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This review discusses the potential of topical nanoemulsions to transform skin cancer treatment by improving drug delivery and minimizing side effects, highlighting their advantages like enhanced skin permeation and controlled release, despite existing challenges.

In vitro skin models are improving but still need more innovation to fully replicate human skin.

This review highlights advancements in nanoemulgel platforms for topical and transdermal drug delivery, noting their improved safety and efficacy over conventional treatments in in vitro and in vivo studies, specifically for conditions like skin diseases and inflammatory issues.

This review covers the structure, development, cycle, and molecular regulation of hair follicles but does not report new results, aiming to offer insights for addressing hair follicle-related diseases.

This review explores recent advancements in understanding how various physiological and psychological factors, such as stress and aging, influence epidermal stem cell populations, highlighting their importance in immune-related skin disorders and potential for clinical applications.

Mechanical stretching can improve or hinder skin regeneration depending on duration.

This study found that injectable platelet-rich fibrin (i-PRF) showed improved hair growth in males with Type VI and Type VII alopecia, which are typically difficult to treat.

This study found that the film-trigger applicator system enhanced drug delivery efficiency and skin penetration of dissolving microneedles compared to traditional patch systems in both lab and animal models.

This review discusses the use of microbial biosurfactants as a safer alternative to chemical surfactants in cosmetics due to their antibacterial, moisturizing, and low toxicity properties, but it reports no new clinical findings.

This review explores the potential diagnostic and therapeutic applications of extracellular vesicles in treating various skin conditions but reports no new clinical study results.

This study demonstrates that using transwell culture significantly influences hair follicle formation in skin models, potentially improving dermatology and skin research methodologies.

This review discusses how functionalized hydrogels can modulate the microbiome to aid tissue regeneration and infection control, highlighting their potential to deliver therapeutic agents effectively and support beneficial immune responses.

This review examines advancements in lipid and inorganic nanocarriers, such as liposomes and inorganic nanoparticles, for transdermal drug delivery, noting enhanced absorption and stability but acknowledging that few have reached clinical use.

This review reports no new results but highlights the secretory function of keratinocytes, focusing on how various secretions, notably growth factors, impact stem cell differentiation into keratinocytes.

In this study, intradermal injection of GCSF-mobilized peripheral blood stem cells from young pigs rejuvenated skin in aged pigs by increasing collagen, elastin, and cell renewal rates.

This review highlights the potential of microneedles and nanomedicine in advancing tissue regeneration, emphasizing their innovative, localized, and minimally invasive approaches as promising solutions to current challenges in treating chronic wounds and degenerative diseases.

This study analyzed venture capital investments in plastic surgery from 2003 to 2023, finding $1.98 billion invested with a focus on general and facial cosmetic surgery, particularly minimally invasive devices, highlighting venture capital's significant role in shaping innovation in the sector.

This study in an animal model found that Rigenera® technology's use of autologous micrografts improved wound healing in diabetic rats by increasing factors like VEGF-A, IL4, and IL10 while reducing TNF-α and oxidative stress.

This review highlights the potential of natural hydrogels as advanced wound dressings, emphasizing their capabilities in mimicking the extracellular matrix, supporting healing, and delivering therapeutic agents for chronic and infected wound care.

This study showed that treating mouse fibroblasts with TTNPB can efficiently convert them into dermal-papilla-cell-like cells with strong hair-inducing capacity, suggesting potential for hair follicle regeneration therapies.

This review explores the advantages and limitations of using zebrafish models to study various skin diseases, but reports no new experimental results.

Inhibiting PGD2 and using dermal papilla cells may improve skin and hair regeneration.

This review explores the potential of cell-mediated drug delivery systems in dermatology, highlighting their ability to target inflamed or diseased skin while discussing applications in diseases like atopic dermatitis and melanoma, along with challenges such as immunogenicity and manufacturing.

This review examines how incorporating various polymers and active ingredients into polyurethane dressings can enhance their properties and adaptability for better wound repair and regeneration, suggesting a promising direction for developing advanced functional dressings.

This review reports that biopolymer-based hydrogels show promise as wound dressings due to their biocompatibility, moisture retention, and ability to mimic the extracellular matrix, though challenges in mass production, safety, and clinical validation remain.

This review highlights recent advances in personalized transdermal drug delivery systems, noting their potential for improved treatment efficacy and safety, but identifies significant challenges in clinical translation.

In this review, researchers examined advanced sensing technologies and bioelectronic interfaces that could improve understanding of the skin–brain axis, highlighting challenges and strategies for integrating these platforms into models for studying skin and neural interactions.

This study found that exosomes and secretome derived from rat hair follicle stem cells show promising potential for wound healing and tissue repair, demonstrating significant wound closure and suggesting their broader applicability in regenerative medicine.

In this review, the authors discuss caffeine's potential mechanisms and benefits as a hair loss treatment, noting its possible effectiveness and safety, though they caution that existing studies often have significant design flaws.

This review highlights the potential of exosomes as a novel therapeutic approach for skin diseases and aging, due to their stability, transportability, and ability to carry various bioactive compounds to target cells.