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Managing metabolic syndrome needs both lifestyle changes and medical treatments.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Herbal remedies can cause adverse effects and need more safety research.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

Testosterone therapy increases bone density in older men with low testosterone levels.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

DNA profiling in forensics has improved, but predicting physical traits and ancestry from DNA has limitations and requires ethical consideration.

Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

The document likely offers guidance on treating a woman's excessive hair growth, considering her symptoms and obesity.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

PGD2 stops hair growth and is higher in bald men with AGA.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.