research New Approaches to the Physiology of Histamine
Histamine plays key roles in immune responses, stomach acid, and brain signals.
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research Generalized Pruritus in Primary Sclerosing Cholangitis: Implications of Histamine Release by Lysophosphatidic Acid
A certain medication improved severe itching in a boy with liver and bowel disease by reducing histamine levels, suggesting a new treatment target.
research Influence of Glucocorticoids on Time-of-Day-Dependent Variation in Intradermal Reactivity to Histamine in Dogs
Glucocorticoids affect dogs' skin reactions to histamine, which vary by time of day.
research Application of Histamine Receptors H2R, H3R, and H4R, but Not H1R, in Dermatology
Certain histamine receptors (H2R, H3R, H4R) have unique roles in treating skin diseases, with H2R helping with chronic urticaria and other conditions, H3R providing pain relief and allergy benefits, and H4R reducing inflammation and itchiness.
research Effects of Botulinum Toxin Type A on Histamine-Induced Itch and Vasomotor Responses in Human Skin
Botulinum toxin type A reduces itch and inflammation from histamine and may help treat certain skin conditions and hair loss.
research Homeostatic Activation of Epidermal HSD11b1 Affects Skin Innervation and Non-Histaminergic Itch
HSD11b1 affects skin nerves and increases non-histaminergic itch.
research A Subpopulation of Itch-Sensing Neurons Marked by Ret and Somatostatin Expression
Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
research The Itchy Scalp: Scratching for an Explanation
Scalp itching is common and hard to diagnose due to the complex nerve structure of the scalp.
research Antianaphylactic Activity of Alcoholic Extract of Eclipta Alba
Alcoholic extract of Eclipta alba may help treat allergies and is safe at high doses.
research Mechanical Stimulation of Human Hair Follicle Outer Root Sheath Cultures Activates Adjacent Sensory Neurons
Touching hair can activate nearby nerve cells through signals from the hair's outer layer.
research Diffuse Hair Loss Following Multiple Honeybee Stings
A woman lost her hair from stress after a bee attack and her sister's death.
research Functional Medical Approach and Management for Long COVID
A functional medicine approach may help long COVID patients by focusing on adrenal fatigue, gut health, and vitamin D deficiency, using diagnostic tools and lifestyle changes.
research Effect of Nymphaea Caerulea Flower Extract on Improving Scalp Diseases
Nymphaea caerulea flower extract can improve scalp conditions by reducing oil, inflammation, stress hormones, and blood vessel issues.
research Circulation, Sensation, and Hair Growth: A Reply
The document suggests that nerve issues might contribute to hair loss and that testing sensation could predict these nerve problems.
research Adverse Effects of Opioid Analgesic Drugs
Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.
research Dermatologic Changes Associated With Interleukin 2 Administration
IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.
research Role of Nutritional Supplements in Selected Dermatological Disorders: A Review
Some diets and supplements might help with skin disorders, but their effectiveness varies and more research is needed.
research Urticaria, Drug Hypersensitivity Rashes, Nodules and Tumors, and Atrophic Diseases
The document concludes that various skin conditions have specific treatments, ranging from antihistamines for urticaria to surgery and medication for tumors and chronic skin diseases.
research Anhidrotic Effect of Intradermal Injections of Botulinum Toxin—A Comparison of Different Products and Concentrations
Different botulinum toxin products and concentrations can effectively reduce sweating, itching, bladder pressure, hair loss, and muscle spasms.
research Angioneurotic Edema Without C1 Esterase Inhibitor Abnormality: Efficacy of Tranexamic Acid
Tranexamic acid effectively reduced swelling episodes in a girl with a rare form of hereditary angioneurotic edema.
research TRPV3 as a Therapeutic Target for Itch
Blocking TRPV3 may help treat itch in dry skin conditions.
research SnapshotDx Quiz: February 2018
Blocking certain pathways with kinase inhibitors may help treat cutaneous lupus erythematosus.
research Hair Development and Langerhans Cell Migration During Human Embryogenesis
Langerhans cells and melanocytes migrate to the skin and hair follicles during early human development.
research Lack of a Gonadal or Adrenal Androgenic Mechanism for the Hypertrichosis Produced by Diazoxide, Phenytoin, and Minoxidil
These drugs cause hair growth without affecting testosterone or adrenal hormones.
research Efficacy and Safety of Omeprazole for Severe Gastroesophageal Reflux in Children
Omeprazole effectively treats severe acid reflux in children for short-term use, but long-term safety needs more research.
research Acute Hair Loss on the Limbs in Frontal Fibrosing Alopecia: A Clinicopathological Study of Two Cases
Frontal fibrosing alopecia can cause sudden hair loss on limbs, similar to scalp hair loss.
research Treatment of Hirsutism With Cimetidine: A Prospective Randomized Controlled Trial
Cimetidine did not reduce hair growth in women with hirsutism.
research Severe Steroid-Dependent Idiopathic Angioedema with Response to Rituximab
A woman with severe angioedema improved significantly after treatment with rituximab.
research Testosterone-Like Immunoreactivity in Hair Measured in Minute Sample Amounts: A Competitive Radioimmunoassay with an Adequate Limit of Detection
The new test can measure very small amounts of testosterone in hair, and grinding the hair up first gives more accurate results.
research Use of H-1 Antihistamine in Dermatology: More Than Itch and Urticaria Control: A Systematic Review
H-1 antihistamines may help with various skin conditions, but more research is needed to confirm their effectiveness.