. 583 RNA sequencing of immortalised balding and non balding DPCs identifies potential balding gene signatures Journal of Investigative Dermatology · 2022
    25. Induction of hair follicles using neonatal mouse dermis and human keratinocytes: relevance for improved burn wound treatments Open University of Cape Town (University of Cape Town) · 2020
    26. Mapping of a novel locus for keratosis follicularis squamosa on chromosome 7p14.3–7p12.1 Journal of Dermatological Science · 2010 · 4 citations
    27. Transfection of rat dermal papilla cells with a gene encoding a temperature-sensitive polyomavirus large T antigen generates cell lines retaining a differentiated phenotype Journal of Cell Science · 1994 · 25 citations
    28. Analysis of proliferation, apoptosis and keratin expression in cultured normal and immortalized human buccal keratinocytes European Journal Of Oral Sciences · 2003 · 27 citations
    29. Bioengineering of Hair Follicle-like Structure for Validation of Hair Growth Promoting Compounds Bioengineering · 2022
    30. Combinatorial expression of cell cycle regulators is more suitable for immortalization than oncogenic methods in dermal papilla cells iScience · 2021 · 5 citations