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This review discusses the design strategies and applications of long-acting polymeric microneedles, noting their potential to improve patient compliance and reduce side effects in chronic disease management, but reports no new experimental results.

In this animal study, the researchers found that biodegradable extracellular matrix scaffolds accelerated wound healing and enhanced hair follicle neogenesis in mice, suggesting a role for immune systems in tissue regeneration.

This study found that platelet-rich plasma microneedles promoted hair regrowth in mice by facilitating angiogenesis and cell proliferation, showing promise for a minimally invasive hair regeneration treatment.

This review examines the interaction between the extracellular matrix and immune cells in skin diseases and evaluates advanced therapies that target involved molecular mechanisms, reporting no new clinical findings.

In this review, the authors explored the diverse roles of fibroblasts in wound healing, suggesting that understanding their complexity could lead to better insights into wound pathologies and the development of new treatments.

This study found that strigolactone biosynthesis and signaling components in soybean may interact with other hormone pathways, influencing soybean development and nodulation.

This review discusses the unique advantages and challenges of microneedle arrays for vaccine and immunotherapy delivery but reports no new clinical results.

This study found that clindamycin-loaded PHA nanoparticles showed potent antibacterial effects against MRSA and enhanced wound healing in a mouse model of MRSA-infected wounds, indicating their potential as a novel treatment for these infections.

This study found that using insulin-like growth factor 1 with bone marrow-derived mesenchymal stem cells in a collagen-chitosan scaffold enhanced wound healing and hair follicle regeneration in rats.

This review highlights that the skin microbiota plays a crucial role in wound healing, with beneficial microorganisms aiding tissue repair and opportunistic pathogens hindering it, potentially guiding future microbiome-targeted therapies.

This review summarizes the roles of matricellular proteins in skin stem cell niches, highlighting their contribution to stem cell fate, self-renewal, and potential implications for wound healing and aging.

This review article addresses how the TRPV4 ion channel helps cells respond to mechanical and environmental stimuli, discussing its role in calcium signaling crucial for tissue repair and fibrosis across various organ systems, and highlighting potential therapeutic targets from animal and disease models.

This study investigated the molecular mechanisms of hair follicle morphogenesis in Ordos fine-wool sheep, identifying differential genes related to primary and secondary hair follicles, and providing important insights for improving wool quality and breeding strategies.

This review suggests that hyperspectral and terahertz imaging show promise in non-invasively assessing scalp changes associated with hair loss, but further validation is needed for clinical application.

In this study, chitosan hydrogels and delivery systems showed promise in supporting skin recovery post-laser procedures, enhancing topical treatments for acne and melasma, and improving hair density in scalp applications, but limited study sizes and formulation variability restrict generalizability.

This study found that late embryonic skin injuries can regenerate multiple tissue types, but this ability is hindered postnatally due to fibroblast-driven hyperinnervation, which can be mitigated to enable regeneration.

This review discusses advancements in skin microphysiological systems, such as 3D bioprinting, skin organoids, and skin-on-a-chip, and their effectiveness in emulating human skin functions for research and preclinical applications, highlighting the potential for replacing animal testing with these innovative technologies.

This study found that in female mice, softer, lightly crosslinked gelatin-based hydrogels promoted better wound healing with less scarring and inflammation compared to stiffer, heavily crosslinked hydrogels, affecting immune and stromal cell behavior.

This study found that although three-dimensional bioprinting in plastic and reconstructive surgery is rapidly advancing, complete tissue systems have not yet been successfully printed due to ongoing challenges.

This study found that hair mass index can effectively link hair productivity with clinical scalp coverage perception, suggesting its potential usefulness in diagnosing hair loss patterns and responses to treatment.

This paper discusses the potential roles of adipose tissue derived stem cells in skin regeneration and wound healing but emphasizes the need for further research on their effectiveness in clinical settings.

This article reviews the empirical use of algae in traditional remedies and highlights the need for scientific understanding of algae's bioactive compounds used in cosmetics without providing new experimental results.

In this review, researchers discussed recent advances in nanotechnology for topical skin applications, highlighting how nanocarriers enhance skin penetration and targeting in treatments for diseases like melanoma and psoriasis, while acknowledging that the penetration mechanisms and health impacts of nanoparticles remain not fully understood.

This review highlights the potential of marine macroalgae as a largely untapped resource for developing new active ingredients in the cosmetic industry, emphasizing their role in supporting circular economy models by utilizing waste from other industrial sectors.

This review discusses the experimental targets of fetal wound healing and evaluates existing therapies for scarless healing in adult skin, but reports no new research findings.

This abstract discusses the importance of developing intelligent and multifunctional dressings with skin-like properties for real-time wound monitoring, highlighting their potential to improve wound management, prognostic evaluation, and the integration of health monitoring into clinical practice.

This study found that fibronectin nanofiber dressings, made using rotary jet spinning, accelerated wound healing and improved tissue restoration in a full-thickness wound mouse model.

This review discusses transdermal drug delivery using hydrogel-forming microneedles and highlights their potential for disease treatment, but notes challenges in their clinical application.

In an animal model, this study found that PEG hydrogels delivering M2 macrophage-derived exosomes effectively promoted M1 to M2 macrophage transition and enhanced wound healing.

This review discusses the evolution and development of smart and multifunctional microneedles, highlighting their potential future importance in medical applications, but it reports no new experimental results.