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    Glossary Hyperpigmentation

    condition where skin patches darken due to excess melanin

    Hyperpigmentation is a condition where patches of skin become darker than the surrounding areas due to an excess production of melanin, the pigment responsible for skin color. This can be caused by factors such as sun exposure, inflammation, hormonal changes, or certain medications, and is commonly seen in conditions like melasma, age spots, and post-inflammatory hyperpigmentation.

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    1. Postsclerotherapy Hyperpigmentation: A Histologic Evaluation The Journal of Dermatologic Surgery and Oncology · 1987 · 119 citations
    2. Reversible Hyperpigmentation of Skin and Nails With White Hair due to Vitamin B12 Deficiency Archives of Dermatology · 1986 · 77 citations
    3. Decrypting the Potential of Nanotechnology-Based Approaches as Cutting-Edge for Management of Hyperpigmentation Disorder Molecules · 2022 · 26 citations
    4. Nail, hair and skin hyperpigmentation associated with indinavir therapy AIDS · 2004 · 15 citations
    5. Reversible hyperpigmentation of skin and nails with white hair due to vitamin B12 deficiency Archives of Dermatology · 1986 · 11 citations
    6. Modified phenol peels for treatment‐refractory hyperpigmentation of lichen planus pigmentosus: A retrospective clinico‐dermoscopic analysis Journal of cosmetic dermatology · 2019 · 8 citations
    7. Genomic and transcriptomic landscape to decipher the genetic basis of hyperpigmentation in Lanping black-boned sheep (Ovis aries) BMC Genomics · 2024 · 7 citations
    8. A case of hyperpigmentation and acanthosis nigricans by testosterone injections Human & experimental toxicology · 2014 · 6 citations
    9. Hyperpigmentation, severe alopecia, and six days of instability in a case of severe methotrexate hypersensitivity reaction Daru · 2021 · 5 citations
    10. Localised Skin Hyperpigmentation as a Presenting Symptom of Vitamin B12 Deficiency Complicating Chronic Atrophic Gastritis Sultan Qaboos University medical journal · 2015 · 5 citations
    11. Hyperpigmentation following Treatment of Frontal Fibrosing Alopecia Case reports in dermatology · 2013 · 5 citations
    12. Bilaterally Symmetrical Alopecia With Reticulated Hyperpigmentation Veterinary Pathology · 2012 · 5 citations
    13. Fabrication of Thymoquinone and Ascorbic Acid-Loaded Spanlastics Gel for Hyperpigmentation: In Vitro Release, Cytotoxicity, and Skin Permeation Studies Pharmaceutics · 2025 · 4 citations
    14. Sodium Valproate-Induced Hyperpigmentation The Journal of Pediatrics · 2023 · 3 citations
    15. Fat grafts enriched with ex‐vivo expanded adipose stem cells improve hyperpigmentation of face Cell Biology International · 2023 · 3 citations
    16. Contact Dermatitis Associated with Alopecia and Hyperpigmentation Pediatric Dermatology · 2017 · 3 citations
    17. Erythromelanosis follicularis faciei et colli with reticulated hyperpigmentation of the extremities Clinical case reports · 2017 · 3 citations
    18. Hyperpigmentation Associated with the Use of Topical Cidofovir for Treatment of Trichodysplasia Spinulosa in an Immunosuppressed Adult: Case Report and Review of the Literature Skin · 2020 · 2 citations
    19. Design and development of cosmeceutical cream for hyperpigmentation and anti-aging International Journal of Advanced Community Medicine · 2018 · 2 citations
    20. Reversible Facial Hyperpigmentation Associated With Vitamin B12 Deficiency Nutrition in clinical practice · 2016 · 2 citations
    21. Spontaneous hair hyperpigmentation in response to vitamin intake in pregnancy—A clue for homocystinuria American Journal of Obstetrics and Gynecology · 1995 · 2 citations
    22. The Therapeutic and Preventive Effects of Light‐Emitting Diode (LED) for Post‐Inflammatory Erythema and Hyperpigmentation: A Pilot Study Photodermatology Photoimmunology & Photomedicine · 2025 · 1 citations
    23. Hyperpigmentation post laser hair removal in patients taking Vitamin D supplements Journal of Dermatology and Dermatologic Surgery · 2021 · 1 citations
    24. Skin Hyperpigmentation in Complex Regional Pain Syndrome (CRPS) (P3.315) Neurology · 2015 · 1 citations
    25. Evolution Of Anti-Hyperpigmentation Skincare: From Traditional Remedies To Modern Cosmeceutical Approaches For Adolescents Adolescencia e Saude · 2026
    26. Decoding Hyperpigmentation from Biological Mechanisms to Actives with Clinically Proven Topical Efficacy: A Narrative Review Dermatology and Therapy · 2026
    27. Nanostructured Lipid Carrier for Hyperpigmentation Treatment - a Dermal Prospective International Journal For Multidisciplinary Research · 2024
    28. Response Letter to “Contact Dermatitis Associated with Alopecia and Hyperpigmentation” Pediatric Dermatology · 2017
    29. Hypertrichosis and Hyperpigmentation in the Periocular Area Associated with Travoprost Treatment 2015
    30. Poikiloderma, hyperpigmentation, alopecia, hypohidrosis, malformed bones, lymphedema of the legs and decreased cortisol level: A new entity? Journal of dermatology · 2013