7 citations
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November 2020 in “Journal of The American Academy of Dermatology” This study found that low-dose oral minoxidil for androgenetic alopecia was associated with a higher incidence of hypertrichosis and edema compared to previous studies, but it remains a generally well-tolerated treatment option.
6 citations
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October 2011 in “Archives de pédiatrie” This case report describes a young girl who experienced vasoplegic shock and prolonged tachycardia after ingesting hair lotion containing minoxidil, highlighting the need for extended monitoring due to potential persistent hemodynamic issues.
4 citations
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September 2015 in “Case Reports” The authors describe a case of syncope in a young man after using high strength topical minoxidil, which resolved when he stopped the treatment, highlighting a rare documented reaction.
3 citations
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July 2018 in “Journal of Oral and Maxillofacial Surgery” This report describes two cases of postoperative alopecia following oral surgery, highlighting potential risk factors such as head positioning and prolonged operative time, and suggests prevention strategies.
2 citations
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June 2017 in “Pediatric Dermatology” This case report describes a 2-year-old boy in critical condition who developed anagen effluvium, possibly due to hypotension and hypoxia triggering hair follicle apoptosis.
August 2026 in “LUMEN ET VIRTUS” In this study, low-dose oral minoxidil for androgenetic alopecia was generally safe, showing small average changes in blood pressure and heart rate with infrequent cardiovascular issues, though monitoring is essential, especially in patients with conditions like hypertension or arrhythmias.
July 2026 in “British journal of surgery” This study found that a substantial number of patients continued tamsulosin and/or finasteride unnecessarily after prostate surgery, with poor documentation and communication contributing to this issue.
This study found that oral minoxidil is associated with a higher proportional reporting of several cardiovascular adverse events compared to topical minoxidil in spontaneous FDA reports, but these signals should be interpreted as hypothesis-generating rather than evidence of clinical safety.
August 2025 in “International Journal of Scientific Research” This study found that administering 5 mg of oral minoxidil daily for 24 weeks led to a 20.3% increase in hair density among men with androgenetic alopecia, although side effects like hypertrichosis and hypotension were observed.
This literature review suggests that oral minoxidil may improve tolerability compared to its topical form for treating androgenetic alopecia, although individual treatment plans are necessary due to differing side effects and response patterns.
October 2024 in “International Journal of Dermatology” In this meta-analysis, researchers found that oral and topical minoxidil treatments for androgenetic alopecia had similar efficacy in improving hair density and diameter, but oral minoxidil resulted in a higher incidence of hypertrichosis compared to topical use.
In this case report, a 23-year-old man experienced dizziness, blurred vision, malaise, and fatigue after excessive use of topical minoxidil for three days, with symptoms resolving once minoxidil was discontinued.
March 2024 in “Clinical, Cosmetic and Investigational Dermatology” Among Saudi dermatologists, this study reported widespread recognition of low-dose oral minoxidil's use for patterned hair loss and its side effect of hypertrichosis; however, many avoid prescribing it due to its unavailability in local pharmacies.
January 2024 in “Expert Opinion on Pharmacotherapy” This source suggests that oral minoxidil could be a safe and effective treatment option for both female and male androgenetic alopecia, although it is currently used off-label.
September 2023 in “Translational medicine reports” This case study reported that an 18-year-old woman ingested a large amount of topical minoxidil, leading to symptoms like low blood pressure, increased heart rate, and elevated liver enzymes, but recovered fully after treatment. Minoxidil toxicity may rarely cause abnormal liver enzyme levels.
October 2022 in “Journal of advanced research in medicine” This case study reports that a 52-year-old woman with Sheehan syndrome improved after receiving hormone replacement therapy, highlighting its importance for patients with similar symptoms.
July 2021 in “Research, Society and Development” This study reviewed literature on the adverse effects of Minoxidil in treating androgenetic alopecia, highlighting common reactions like hypertrichosis, scalp irritation, and contact dermatitis, while noting less frequent cardiovascular symptoms, concluding that the treatment is effective and generally well-tolerated.
May 2019 in “The Journal of Sexual Medicine” This study found that among premenopausal women taking flibanserin, consuming wine with an evening meal may increase the risk of syncope and orthostatic hypotension-related adverse events compared to placebo.
April 2017 in “The Journal of urology/The journal of urology” This study observed that both dutasteride and finasteride affected penile morphology in normotensive and hypertensive rats, with more pronounced changes in hypertensive animals, especially when treated with dutasteride.
June 2016 in “Makedonski medicinski pregled” This case report describes severe hypotension, acute coronary syndrome, tachycardia, and acute kidney failure in a man who ingested topical minoxidil, with eventual recovery following intensive treatment.
This article reviews the characteristics and risks associated with polycystic ovary syndrome, such as insulin resistance and obesity, highlighting a need for further understanding of its pathogenesis; it reports no new findings.
July 1999 in “Liver transplantation and surgery” Oxygen levels can drop during liver transplant if bypass pressures are too high, but other reasons should be checked first.
104 citations
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November 1978 in “JAMA” This article reviews the challenges of fasting and dietary regimens in producing sustained weight loss and reports no new research findings or results.
14 citations
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August 2020 in “Dermatologic Therapy” This study reported that low-dose oral minoxidil is generally safe for treating various types of hair loss, though it may cause hypertrichosis and pedal edema, especially at higher doses.
January 2023 in “Skin appendage disorders” This review discusses the potential of low-dose oral minoxidil as a safe and effective treatment for certain hair disorders, including alopecia, but reports no new clinical results.
August 2022 in “Journal of The American Academy of Dermatology” This study observed a slight reduction in blood pressure in normotensive patients after taking a 5-mg dose of oral minoxidil, particularly within the first two hours and more so in those with high baseline blood pressure.
37 citations
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May 2016 in “JAAD case reports” This abstract describes monilethrix, an autosomal dominant genodermatosis with symptoms like hair fragility and keratosis pilaris, and does not report new experimental results.
20 citations
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December 2015 in “Der Urologe” Combining medications is more effective for treating benign prostatic syndrome symptoms.
19 citations
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June 2020 in “International Journal of Dermatology” In this systematic review, oral minoxidil was found to be a safe and effective treatment for androgenetic alopecia and alopecia areata, with additional benefits for female pattern hair loss and other types of alopecia, although common side effects included hypertrichosis and postural hypotension.
15 citations
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April 2020 in “Journal of The American Academy of Dermatology” This article discusses the challenges of treating lichen planopilaris, reviews various therapeutic options including minoxidil, and reports no new clinical findings.