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Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Finasteride effectively treats baldness but may cause sexual side effects.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Higher doses of cranial irradiation are linked to permanent hair loss.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

The paper concludes that the 1982 criteria for diagnosing systemic lupus erythematosus need updating to improve accuracy and involve dermatologists in the process.

Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.

Drug advertising has greatly increased, changing consumer behavior and raising concerns about its influence on healthcare and patient protection.

Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

The document concludes that proper diagnosis and a combination of medical, hair-care, and surgical treatments are important for managing alopecia in black women.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.

Men with hair loss experience lower quality of life, worsened by factors like age, severity, and treatment history.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.

Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.