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Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Smoking harms skin health, causing slower wound healing, more wrinkles, and worsening some skin conditions, but may protect against certain others.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Cognitive behavioral strategies help women with PCOS make lifestyle changes to improve their health.

Patients with GATA2 deficiency show early skin symptoms that help diagnose the condition.

Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.

Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.

Women with lichen planopilaris often have thyroid disease, depression, anxiety, and may respond to treatment with slowed disease progression.

High mTORC1 activity slows hair growth and causes it to lose color.

New treatments for non-small cell lung cancer are being tested, with some already in use, focusing on immune response and targeting cancer cells, but side effects vary.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

Clinicians should understand tattoos to manage health issues, as tattoos can cause complications and affect medical assessments.

Skin problems are common after stem cell transplants, and early treatment by dermatologists can improve patient outcomes.

Disitamab vedotin and gemcitabine effectively treated bladder cancer without major side effects.

Ficus carica leaf extract may help treat melanoma by promoting cancer cell death without harming normal cells.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

Women with irregular periods should be checked for PCOS and treated early to prevent complications, with birth control pills helping to manage symptoms.

The document concludes that managing PCOS involves lifestyle changes, medication, and monitoring for associated health risks.

TREM2 macrophages and unsaturated lipids contribute to acne inflammation.

Cancer treatments can cause various eye problems, so eye doctors should know how to diagnose and treat these early.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

Activating NRF2 might help treat hair disorders by improving antioxidant defenses.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

GC10/DOX hydrogel shows promise as an effective thyroid cancer treatment.

A new method accurately detects bisphenols and parabens in human hair.